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Colin Hughes
Colin Hughes
Professor of Microbiology University of Cambridge, Fellow Trinity College Cambridge
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
V Koronakis, A Sharff, E Koronakis, B Luisi, C Hughes
Nature 405 (6789), 914-919, 2000
14132000
Structure and function of TolC: the bacterial exit duct for proteins and drugs
V Koronakis, J Eswaran, C Hughes
Annual review of biochemistry 73 (1), 467-489, 2004
4462004
Substrate‐induced assembly of a contiguous channel for protein export from E. coli: reversible bridging of an inner‐membrane translocase to an outer membrane exit pore
T Thanabalu, E Koronakis, C Hughes, V Koronakis
The EMBO journal, 1998
4321998
Swarming motility
GM Fraser, C Hughes
Current opinion in microbiology 2 (6), 630-635, 1999
4281999
Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation
JP Issartel, V Koronakis, C Hughes
Nature 351 (6329), 759-761, 1991
4001991
The assembled structure of a complete tripartite bacterial multidrug efflux pump
MF Symmons, E Bokma, E Koronakis, C Hughes, V Koronakis
Proceedings of the National Academy of Sciences 106 (17), 7173-7178, 2009
3592009
Structure of the periplasmic component of a bacterial drug efflux pump
MK Higgins, E Bokma, E Koronakis, C Hughes, V Koronakis
Proceedings of the National Academy of Sciences 101 (27), 9994-9999, 2004
3302004
Interactions underlying assembly of the Escherichia coli AcrAB–TolC multidrug efflux system
T Touzé, J Eswaran, E Bokma, E Koronakis, C Hughes, V Koronakis
Molecular microbiology 53 (2), 697-706, 2004
2872004
Isolation and analysis of the C‐terminal signal directing export of Escherichia coli hemolysin protein across both bacterial membranes.
V Koronakis, E Koronakis, C Hughes
The EMBO journal 8 (2), 595-605, 1989
2811989
RfaH and the ops element, components of a novel system controlling bacterial transcription elongation
MJA Bailey, C Hughes, V Koronakis
Molecular microbiology 26 (5), 845-851, 1997
2691997
Acylation of Escherichia coli Hemolysin: A Unique Protein Lipidation Mechanism Underlying Toxin Function
P Stanley, V Koronakis, C Hughes
Microbiology and molecular biology reviews 62 (2), 309-333, 1998
2651998
Co‐ordinate expression of virulence genes during swarm‐cell differentiation and population migration of Proteus mirabilis
C Ariison, HC Lai, C Hughes
Molecular microbiology 6 (12), 1583-1591, 1992
2621992
The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morganii are genetically related to each other and to the alpha-hemolysin of Escherichia coli
V Koronakis, M Cross, B Senior, E Koronakis, C Hughes
Journal of bacteriology 169 (4), 1509-1515, 1987
2601987
Fatty acylation of two internal lysine residues required for the toxic activity of Escherichia coli hemolysin
P Stanley, LC Packman, V Koronakis, C Hughes
Science 266 (5193), 1992-1996, 1994
2591994
Ability of Proteus mirabilis to invade human urothelial cells is coupled to motility and swarming differentiation
C Allison, N Coleman, PL Jones, C Hughes
Infection and Immunity 60 (11), 4740-4746, 1992
2391992
Cloning of the chromosomal determinants encoding hemolysin production and mannose-resistant hemagglutination in Escherichia coli
H Berger, J Hacker, A Juarez, C Hughes, W Goebel
Journal of bacteriology 152 (3), 1241-1247, 1982
2171982
Transition to the open state of the TolC periplasmic tunnel entrance
C Andersen, E Koronakis, E Bokma, J Eswaran, D Humphreys, C Hughes, ...
Proceedings of the National Academy of Sciences 99 (17), 11103-11108, 2002
2102002
Substrate‐specific binding of hook‐associated proteins by FlgN and FliT, putative chaperones for flagellum assembly
GM Fraser, JCQ Bennett, C Hughes
Molecular microbiology 32 (3), 569-580, 1999
2101999
Bacterial swarming: an example of prokaryotic differentiation and multicellular behaviour
C Allison, C Hughes
Science Progress (1933-), 403-422, 1991
2101991
Three's company: component structures bring a closer view of tripartite drug efflux pumps
J Eswaran, E Koronakis, MK Higgins, C Hughes, V Koronakis
Current opinion in structural biology 14 (6), 741-747, 2004
2082004
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