Probes & drugs portal: an interactive, open data resource for chemical biology C Skuta, M Popr, T Muller, J Jindrich, M Kahle, D Sedlak, D Svozil, ... Nature methods 14 (8), 759-760, 2017 | 65 | 2017 |
Two panels of steroid receptor luciferase reporter cell lines for compound profiling D Sedlák, A Paguio, P Bartunek Combinatorial chemistry & high throughput screening 14 (4), 248-266, 2011 | 55 | 2011 |
Silychristin: Skeletal alterations and biological activities D Biedermann, M Buchta, V Holečková, D Sedlák, K Valentová, ... Journal of natural products 79 (12), 3086-3092, 2016 | 45 | 2016 |
Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors M Jurášek, P Džubák, D Sedlák, H Dvořáková, M Hajdúch, P Bartůněk, ... Steroids 78 (3), 356-361, 2013 | 42 | 2013 |
Synthesis and biochemical characterization of a series of 17α-perfluoroalkylated estradiols as selective ligands for estrogen receptor α B Eignerová, D Sedlák, M Dračínský, P Bartunek, M Kotora Journal of medicinal chemistry 53 (19), 6947-6953, 2010 | 38 | 2010 |
Lipophosphonoxins II: design, synthesis, and properties of novel broad spectrum antibacterial agents G Seydlová, R Pohl, E Zborníková, M Ehn, O Šimák, N Panova, ... Journal of Medicinal Chemistry 60 (14), 6098-6118, 2017 | 33 | 2017 |
c-Myb inhibits myogenic differentiation through repression of MyoD P Kaspar, P Pajer, D Sedlak, T Tamaoki, M Dvorak Experimental cell research 309 (2), 419-428, 2005 | 33 | 2005 |
Structure activity relationship studies on cytotoxicity and the effects on steroid receptors of AB-functionalized cholestanes L Rarova, J Steigerova, M Kvasnica, P Bartůněk, K Křížová, ... The Journal of Steroid Biochemistry and Molecular Biology 159, 154-169, 2016 | 30 | 2016 |
Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells L Rárová, S Zahler, J Liebl, V Kryštof, D Sedlák, P Bartůněk, L Kohout, ... Steroids 77 (13), 1502-1509, 2012 | 30 | 2012 |
PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome A Pelet, V Skopova, U Steuerwald, V Baresova, M Zarhrate, JM Plaza, ... Human Molecular Genetics 28 (22), 3805-3814, 2019 | 28 | 2019 |
Synthesis of ferrocenestrone: the first metallocene based steroid analogue F Hessler, I Císařová, D Sedlák, P Bartůněk, M Kotora Chemistry-a European Journal 18 (18), 5515, 2012 | 24 | 2012 |
Estradiol dimer inhibits tubulin polymerization and microtubule dynamics M Jurášek, M Černohorská, J Řehulka, V Spiwok, T Sulimenko, ... The Journal of Steroid Biochemistry and Molecular Biology 183, 68-79, 2018 | 23 | 2018 |
Structure–Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists D Sedlák, TA Wilson, W Tjarks, HS Radomska, H Wang, JN Kolla, ... Journal of Medicinal Chemistry 64 (13), 9330-9353, 2021 | 22 | 2021 |
Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity M Jurášek, P Džubák, S Rimpelová, D Sedlák, P Konečný, I Frydrych, ... Steroids 117, 97-104, 2017 | 22 | 2017 |
Synthesis and Evaluation of 17α-Arylestradiols as Ligands for Estrogen Receptor α and β D Sedlák, P Novák, M Kotora, P Bartunek Journal of medicinal chemistry 53 (10), 4290-4294, 2010 | 18 | 2010 |
Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells D Rysanek, P Vasicova, JN Kolla, D Sedlak, L Andera, J Bartek, Z Hodny Aging (Albany NY) 14 (16), 6381, 2022 | 16 | 2022 |
Development of a high-throughput fluorescence polarization assay to identify novel ligands of glutamate carboxypeptidase II G Alquicer, D Sedlák, Y Byun, J Pavlíček, M Stathis, C Rojas, B Slusher, ... Journal of biomolecular screening 17 (8), 1030-1040, 2012 | 16 | 2012 |
The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro L Rárová, D Sedlák, J Oklestkova, J Steigerová, J Liebl, S Zahler, ... The Journal of Steroid Biochemistry and Molecular Biology 178, 263-271, 2018 | 14 | 2018 |
Fluorescence-based high-throughput screening of dicer cleavage activity K Podolska, D Sedlak, P Bartunek, P Svoboda Journal of biomolecular screening 19 (3), 417-426, 2014 | 13 | 2014 |
Oxime-based 19-nortestosterone–pheophorbide a conjugate: Bimodal controlled release concept for PDT V Pavlíčková, M Jurášek, S Rimpelová, K Záruba, D Sedlák, M Šimková, ... Journal of materials chemistry B 7 (36), 5465-5477, 2019 | 11 | 2019 |