Mechanismof Action and Antiviral Activity of Benzimidazole-Based AllostericInhibitors of the Hepatitis C Virus RNA-Dependent RNAPolymerase L Tomei, S Altamura, L Bartholomew, A Biroccio, A Ceccacci, L Pacini, ... Journal of virology 77 (24), 13225-13231, 2003 | 241 | 2003 |
The NS2 protein of hepatitis C virus is a transmembrane polypeptide E Santolini, L Pacini, C Fipaldini, G Migliaccio, N Monica Journal of virology 69 (12), 7461-7471, 1995 | 238 | 1995 |
In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor C Trozzi, L Bartholomew, A Ceccacci, G Biasiol, L Pacini, S Altamura, ... Journal of virology 77 (6), 3669-3679, 2003 | 161 | 2003 |
In vitro study of the NS2-3 protease of hepatitis C virus L Pieroni, E Santolini, C Fipaldini, L Pacini, G Migliaccio, N La Monica Journal of virology 71 (9), 6373-6380, 1997 | 123 | 1997 |
The Fragile X mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses A Janusz, J Miłek, M Perycz, L Pacini, C Bagni, L Kaczmarek, ... Journal of Neuroscience 33 (46), 18234-18241, 2013 | 122 | 2013 |
Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism E Rosina, B Battan, M Siracusano, L Di Criscio, F Hollis, L Pacini, ... Translational psychiatry 9 (1), 50, 2019 | 103 | 2019 |
Autism spectrum disorders: translating human deficits into mouse behavior E Pasciuto, SC Borrie, AK Kanellopoulos, AR Santos, E Cappuyns, ... Neurobiology of learning and memory 124, 71-87, 2015 | 99 | 2015 |
Protein synthesis levels are increased in a subset of individuals with fragile X syndrome S Jacquemont, L Pacini, AE Jønch, G Cencelli, I Rozenberg, Y He, ... Human molecular genetics 27 (12), 2039-2051, 2018 | 79 | 2018 |
Dysregulated ADAM10-mediated processing of APP during a critical time window leads to synaptic deficits in fragile X syndrome E Pasciuto, T Ahmed, T Wahle, F Gardoni, L D’Andrea, L Pacini, ... Neuron 87 (2), 382-398, 2015 | 74 | 2015 |
Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mouse A Filippini, D Bonini, C Lacoux, L Pacini, M Zingariello, L Sancillo, ... RNA biology 14 (11), 1580-1591, 2017 | 58 | 2017 |
Naturally Occurring Hepatitis C Virus Subgenomic Deletion Mutants Replicate Efficiently in Huh-7 Cells and Are trans-Packaged In Vitro To Generate Infectious … L Pacini, R Graziani, L Bartholomew, R De Francesco, G Paonessa Journal of virology 83 (18), 9079-9093, 2009 | 43 | 2009 |
Targeting the fibroblast growth factor receptor (FGFR) family in lung cancer L Pacini, AD Jenks, NC Lima, PH Huang Cells 10 (5), 1154, 2021 | 37 | 2021 |
Chimeric Sindbis viruses dependent on the NS3 protease of hepatitis C virus G Filocamo, L Pacini, G Migliaccio Journal of virology 71 (2), 1417-1427, 1997 | 34 | 1997 |
The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells F Zalfa, V Panasiti, S Carotti, M Zingariello, G Perrone, L Sancillo, L Pacini, ... Cell Death & Disease 8 (11), e3169-e3169, 2017 | 33 | 2017 |
Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia G Alfedi, R Luffarelli, I Condò, G Pedini, L Mannucci, DS Massaro, ... Movement Disorders 34 (3), 323-334, 2019 | 31 | 2019 |
A study of the mechanism by which some amphiphilic drugs affect human erythrocyte acetylcholinesterase activity A Spinedi, L Pacini, P Luly Biochemical Journal 261 (2), 569-573, 1989 | 30 | 1989 |
Arachidonic Acid Incorporation and Redistribution in Human Neuroblastoma (SK‐N‐BE) Cell Phospholipids A Spinedi, L Pacini, M Piacentini, G Melino, P Luly Journal of neurochemistry 54 (3), 778-782, 1990 | 27 | 1990 |
Muscarinic stimulation of SK-N-BE (2) human neuroblastoma cells elicits phosphoinositide and phosphatidylcholine hydrolysis: relationship to diacylglycerol and phosphatidic … L Pacini, C Limatola, L Frati, P Luly, A Spinedi Biochemical Journal 289 (1), 269-275, 1993 | 26 | 1993 |
A study of human erythrocyte acetylcholinesterase inhibition by chlorpromazine A Spinedi, L Pacini, C Limatola, P Luly, RN Farias Biochemical Journal 278 (2), 461-463, 1991 | 23 | 1991 |
Spatial control of nucleoporin condensation by fragile X‐related proteins A Agote‐Aran, S Schmucker, K Jerabkova, I Jmel Boyer, A Berto, L Pacini, ... The EMBO journal 39 (20), e104467, 2020 | 22 | 2020 |