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Ragu Ramanathan
Ragu Ramanathan
Pharmaron
在 pharmaron.com 的电子邮件经过验证
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It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS
R Ramanathan, M Jemal, S Ramagiri, YQ Xia, WG Humpreys, T Olah, ...
Journal of mass spectrometry 46 (6), 595-601, 2011
2002011
Liquid Chromatography/Mass Spectrometry Methods for Distinguishing N-Oxides from Hydroxylated Compounds
R Ramanathan, AD Su, N Alvarez, N Blumenkrantz, SK Chowdhury, ...
Analytical chemistry 72 (6), 1352-1359, 2000
1582000
In electrospray ionization source hydrogen/deuterium exchange LC-MS and LC-MS/MS for characterization of metabolites
W Lam, R Ramanathan
Journal of the American Society for Mass Spectrometry 13 (4), 345-353, 2002
1442002
Structure and fragmentation mechanisms of isomeric T-rich oligodeoxynucleotides: a comparison of four tandem mass spectrometric methods
Z Wang, KX Wan, R Ramanathan, JS Taylor, ML Gross
Journal of the American Society for Mass Spectrometry 9 (7), 683-691, 1998
1131998
Dose‐dependent inhibition of OATP1B by rifampicin in healthy volunteers: comprehensive evaluation of candidate biomarkers and OATP1B probe drugs
D Mori, E Kimoto, B Rago, Y Kondo, A King‐Ahmad, R Ramanathan, ...
Clinical Pharmacology & Therapeutics 107 (4), 1004-1013, 2020
812020
Response normalized liquid chromatography nanospray ionization mass spectrometry
R Ramanathan, R Zhong, N Blumenkrantz, SK Chowdhury, KB Alton
Journal of the American society for mass spectrometry 18, 1891-1899, 2007
752007
Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist
A Ghosal, X Lu, N Penner, L Gao, R Ramanathan, SK Chowdhury, ...
Drug metabolism and disposition 39 (1), 30-38, 2011
612011
Mass spectrometry in drug metabolism and pharmacokinetics
R Ramanathan
John Wiley & Sons, 2011
592011
Metabolism of loratadine and further characterization of its in vitro metabolites
A Ghosal, S Gupta, R Ramanathan, Y Yuan, X Lu, ADI Su, N Alvarez, ...
Drug metabolism letters 3 (3), 162-170, 2009
562009
Quantitative determination of hippuric and benzoic acids in urine by LC–MS/MS using surrogate standards
N Penner, R Ramanathan, J Zgoda-Pols, S Chowdhury
Journal of pharmaceutical and biomedical analysis 52 (4), 534-543, 2010
552010
Novel MS solutions inspired by MIST
R Ramanathan, JL Josephs, M Jemal, M Arnold, WG Humphreys
Bioanalysis 2 (7), 1291-1313, 2010
492010
Disposition of loratadine in healthy volunteers
R Ramanathan, L Reyderman, K Kulmatycki, AD Su, N Alvarez, ...
Xenobiotica 37 (7), 753-769, 2007
472007
Distinguishing N‐oxide and hydroxyl compounds: impact of heated capillary/heated ion transfer tube in inducing atmospheric pressure ionization source …
DM Peiris, W Lam, S Michael, R Ramanathan
Journal of mass spectrometry 39 (6), 600-606, 2004
442004
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV)(Part 1–small molecules, peptides and small molecule biomarkers by LCMS)
E Yang, J Welink, S Cape, E Woolf, J Sydor, C James, D Goykhman, ...
Bioanalysis 8 (22), 2363-2378, 2016
422016
Disposition of desloratadine in healthy volunteers
R Ramanathan, L Reyderman, AD Su, N Alvarez, SK Chowdhury, ...
Xenobiotica 37 (7), 770-787, 2007
402007
Identification of appropriate endogenous biomarker for risk assessment of multidrug and toxin extrusion protein‐mediated drug‐drug interactions in healthy volunteers
T Miyake, E Kimoto, L Luo, S Mathialagan, LM Horlbogen, R Ramanathan, ...
Clinical Pharmacology & Therapeutics 109 (2), 507-516, 2021
372021
2017 White Paper on recent issues in bioanalysis: aren't BMV guidance/guidelines ‘Scientific’? (Part 1 – LCMS: small molecules, peptides and small molecule …
J Welink, E Yang, N Hughes, B Rago, E Woolf, J Sydor, L Coppola, ...
Bioanalysis 9 (22), 1807-1825, 2017
372017
Metabolism and excretion of loratadine in male and female mice, rats and monkeys
R Ramanathan, N Alvarez, AD Su, S Chowdhury, K Alton, K Stauber, ...
Xenobiotica 35 (2), 155-189, 2005
372005
Identification of glycochenodeoxycholate 3‐O‐glucuronide and glycodeoxycholate 3‐O‐glucuronide as highly sensitive and specific OATP1B1 biomarkers
M Neuvonen, P Hirvensalo, A Tornio, B Rago, M West, S Lazzaro, ...
Clinical Pharmacology & Therapeutics 109 (3), 646-657, 2021
362021
2018 White Paper on Recent Issues in Bioanalysis: ‘A Global Bioanalytical Community Perspective on Last Decade of Incurred Samples Reanalysis (ISR)’ (Part 1 …
J Welink, Y Xu, E Yang, A Wilson, N Henderson, L Luo, S Fraser, U Kavita, ...
Bioanalysis 10 (22), 1781-1801, 2018
362018
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