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Extension of murine life span by overexpression of catalase targeted to mitochondria SE Schriner, NJ Linford, GM Martin, P Treuting, CE Ogburn, M Emond, ... science 308 (5730), 1909-1911, 2005 | 2044 | 2005 |
Trends in oxidative aging theories FL Muller, MS Lustgarten, Y Jang, A Richardson, H Van Remmen Free Radical Biology and Medicine 43 (4), 477-503, 2007 | 1424 | 2007 |
Complex III releases superoxide to both sides of the inner mitochondrial membrane FL Muller, Y Liu, H Van Remmen Journal of Biological Chemistry 279 (47), 49064-49073, 2004 | 1301 | 2004 |
Does oxidative damage to DNA increase with age? ML Hamilton, H Van Remmen, JA Drake, H Yang, ZM Guo, K Kewitt, ... Proceedings of the National Academy of Sciences 98 (18), 10469-10474, 2001 | 988 | 2001 |
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging H Van Remmen, Y Ikeno, M Hamilton, M Pahlavani, N Wolf, SR Thorpe, ... Physiological genomics 16 (1), 29-37, 2003 | 903 | 2003 |
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults LJ Yant, Q Ran, L Rao, H Van Remmen, T Shibatani, JG Belter, L Motta, ... Free Radical Biology and Medicine 34 (4), 496-502, 2003 | 826 | 2003 |
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life S Elchuri, TD Oberley, W Qi, RS Eisenstein, L Jackson Roberts, ... Oncogene 24 (3), 367-380, 2005 | 811 | 2005 |
Is the oxidative stress theory of aging dead? VI Pérez, A Bokov, H Van Remmen, J Mele, Q Ran, Y Ikeno, A Richardson Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1005-1014, 2009 | 724 | 2009 |
Insulin resistance is a cellular antioxidant defense mechanism KL Hoehn, AB Salmon, C Hohnen-Behrens, N Turner, AJ Hoy, ... Proceedings of the National Academy of Sciences 106 (42), 17787-17792, 2009 | 609 | 2009 |
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice MD Williams, H Van Remmen, CC Conrad, TT Huang, CJ Epstein, ... Journal of Biological Chemistry 273 (43), 28510-28515, 1998 | 550 | 1998 |
Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy FL Muller, W Song, Y Liu, A Chaudhuri, S Pieke-Dahl, R Strong, ... Free Radical Biology and Medicine 40 (11), 1993-2004, 2006 | 545 | 2006 |
Methionine oxidation and aging ER Stadtman, H Van Remmen, A Richardson, NB Wehr, RL Levine Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1703 (2), 135-140, 2005 | 485 | 2005 |
High oxidative damage levels in the longest‐living rodent, the naked mole‐rat B Andziak, TP O’Connor, W Qi, EM DeWaal, A Pierce, AR Chaudhuri, ... Aging cell 5 (6), 463-471, 2006 | 417 | 2006 |
The overexpression of major antioxidant enzymes does not extend the lifespan of mice VI Pérez, H Van Remmen, A Bokov, CJ Epstein, J Vijg, A Richardson Aging cell 8 (1), 73-75, 2009 | 411 | 2009 |
Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production FL Muller, W Song, YC Jang, Y Liu, M Sabia, A Richardson, ... American journal of physiology-Regulatory, integrative and comparative …, 2007 | 395 | 2007 |
Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? JL Styskal, H Van Remmen, A Richardson, AB Salmon Free radical biology and medicine 52 (1), 46-58, 2012 | 366 | 2012 |
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration YC Jang, MS Lustgarten, Y Liu, FL Muller, A Bhattacharya, H Liang, ... The FASEB Journal 24 (5), 1376, 2010 | 338 | 2010 |
Oxidative damage to mitochondria and aging H Van Remmen, A Richardson Experimental gerontology 36 (7), 957-968, 2001 | 324 | 2001 |
Age-associated alterations of the neuromuscular junction YC Jang, H Van Remmen Experimental gerontology 46 (2-3), 193-198, 2011 | 317 | 2011 |