Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer TT Wei, YT Lin, SP Tang, CK Luo, CT Tsai, CT Shun, CC Chen Oncogene 39 (2), 414-427, 2020 | 59 | 2020 |
Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development CT Tsai, CWE So Oncogene 36 (13), 1753-1759, 2017 | 56 | 2017 |
Transcriptional memory of cells of origin overrides β‐catenin requirement of MLL cancer stem cells T Siriboonpiputtana, BB Zeisig, M Zarowiecki, TK Fung, M Mallardo, ... The EMBO journal 36 (21), 3139-3155, 2017 | 29 | 2017 |
AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine CT Tsai, PM Yang, TR Chern, SH Chuang, JH Lin, L Klemm, M Müschen, ... Oncotarget 5 (1), 211, 2013 | 25 | 2013 |
Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia BB Zeisig, TK Fung, M Zarowiecki, CT Tsai, H Luo, B Stanojevic, C Lynn, ... Science Translational Medicine 13 (582), eabc4822, 2021 | 19 | 2021 |
Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia BH Yip, CT Tsai, JK Rane, W Vetharoy, E Anguita, S Dong, MA Caligiuri, ... haematologica 102 (8), e300, 2017 | 4 | 2017 |
Human platelet lysate enhances in vivo activity of CAR-Vδ2 T cells by reducing cellular senescence and apoptosis F Mo, CT Tsai, R Zheng, C Cheng, HE Heslop, MK Brenner, M Mamonkin, ... Cytotherapy, 2024 | 1 | 2024 |
313 Enhancing anti-cancer activity of therapeutic T-cells with a synapse-stabilizing receptor CT Tsai, N Watanabe, M Mamonkin Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Improved Anti-Tumor Potency of CAR Gamma Delta T Cells Expanded with Human Platelet Lysate F Mo, CT Tsai, M Mamonkin, N Watanabe MOLECULAR THERAPY 30 (4), 584-585, 2022 | | 2022 |
Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34-/Lo MLL-Rearranged Leukemia TK Fung, B Zeisig, M Zarowiecki, H Luo, CT Tsai, B Stanojevic, C Lynn, ... Blood 134, 3203, 2019 | | 2019 |
Loss of Asxl1 and Ezh2 cooperates in pathogenesis of haematological malignancies CT Tsai King’s College London, 2019 | | 2019 |