HLA-A* 3101 and carbamazepine-induced hypersensitivity reactions in Europeans M McCormack, A Alfirevic, S Bourgeois, JJ Farrell, D Kasperavičiūtė, ... New England Journal of Medicine 364 (12), 1134-1143, 2011 | 1092 | 2011 |
Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations FF González-Galarza, LYC Takeshita, EJM Santos, F Kempson, ... Nucleic acids research 43 (D1), D784-D788, 2015 | 831 | 2015 |
Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools FF Gonzalez-Galarza, A McCabe, EJM Santos, J Jones, L Takeshita, ... Nucleic acids research 48 (D1), D783-D788, 2020 | 565 | 2020 |
HLA-B Locus in Caucasian Patients with Carbamazepine hypersensitivity A Alfirevic, AL Jorgensen, PR Williamson, DW Chadwick, BK Park, ... Pharmacogenomics 7 (6), 813-818, 2006 | 357 | 2006 |
Cost-effectiveness analysis of HLA B* 5701 genotyping in preventing abacavir hypersensitivity DA Hughes, FJ Vilar, CC Ward, A Alfirevic, BK Park, M Pirmohamed Pharmacogenetics and Genomics 14 (6), 335-342, 2004 | 350 | 2004 |
Human leukocyte antigen (HLA)‐B* 57: 01‐restricted activation of drug‐specific T cells provides the immunological basis for flucloxacillin‐induced liver injury MM Monshi, L Faulkner, A Gibson, RE Jenkins, J Farrell, CJ Earnshaw, ... Hepatology 57 (2), 727-739, 2013 | 271 | 2013 |
Phenotype standardization for statin‐induced myotoxicity A Alfirevic, D Neely, J Armitage, H Chinoy, RG Cooper, R Laaksonen, ... Clinical Pharmacology & Therapeutics 96 (4), 470-476, 2014 | 246 | 2014 |
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles JI Goldstein, L Fredrik Jarskog, C Hilliard, A Alfirevic, L Duncan, ... Nature communications 5 (1), 4757, 2014 | 183 | 2014 |
HLA genotype and carbamazepine‐induced cutaneous adverse drug reactions: a systematic review VL Yip, AG Marson, AL Jorgensen, M Pirmohamed, A Alfirevic Clinical Pharmacology & Therapeutics 92 (6), 757-765, 2012 | 175 | 2012 |
Practical recommendations for pharmacogenomics-based prescription: 2010 ESF–UB Conference on Pharmacogenetics and Pharmacogenomics L Becquemont, A Alfirevic, U Amstutz, H Brauch, E Jacqz-Aigrain, ... Pharmacogenomics 12 (1), 113-124, 2011 | 161 | 2011 |
TNF-α promoter region gene polymorphisms in HIV-positive patients with lipodystrophy B Maher, A Alfirevic, FJ Vilar, EGL Wilkins, BK Park, M Pirmohamed Aids 16 (15), 2013-2018, 2002 | 160 | 2002 |
Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population DF Carr, M Chaponda, AL Jorgensen, EC Castro, JJ van Oosterhout, ... Clinical Infectious Diseases 56 (9), 1330-1339, 2013 | 128 | 2013 |
Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity M Pirmohamed, A Alfirevic, J Vilar, A Stalford, EGL Wilkins, E Sim, ... Pharmacogenetics and Genomics 10 (8), 705-713, 2000 | 106 | 2000 |
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia SE Legge, ML Hamshere, S Ripke, AF Pardinas, JI Goldstein, E Rees, ... Molecular psychiatry 22 (10), 1502-1508, 2017 | 102 | 2017 |
Pathway analysis of genetic factors associated with spontaneous preterm birth and pre-labor preterm rupture of membranes A Capece, O Vasieva, S Meher, Z Alfirevic, A Alfirevic PloS one 9 (9), e108578, 2014 | 96 | 2014 |
Lamotrigine is a substrate for OCT1 in brain endothelial cells D Dickens, A Owen, A Alfirevic, A Giannoudis, A Davies, B Weksler, ... Biochemical pharmacology 83 (6), 805-814, 2012 | 95 | 2012 |
Effects of CYP4F2 genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy JE Zhang, AL Jorgensen, A Alfirevic, PR Williamson, CH Toh, BK Park, ... Pharmacogenetics and genomics 19 (10), 781-789, 2009 | 85 | 2009 |
In silicoanalysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers A Alfirevic, F Gonzalez-Galarza, C Bell, K Martinsson, V Platt, G Bretland, ... Genome medicine 4, 1-14, 2012 | 84 | 2012 |
Genetics of immune-mediated adverse drug reactions: a comprehensive and clinical review VLM Yip, A Alfirevic, M Pirmohamed Clinical reviews in allergy & immunology 48, 165-175, 2015 | 83 | 2015 |
Low dose aspirin and pregnancy: how important is aspirin resistance? K Navaratnam, A Alfirevic, Z Alfirevic BJOG: An International Journal of Obstetrics & Gynaecology 123 (9), 1481-1487, 2016 | 71 | 2016 |