Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)) J Sileikytė, E Blachly-Dyson, R Sewell, A Carpi, R Menabò, F Di Lisa, ... Journal of Biological Chemistry 289 (20), 13769-13781, 2014 | 215 | 2014 |
Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition M Carraro, V Giorgio, J Šileikytė, G Sartori, M Forte, G Lippe, M Zoratti, ... Biochimica et Biophysica Acta (BBA) - Bioenergetics 1837 (supplement), e12, 2014 | 183 | 2014 |
Regulation of the inner membrane mitochondrial permeability transition by the outer membrane translocator protein (peripheral benzodiazepine receptor) J Šileikytė, V Petronilli, A Zulian, F Dabbeni-Sala, G Tognon, P Nikolov, ... Journal of Biological Chemistry 286 (2), 1046-1053, 2011 | 134 | 2011 |
Shedding light on the mitochondrial permeability transition F Ricchelli, J Šileikytė, P Bernardi Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (5), 482-490, 2011 | 110 | 2011 |
The mitochondrial permeability transition in mitochondrial disorders J Šileikytė, M Forte Oxidative medicine and cellular longevity 2019 (1), 3403075, 2019 | 81 | 2019 |
Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase A Carrer, L Tommasin, J Šileikytė, F Ciscato, R Filadi, A Urbani, M Forte, ... Nature communications 12 (1), 4835, 2021 | 65 | 2021 |
Discovery, synthesis, and optimization of diarylisoxazole‐3‐carboxamides as potent inhibitors of the mitochondrial permeability transition pore S Roy, J Šileikytė, M Schiavone, B Neuenswander, F Argenton, J Aubé, ... ChemMedChem 10 (10), 1655-1671, 2015 | 49 | 2015 |
Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress.: Unmasking pore-regulating external thiols V Petronilli, J Šileikytė, A Zulian, F Dabbeni-Sala, G Jori, S Gobbo, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (7), 897-904, 2009 | 46 | 2009 |
N‐Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore S Roy, J Šileikytė, B Neuenswander, MP Hedrick, TDY Chung, J Aubé, ... ChemMedChem 11 (3), 283-288, 2016 | 42 | 2016 |
Shutting down the pore: The search for small molecule inhibitors of the mitochondrial permeability transition J Šileikytė, M Forte Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (8), 1197-1202, 2016 | 39 | 2016 |
A novel class of cardioprotective small-molecule PTP inhibitors S Antonucci, M Di Sante, J Sileikyte, J Deveraux, T Bauer, MJ Bround, ... Pharmacological research 151, 104548, 2020 | 26 | 2020 |
Second‐generation inhibitors of the mitochondrial permeability transition pore with improved plasma stability J Šileikytė, J Devereaux, J de Jong, M Schiavone, K Jones, A Nilsen, ... ChemMedChem 14 (20), 1771-1782, 2019 | 23 | 2019 |
Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin A Stocco, N Smolina, P Sabatelli, J Šileikytė, E Artusi, V Mouly, M Cohen, ... Pharmacological Research 165, 105421, 2021 | 22 | 2021 |
Chemical proteomics approach for profiling the NAD interactome J Šileikytė, S Sundalam, LL David, MS Cohen Journal of the American Chemical Society 143 (18), 6787-6791, 2021 | 21 | 2021 |
The translocator protein (peripheral benzodiazepine receptor) mediates rat-selective activation of the mitochondrial permeability transition by norbormide A Zulian, J Šileikytė, V Petronilli, S Bova, F Dabbeni-Sala, G Cargnelli, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (12), 1600-1605, 2011 | 18 | 2011 |
Small Molecules Targeting the Mitochondrial Permeability Transition J Sileikyte, S Roy, P Porubsky, B Neuenswander, J Wang, M Hedrick, ... Probe Reports from the NIH Molecular Libraries Program, 2014 | 14 | 2014 |
Small molecules targeting the mitochondrial permeability transition, In Probe Reports from the NIH Molecular Libraries Program J Sileikyte, S Roy, P Porubsky, B Neuenswander, J Wang, M Hedrick, ... National Center for Biotechnology Information,(US), Place Published, 2010 | 6 | 2010 |
Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors MR Arnold, MF Langelier, J Gartrell, IT Kirby, DJ Sanderson, DS Bejan, ... Cell Chemical Biology 29 (12), 1694-1708. e10, 2022 | 4 | 2022 |
Second generation inhibitors of mitochondrial permeability transition pore with improved plasma stability M Cohen, M Forte, J Sileikyte, A Nilsen, J Devereaux, P Bernardi US Patent App. 17/636,327, 2022 | 1 | 2022 |
Shedding light on the permeability transition through S. cerevisiae F-ATP synthase mutagenesis M Carraro, L Guo, V Giorgio, V Checchetto, J Šileikytė, G Sartori, M Forte, ... 2016 EBEC Abstracts 1857, e62-e62, 2016 | 1 | 2016 |