CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity Á Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz, A Cirella, C de Andrea, ... Immunity 52 (5), 856-871. e8, 2020 | 517 | 2020 |
IL8, neutrophils, and NETs in a collusion against cancer immunity and immunotherapy A Teijeira, S Garasa, MC Ochoa, M Villalba, I Olivera, A Cirella, ... Clinical Cancer Research 27 (9), 2383-2393, 2021 | 144 | 2021 |
Novel strategies exploiting interleukin-12 in cancer immunotherapy A Cirella, C Luri-Rey, CA Di Trani, A Teijeira, I Olivera, E Bolaños, ... Pharmacology & therapeutics 239, 108189, 2022 | 57 | 2022 |
Differential Interleukin‐8 thresholds for chemotaxis and netosis in human neutrophils A Teijeira, S Garasa, MC Ochoa, A Cirella, I Olivera, J Glez‐Vaz, ... European journal of immunology 51 (9), 2274-2280, 2021 | 45 | 2021 |
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic I Etxeberria, E Bolaños, A Teijeira, S Garasa, A Yanguas, A Azpilikueta, ... Proceedings of the National Academy of Sciences 118 (26), e2025930118, 2021 | 30 | 2021 |
A therapeutically actionable protumoral axis of cytokines involving IL-8, TNFα, and IL-1β I Olivera, R Sanz-Pamplona, E Bolaños, I Rodriguez, I Etxeberria, ... Cancer discovery 12 (9), 2140-2157, 2022 | 24 | 2022 |
Advances in mRNA-based drug discovery in cancer immunotherapy CA Di Trani, M Fernandez-Sendin, A Cirella, A Segués, I Olivera, ... Expert opinion on drug discovery 17 (1), 41-53, 2022 | 23 | 2022 |
Mouse models of peritoneal carcinomatosis to develop clinical applications Á Bella, CA Di Trani, M Fernández-Sendin, L Arrizabalaga, A Cirella, ... Cancers 13 (5), 963, 2021 | 20 | 2021 |
Depletion of conventional type-1 dendritic cells in established tumors suppresses immunotherapy efficacy A Teijeira, S Garasa, C Luri-Rey, C De Andrea, M Gato, C Molina, ... Cancer research 82 (23), 4373-4385, 2022 | 19 | 2022 |
mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy I Olivera, E Bolaños, J Gonzalez-Gomariz, S Hervas-Stubbs, KV Mariño, ... Cell Reports Medicine 4 (3), 2023 | 18 | 2023 |
miR-216a acts as a negative regulator of breast cancer by modulating stemness properties and tumor microenvironment G Roscigno, A Cirella, A Affinito, C Quintavalle, I Scognamiglio, F Palma, ... International Journal of Molecular Sciences 21 (7), 2313, 2020 | 18 | 2020 |
Type 2 immunity is maintained during cancer-associated adipose tissue wasting PJ Lenehan, A Cirella, AM Uchida, SJ Crowley, T Sharova, G Boland, ... Immunotherapy Advances 1 (1), ltab011, 2021 | 15 | 2021 |
Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies J Glez-Vaz, A Azpilikueta, I Olivera, A Cirella, A Teijeira, MC Ochoa, ... Journal for ImmunoTherapy of Cancer 10 (3), 2022 | 13 | 2022 |
Intratumoral gene transfer of mRNAs encoding IL12 in combination with decoy-resistant IL18 improves local and systemic antitumor immunity A Cirella, E Bolaños, CA Di Trani, CE de Andrea, S Sánchez-Gregorio, ... Cancer Immunology Research 11 (2), 184-198, 2023 | 10 | 2023 |
Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma MC Ochoa, S Sanchez-Gregorio, CE de Andrea, S Garasa, M Alvarez, ... Cell Reports Medicine 4 (4), 2023 | 9 | 2023 |
Interleukin-12 message in a bottle A Cirella, P Berraondo, CA Di Trani, I Melero Clinical Cancer Research 26 (23), 6080-6082, 2020 | 9 | 2020 |
Overcoming the limitations of cytokines to improve cancer therapy CA Di Trani, A Cirella, L Arrizabalaga, M Fernandez-Sendin, A Bella, ... International Review of Cell and Molecular Biology 369, 107-141, 2022 | 8 | 2022 |
Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse models CA Di Trani, A Cirella, L Arrizabalaga, Á Bella, M Fernandez-Sendin, ... Oncoimmunology 12 (1), 2147317, 2023 | 7 | 2023 |
Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic M Alvarez, C Molina, S Garasa, MC Ochoa, ME Rodriguez-Ruiz, G Gomis, ... Oncoimmunology 12 (1), 2197370, 2023 | 6 | 2023 |
Intratumoral co‐injection of NK cells and NKG2A‐neutralizing monoclonal antibodies I Melero, MC Ochoa, C Molina, S Sanchez‐Gregorio, S Garasa, ... EMBO Molecular Medicine 15 (11), e17804, 2023 | 5 | 2023 |