131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment M D'Huyvetter, J De Vos, C Xavier, M Pruszynski, YGJ Sterckx, S Massa, ... Clinical cancer research 23 (21), 6616-6628, 2017 | 149 | 2017 |
New toxins homologous to ParE belonging to three‐component toxin–antitoxin systems in Escherichia coli O157:H7 R Hallez, D Geeraerts, Y Sterckx, N Mine, R Loris, L Van Melderen Molecular microbiology 76 (3), 719-732, 2010 | 135 | 2010 |
Immunogenicity risk profile of nanobodies C Ackaert, N Smiejkowska, C Xavier, YGJ Sterckx, S Denies, B Stijlemans, ... Frontiers in immunology 12, 632687, 2021 | 132 | 2021 |
Vibrio cholerae ParE2 poisons DNA gyrase via a mechanism distinct from other gyrase inhibitors J Yuan, Y Sterckx, LA Mitchenall, A Maxwell, R Loris, MK Waldor Journal of Biological Chemistry 285 (51), 40397-40408, 2010 | 85 | 2010 |
Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections JE Pinto Torres, J Goossens, J Ding, Z Li, S Lu, D Vertommen, P Naniima, ... Scientific reports 8 (1), 9019, 2018 | 71 | 2018 |
Small-angle X-ray scattering-and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2 YGJ Sterckx, AN Volkov, WF Vranken, J Kragelj, MR Jensen, L Buts, ... Structure 22 (6), 854-865, 2014 | 65 | 2014 |
Exploiting sequence and stability information for directing nanobody stability engineering P Kunz, T Flock, N Soler, M Zaiss, C Vincke, Y Sterckx, D Kastelic, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (9), 2196-2205, 2017 | 53 | 2017 |
Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF*♦ V Zorzini, A Mernik, J Lah, YGJ Sterckx, N De Jonge, A Garcia-Pino, ... Journal of Biological Chemistry 291 (21), 10950-10960, 2016 | 52 | 2016 |
Study of the Structural and Dynamic Effects in the FimH Adhesin upon α-d-Heptyl Mannose Binding S Vanwetswinkel, AN Volkov, YGJ Sterckx, A Garcia-Pino, L Buts, ... Journal of medicinal chemistry 57 (4), 1416-1427, 2014 | 50 | 2014 |
Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding V Zorzini, L Buts, E Schrank, YGJ Sterckx, M Respondek, ... Nucleic acids research 43 (2), 1241-1256, 2015 | 49 | 2015 |
Functionalization of gold nanoparticles with nanobodies through physical adsorption J Goossens, H Sein, S Lu, M Radwanska, S Muyldermans, YGJ Sterckx, ... Analytical Methods 9 (23), 3430-3440, 2017 | 45 | 2017 |
An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase S Odongo, YGJ Sterckx, B Stijlemans, D Pillay, T Baltz, S Muyldermans, ... PLoS neglected tropical diseases 10 (2), e0004420, 2016 | 42 | 2016 |
Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins L Qin, FB Bdira, YGJ Sterckx, AN Volkov, J Vreede, G Giachin, ... Nucleic Acids Research 3, 544-17, 2020 | 39 | 2020 |
A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2–ParE2 antitoxin–toxin complex YGJ Sterckx, T Jové, AV Shkumatov, A Garcia-Pino, L Geerts, ... Journal of Molecular Biology 428 (8), 1589-1603, 2016 | 38 | 2016 |
Novel half-life extended anti-MIF nanobodies protect against endotoxic shock A Sparkes, P De Baetselier, L Brys, I Cabrito, YGJ Sterckx, ... The FASEB Journal 32 (6), 3411, 2018 | 36 | 2018 |
Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon A Vandervelde, I Drobnak, S Hadži, YGJ Sterckx, T Welte, H De Greve, ... Nucleic acids research 45 (6), 2937-2950, 2017 | 33 | 2017 |
Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections Z Li, JE Pinto Torres, J Goossens, B Stijlemans, YGJ Sterckx, S Magez PLoS Neglected Tropical Diseases 14 (2), e0008044, 2020 | 22 | 2020 |
Structural basis for the specific neutralization of Stx2a with a camelid single domain antibody fragment RA Bernedo-Navarro, E Romão, T Yano, J Pinto, H De Greve, ... Toxins 10 (3), 108, 2018 | 20 | 2018 |
Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase J Pinto, S Odongo, F Lee, V Gaspariunaite, S Muyldermans, S Magez, ... PLoS neglected tropical diseases 11 (9), e0005932, 2017 | 20 | 2017 |
Identification of nanobodies against the acute myeloid leukemia marker CD33 E Romão, A Krasniqi, L Maes, C Vandenbrande, YGJ Sterckx, ... International journal of molecular sciences 21 (1), 310, 2020 | 19 | 2020 |