| Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications I Roeder, M Horn, I Glauche, A Hochhaus, MC Mueller, M Loeffler Nature medicine 12 (10), 1181-1184, 2006 | 411 | 2006 |
| Tissue stem cells: definition, plasticity, heterogeneity, self-organization and models–a conceptual approach M Loeffler, I Roeder Cells Tissues Organs 171 (1), 8-26, 2002 | 299 | 2002 |
| Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis A Garthe, I Roeder, G Kempermann Hippocampus 26 (2), 261-271, 2016 | 256 | 2016 |
| A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity I Roeder, M Loeffler Experimental hematology 30 (8), 853-861, 2002 | 226 | 2002 |
| High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics B Schmid, G Shah, N Scherf, M Weber, K Thierbach, CP Campos, ... Nature communications 4 (1), 2207, 2013 | 190 | 2013 |
| Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU. 1 I Roeder, I Glauche Journal of theoretical biology 241 (4), 852-865, 2006 | 172 | 2006 |
| The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis KB Schoedel, MNF Morcos, T Zerjatke, I Roeder, T Grinenko, ... Blood, The Journal of the American Society of Hematology 128 (19), 2285-2296, 2016 | 128 | 2016 |
| Nanog variability and pluripotency regulation of embryonic stem cells-insights from a mathematical model analysis I Glauche, M Herberg, I Roeder PloS one 5 (6), e11238, 2010 | 121 | 2010 |
| Stem cell proliferation and quiescence—two sides of the same coin I Glauche, K Moore, L Thielecke, K Horn, M Loeffler, I Roeder PLoS computational biology 5 (7), e1000447, 2009 | 117 | 2009 |
| Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization I Roeder, LM Kamminga, K Braesel, B Dontje, G de Haan, M Loeffler Blood 105 (2), 609-616, 2005 | 99 | 2005 |
| Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications I Glauche, M Cross, M Loeffler, I Roeder Stem cells 25 (7), 1791-1799, 2007 | 98 | 2007 |
| Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia M Horn, I Glauche, MC Müller, R Hehlmann, A Hochhaus, M Loeffler, ... Blood, The Journal of the American Society of Hematology 121 (2), 378-384, 2013 | 84 | 2013 |
| Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells OS Kustikova, A Schwarzer, M Stahlhut, MH Brugman, T Neumann, ... Leukemia 27 (5), 1127-1138, 2013 | 77 | 2013 |
| Whither systems medicine? R Apweiler, T Beissbarth, MR Berthold, N Blüthgen, Y Burmeister, ... Experimental & molecular medicine 50 (3), e453-e453, 2018 | 76 | 2018 |
| Multiplexing clonality: combining RGB marking and genetic barcoding K Cornils, L Thielecke, S Hüser, M Forgber, M Thomaschewski, N Kleist, ... Nucleic acids research 42 (7), e56-e56, 2014 | 76 | 2014 |
| Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: a simulation study based on phase III trial data AC Fassoni, C Baldow, I Roeder, I Glauche Haematologica 103 (11), 1825, 2018 | 67 | 2018 |
| In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells NM Rashidi, MK Scott, N Scherf, A Krinner, JS Kalchschmidt, K Gounaris, ... Blood, The Journal of the American Society of Hematology 124 (1), 79-83, 2014 | 66 | 2014 |
| Insertional mutagenesis and clonal dominance: biological and statistical considerations B Fehse, I Roeder Gene therapy 15 (2), 143-153, 2008 | 66 | 2008 |
| Heparin modification of a biomimetic bone matrix for controlled release of VEGF S Knaack, A Lode, B Hoyer, A Rösen‐Wolff, A Gabrielyan, I Roeder, ... Journal of Biomedical Materials Research Part A 102 (10), 3500-3511, 2014 | 63 | 2014 |
| Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach I Roeder, K Horn, HB Sieburg, R Cho, C Muller-Sieburg, M Loeffler Blood, The Journal of the American Society of Hematology 112 (13), 4874-4883, 2008 | 63 | 2008 |
