Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA T Sallam, M Jones, BJ Thomas, X Wu, T Gilliland, K Qian, A Eskin, ... Nature medicine 24 (3), 304-312, 2018 | 199 | 2018 |
IL-10 signaling remodels adipose chromatin architecture to limit thermogenesis and energy expenditure P Rajbhandari, BJ Thomas, AC Feng, C Hong, J Wang, L Vergnes, ... Cell 172 (1), 218-233. e17, 2018 | 159 | 2018 |
Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes P Rajbhandari, D Arneson, SK Hart, IS Ahn, G Diamante, LC Santos, ... Elife 8, e49501, 2019 | 139 | 2019 |
Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress Z Zhou, V Ribas, P Rajbhandari, BG Drew, TM Moore, AH Fluitt, ... Journal of Biological Chemistry 293 (13), 4735-4751, 2018 | 91 | 2018 |
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling Z Zhou, TM Moore, BG Drew, V Ribas, J Wanagat, M Civelek, M Segawa, ... Science translational medicine 12 (555), eaax8096, 2020 | 87 | 2020 |
Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation P Rajbhandari, KA Schalper, NM Solodin, SJ Ellison-Zelski, K Ping Lu, ... Oncogene 33 (11), 1438-1447, 2014 | 83 | 2014 |
Regulation of estrogen receptor α N-terminus conformation and function by peptidyl prolyl isomerase Pin1 P Rajbhandari, G Finn, NM Solodin, KK Singarapu, SC Sahu, JL Markley, ... Molecular and cellular biology, 2012 | 80 | 2012 |
A strategy for discovery of endocrine interactions with application to whole-body metabolism MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ... Cell metabolism 27 (5), 1138-1155. e6, 2018 | 71 | 2018 |
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP L Zhang, P Rajbhandari, C Priest, J Sandhu, X Wu, R Temel, A Castrillo, ... Elife 6, e28766, 2017 | 57 | 2017 |
Prdm4 induction by the small molecule butein promotes white adipose tissue browning NJ Song, S Choi, P Rajbhandari, SH Chang, S Kim, L Vergnes, SM Kwon, ... Nature chemical biology 12 (7), 479-481, 2016 | 54 | 2016 |
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs J Wang, P Rajbhandari, A Damianov, A Han, T Sallam, H Waki, ... The Journal of clinical investigation 127 (3), 987-1004, 2017 | 37 | 2017 |
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism S Pearson, A Loft, P Rajbhandari, J Simcox, S Lee, P Tontonoz, ... Genes & development 33 (13-14), 747-762, 2019 | 33 | 2019 |
Inhibition of PU. 1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis Q Liu, J Yu, L Wang, Y Tang, Q Zhou, S Ji, Y Wang, L Santos, ... Journal of Hepatology 73 (2), 361-370, 2020 | 29 | 2020 |
Peptidylprolyl isomerase Pin1 directly enhances the DNA binding functions of estrogen receptor α P Rajbhandari, MS Ozers, NM Solodin, CL Warren, ET Alarid Journal of Biological Chemistry 290 (22), 13749-13762, 2015 | 22 | 2015 |
Noggin depletion in adipocytes promotes obesity in mice AM Blázquez-Medela, M Jumabay, P Rajbhandari, T Sallam, Y Guo, ... Molecular metabolism 25, 50-63, 2019 | 21 | 2019 |
The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene GL Powers, P Rajbhandari, NM Solodin, B Bickford, ET Alarid PloS one 8 (12), e81110, 2013 | 16 | 2013 |
Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles RB Kang, Y Li, C Rosselot, T Zhang, M Siddiq, P Rajbhandari, AF Stewart, ... Genome Medicine 15 (1), 30, 2023 | 15 | 2023 |
IDOL regulates systemic energy balance through control of neuronal VLDLR expression SD Lee, C Priest, M Bjursell, J Gao, DV Arneson, IS Ahn, G Diamante, ... Nature metabolism 1 (11), 1089-1100, 2019 | 14 | 2019 |
A kinetic model identifies phosphorylated estrogen receptor-α (ERα) as a critical regulator of ERα dynamics in breast cancer D Tian, NM Solodin, P Rajbhandari, K Bjorklund, ET Alarid, PK Kreeger The FASEB Journal 29 (5), 2022, 2015 | 14 | 2015 |
Mammary duct luminal epithelium controls adipocyte thermogenic programme S Patel, NZR Sparman, D Arneson, A Alvarsson, LC Santos, SJ Duesman, ... Nature 620 (7972), 192-199, 2023 | 8 | 2023 |