Subtype-dependent regulation of Gβγ signalling M Tennakoon, K Senarath, D Kankanamge, K Ratnayake, D Wijayaratna, ... Cellular signalling 82, 109947, 2021 | 42 | 2021 |
Dissociation of the G protein βγ from the Gq–PLCβ complex partially attenuates PIP2 hydrolysis D Kankanamge, S Ubeysinghe, M Tennakoon, PD Pantula, K Mitra, L Giri, ... Journal of Biological Chemistry 296, 2021 | 29 | 2021 |
The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics D Wijayaratna, K Ratnayake, S Ubeysinghe, D Kankanamge, ... Scientific Reports 13 (1), 2771, 2023 | 6 | 2023 |
Molecular regulation of PLCβ signaling S Ubeysinghe, D Wijayaratna, D Kankanamge, A Karunarathne Methods in Enzymology 682, 17-52, 2023 | 6 | 2023 |
Spatiotemporal optical control of Gαq-PLCβ interactions S Ubeysinghe, D Kankanamge, W Thotamune, D Wijayaratna, ... ACS Synthetic Biology 13 (1), 242-258, 2023 | 4 | 2023 |
Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling W Thotamune, S Ubeysinghe, KK Shrestha, ME Mostafa, MC Young, ... Journal of Biological Chemistry, 107481, 2024 | 1 | 2024 |
A new light on PLCβ! S Ubeysinghe, W Thotamune, A Karunarathne Cell Chemical Biology 31 (7), 1236-1238, 2024 | | 2024 |
Abstract 1248 A photosensitive Isoproterenol (OptoIso) delivers spatiotemporally precise cell surface and endomembrane-exclusive beta-adrenergic receptor signaling W Thotamune, S Ubeysinghe, K Shrestha, M Mostafa, J Edwards, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration W Thotamune, S Ubeysinghe, C Rajarathna, D Kankanamge, ... bioRxiv, 2024.06. 04.597473, 2024 | | 2024 |
Molecular regulation of GPCR-G-protein-governed PIP3 generation and its adaptation D Wijayaratna, K Ratnayake, S Ubeysinghe, D Kankanamge, ... bioRxiv, 2022.08. 31.506078, 2022 | | 2022 |
Optogenetic inhibition of subcellular GαqGTP signaling S Ubeysinghe, D Welivita, A Karunarathne The FASEB Journal 36, 2022 | | 2022 |