| Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage JP Zhang, XL Li, GH Li, W Chen, C Arakaki, GD Botimer, D Baylink, ... Genome biology 18, 1-18, 2017 | 510 | 2017 |
| HIF-1α inhibition ameliorates neonatal brain injury in a rat pup hypoxic–ischemic model W Chen, V Jadhav, J Tang, JH Zhang Neurobiology of disease 31 (3), 433-441, 2008 | 160 | 2008 |
| Arteriovenous malformation in the adult mouse brain resembling the human disease EJ Walker, H Su, F Shen, EJ Choi, SP Oh, G Chen, MT Lawton, H Kim, ... Annals of neurology 69 (6), 954-962, 2011 | 143 | 2011 |
| Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia EJ Choi, W Chen, K Jun, HM Arthur, WL Young, H Su PloS one 9 (2), e88511, 2014 | 142 | 2014 |
| Matrix metalloproteinases inhibition provides neuroprotection against hypoxia‐ischemia in the developing brain W Chen, R Hartman, R Ayer, S Marcantonio, J Kamper, J Tang, JH Zhang Journal of neurochemistry 111 (3), 726-736, 2009 | 136 | 2009 |
| Protective effects of recombinant osteopontin on early brain injury after subarachnoid hemorrhage in rats H Suzuki, R Ayer, T Sugawara, W Chen, T Sozen, Y Hasegawa, ... Critical care medicine 38 (2), 612-618, 2010 | 127 | 2010 |
| Different effects of sgRNA length on CRISPR-mediated gene knockout efficiency JP Zhang, XL Li, A Neises, W Chen, LP Hu, GZ Ji, JY Yu, J Xu, WP Yuan, ... Scientific reports 6 (1), 28566, 2016 | 122 | 2016 |
| Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression XL Li, GH Li, J Fu, YW Fu, L Zhang, W Chen, C Arakaki, JP Zhang, W Wen, ... Nucleic acids research 46 (19), 10195-10215, 2018 | 116 | 2018 |
| Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice Q Ma, A Manaenko, NH Khatibi, W Chen, JH Zhang, J Tang Journal of Cerebral Blood Flow & Metabolism 31 (3), 881-893, 2011 | 113 | 2011 |
| Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats T Lekic, R Hartman, H Rojas, A Manaenko, W Chen, R Ayer, J Tang, ... Journal of neurotrauma 27 (3), 627-637, 2010 | 112 | 2010 |
| Reduced Mural Cell Coverage and Impaired Vessel Integrity After Angiogenic Stimulation in the Alk1-deficient Brain W Chen, Y Guo, EJ Walker, F Shen, K Jun, SP Oh, V Degos, MT Lawton, ... Arteriosclerosis, thrombosis, and vascular biology 33 (2), 305-310, 2013 | 111 | 2013 |
| Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury W Chen, RP Ostrowski, A Obenaus, JH Zhang Experimental neurology 216 (1), 7-15, 2009 | 110 | 2009 |
| Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase T Sugawara, R Ayer, V Jadhav, W Chen, T Tsubokawa, JH Zhang Journal of neuroscience research 86 (16), 3635-3643, 2008 | 108 | 2008 |
| Computational molecular docking and virtual screening revealed promising SARS-CoV-2 drugs M Hosseini, W Chen, D Xiao, C Wang Precision clinical medicine 4 (1), 1-16, 2021 | 107 | 2021 |
| Osteopontin reduced hypoxia–ischemia neonatal brain injury by suppression of apoptosis in a rat pup model W Chen, Q Ma, H Suzuki, R Hartman, J Tang, JH Zhang Stroke 42 (3), 764-769, 2011 | 94 | 2011 |
| Ac-YVAD-CMK decreases blood–brain barrier degradation by inhibiting caspase-1 activation of interleukin-1β in intracerebral hemorrhage mouse model B Wu, Q Ma, N Khatibi, W Chen, T Sozen, O Cheng, J Tang Translational stroke research 1, 57-64, 2010 | 94 | 2010 |
| Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing W Xiao, L Ren, Z Chen, LT Fang, Y Zhao, J Lack, M Guan, B Zhu, ... Nature biotechnology 39 (9), 1141-1150, 2021 | 91 | 2021 |
| Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats T Sugawara, V Jadhav, R Ayer, W Chen, H Suzuki, JH Zhang Stroke 40 (4), 1530-1532, 2009 | 91 | 2009 |
| Brain arteriovenous malformation modeling, pathogenesis, and novel therapeutic targets W Chen, EJ Choi, CM McDougall, H Su Translational stroke research 5, 316-329, 2014 | 90 | 2014 |
| De Novo Cerebrovascular Malformation in the Adult Mouse After Endothelial Alk1 Deletion and Angiogenic Stimulation W Chen, Z Sun, Z Han, K Jun, M Camus, M Wankhede, L Mao, T Arnold, ... Stroke 45 (3), 900-902, 2014 | 90 | 2014 |
