Myosin sequestration regulates sarcomere function, cardiomyocyte energetics, and metabolism, informing the pathogenesis of hypertrophic cardiomyopathy CN Toepfer, AC Garfinkel, G Venturini, H Wakimoto, G Repetti, L Alamo, ... Circulation 141 (10), 828-842, 2020 | 251 | 2020 |
Synthetic biology in the clinic: engineering vaccines, diagnostics, and therapeutics X Tan, JH Letendre, JJ Collins, WW Wong Cell 184 (4), 881-898, 2021 | 114 | 2021 |
High-performance chemical-and light-inducible recombinases in mammalian cells and mice BH Weinberg, JH Cho, Y Agarwal, NTH Pham, LD Caraballo, M Walkosz, ... Nature communications 10 (1), 4845, 2019 | 61 | 2019 |
Electrospun nanofiber scaffolds and their hydrogel composites for the engineering and regeneration of soft tissues OS Manoukian, R Matta, J Letendre, P Collins, AD Mazzocca, SG Kumbar Biomedical nanotechnology: Methods and protocols, 261-278, 2017 | 42 | 2017 |
Mechanical confinement via a PEG/Collagen interpenetrating network inhibits behavior characteristic of malignant cells in the triple negative breast cancer cell line MDA. MB. 231 DS Reynolds, KM Bougher, JH Letendre, SF Fitzgerald, UO Gisladottir, ... Acta biomaterialia 77, 85-95, 2018 | 31 | 2018 |
Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals KA Kiwimagi, JH Letendre, BH Weinberg, J Wang, M Chen, L Watanabe, ... Communications biology 4 (1), 875, 2021 | 10 | 2021 |
Engineering digitizer circuits for chemical and genetic screens in human cells NM Wong, E Frias, FD Sigoillot, JH Letendre, M Hild, WW Wong Nature communications 12 (1), 6150, 2021 | 4 | 2021 |
Programmable Mixed-Signal Biocomputers in Mammalian Cells JH Letendre, BH Weinberg, M Mendes, JM Marano, KJW Benman, ... bioRxiv, 2022.06. 07.495130, 2022 | 1 | 2022 |
Intron-Mediated Enhancement of Titin (TTN) Regulates Sarcomere Formation and Function Y Kim, S Kim, M Neyazi, M Schmid, J Letendre, J Ewoldt, F Xiao, ... Circulation 144 (Suppl_1), A12802-A12802, 2021 | 1 | 2021 |
Genetic Circuit Designs to Improve Synthetic Biological Signaling in Mammalian Cells JH Letendre Boston University, 2022 | | 2022 |