It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS R Ramanathan, M Jemal, S Ramagiri, YQ Xia, WG Humpreys, T Olah, ... Journal of mass spectrometry 46 (6), 595-601, 2011 | 200 | 2011 |
Liquid Chromatography/Mass Spectrometry Methods for Distinguishing N-Oxides from Hydroxylated Compounds R Ramanathan, AD Su, N Alvarez, N Blumenkrantz, SK Chowdhury, ... Analytical chemistry 72 (6), 1352-1359, 2000 | 158 | 2000 |
In electrospray ionization source hydrogen/deuterium exchange LC-MS and LC-MS/MS for characterization of metabolites W Lam, R Ramanathan Journal of the American Society for Mass Spectrometry 13 (4), 345-353, 2002 | 144 | 2002 |
Structure and fragmentation mechanisms of isomeric T-rich oligodeoxynucleotides: a comparison of four tandem mass spectrometric methods Z Wang, KX Wan, R Ramanathan, JS Taylor, ML Gross Journal of the American Society for Mass Spectrometry 9 (7), 683-691, 1998 | 113 | 1998 |
Dose‐dependent inhibition of OATP1B by rifampicin in healthy volunteers: comprehensive evaluation of candidate biomarkers and OATP1B probe drugs D Mori, E Kimoto, B Rago, Y Kondo, A King‐Ahmad, R Ramanathan, ... Clinical Pharmacology & Therapeutics 107 (4), 1004-1013, 2020 | 81 | 2020 |
Response normalized liquid chromatography nanospray ionization mass spectrometry R Ramanathan, R Zhong, N Blumenkrantz, SK Chowdhury, KB Alton Journal of the American society for mass spectrometry 18, 1891-1899, 2007 | 75 | 2007 |
Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist A Ghosal, X Lu, N Penner, L Gao, R Ramanathan, SK Chowdhury, ... Drug metabolism and disposition 39 (1), 30-38, 2011 | 61 | 2011 |
Mass spectrometry in drug metabolism and pharmacokinetics R Ramanathan John Wiley & Sons, 2011 | 59 | 2011 |
Metabolism of loratadine and further characterization of its in vitro metabolites A Ghosal, S Gupta, R Ramanathan, Y Yuan, X Lu, ADI Su, N Alvarez, ... Drug metabolism letters 3 (3), 162-170, 2009 | 56 | 2009 |
Quantitative determination of hippuric and benzoic acids in urine by LC–MS/MS using surrogate standards N Penner, R Ramanathan, J Zgoda-Pols, S Chowdhury Journal of pharmaceutical and biomedical analysis 52 (4), 534-543, 2010 | 55 | 2010 |
Novel MS solutions inspired by MIST R Ramanathan, JL Josephs, M Jemal, M Arnold, WG Humphreys Bioanalysis 2 (7), 1291-1313, 2010 | 49 | 2010 |
Disposition of loratadine in healthy volunteers R Ramanathan, L Reyderman, K Kulmatycki, AD Su, N Alvarez, ... Xenobiotica 37 (7), 753-769, 2007 | 47 | 2007 |
Distinguishing N‐oxide and hydroxyl compounds: impact of heated capillary/heated ion transfer tube in inducing atmospheric pressure ionization source … DM Peiris, W Lam, S Michael, R Ramanathan Journal of mass spectrometry 39 (6), 600-606, 2004 | 44 | 2004 |
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV)(Part 1–small molecules, peptides and small molecule biomarkers by LCMS) E Yang, J Welink, S Cape, E Woolf, J Sydor, C James, D Goykhman, ... Bioanalysis 8 (22), 2363-2378, 2016 | 42 | 2016 |
Disposition of desloratadine in healthy volunteers R Ramanathan, L Reyderman, AD Su, N Alvarez, SK Chowdhury, ... Xenobiotica 37 (7), 770-787, 2007 | 40 | 2007 |
Identification of appropriate endogenous biomarker for risk assessment of multidrug and toxin extrusion protein‐mediated drug‐drug interactions in healthy volunteers T Miyake, E Kimoto, L Luo, S Mathialagan, LM Horlbogen, R Ramanathan, ... Clinical Pharmacology & Therapeutics 109 (2), 507-516, 2021 | 37 | 2021 |
2017 White Paper on recent issues in bioanalysis: aren't BMV guidance/guidelines ‘Scientific’? (Part 1 – LCMS: small molecules, peptides and small molecule … J Welink, E Yang, N Hughes, B Rago, E Woolf, J Sydor, L Coppola, ... Bioanalysis 9 (22), 1807-1825, 2017 | 37 | 2017 |
Metabolism and excretion of loratadine in male and female mice, rats and monkeys R Ramanathan, N Alvarez, AD Su, S Chowdhury, K Alton, K Stauber, ... Xenobiotica 35 (2), 155-189, 2005 | 37 | 2005 |
Identification of glycochenodeoxycholate 3‐O‐glucuronide and glycodeoxycholate 3‐O‐glucuronide as highly sensitive and specific OATP1B1 biomarkers M Neuvonen, P Hirvensalo, A Tornio, B Rago, M West, S Lazzaro, ... Clinical Pharmacology & Therapeutics 109 (3), 646-657, 2021 | 36 | 2021 |
2018 White Paper on Recent Issues in Bioanalysis: ‘A Global Bioanalytical Community Perspective on Last Decade of Incurred Samples Reanalysis (ISR)’ (Part 1 … J Welink, Y Xu, E Yang, A Wilson, N Henderson, L Luo, S Fraser, U Kavita, ... Bioanalysis 10 (22), 1781-1801, 2018 | 36 | 2018 |