Discovery of common and rare genetic risk variants for colorectal cancer JR Huyghe, SA Bien, TA Harrison, HM Kang, S Chen, SL Schmit, ... Nature genetics 51 (1), 76-87, 2019 | 498 | 2019 |
The prognostic implications of tumor infiltrating lymphocytes in colorectal cancer: a systematic review and meta-analysis GE Idos, J Kwok, N Bonthala, L Kysh, SB Gruber, C Qu Scientific reports 10 (1), 3360, 2020 | 290 | 2020 |
Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer C Müller-Tidow, R Metzger, K Kügler, S Diederichs, G Idos, M Thomas, ... Cancer research 61 (2), 647-653, 2001 | 190 | 2001 |
NCCN Guidelines® insights: genetic/familial high-risk assessment: colorectal, Version 1.2021: featured updates to the NCCN Guidelines JM Weiss, S Gupta, CA Burke, L Axell, LM Chen, DC Chung, ... Journal of the National Comprehensive Cancer Network 19 (10), 1122-1132, 2021 | 188 | 2021 |
Genome-wide association study of colorectal cancer identifies six new susceptibility loci FR Schumacher, SL Schmit, S Jiao, CK Edlund, H Wang, B Zhang, L Hsu, ... Nature communications 6 (1), 7138, 2015 | 188 | 2015 |
Novel common genetic susceptibility loci for colorectal cancer SL Schmit, CK Edlund, FR Schumacher, J Gong, TA Harrison, JR Huyghe, ... JNCI: Journal of the National Cancer Institute 111 (2), 146-157, 2019 | 178 | 2019 |
Shared heritability and functional enrichment across six solid cancers X Jiang, HK Finucane, FR Schumacher, SL Schmit, JP Tyrer, Y Han, ... Nature communications 10 (1), 431, 2019 | 129 | 2019 |
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries C Fernandez-Rozadilla, M Timofeeva, Z Chen, P Law, M Thomas, ... Nature genetics 55 (1), 89-99, 2023 | 117 | 2023 |
Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent C Müller, C Readhead, S Diederichs, G Idos, R Yang, N Tidow, H Serve, ... Molecular and cellular biology, 2000 | 107 | 2000 |
Identification of interaction partners and substrates of the cyclin A1-CDK2 complex S Diederichs, N Bäumer, P Ji, SK Metzelder, GE Idos, T Cauvet, ... Journal of Biological Chemistry 279 (32), 33727-33741, 2004 | 87 | 2004 |
Increased yield of actionable mutations using multi-gene panels to assess hereditary cancer susceptibility in an ethnically diverse clinical cohort C Ricker, JO Culver, K Lowstuter, D Sturgeon, JD Sturgeon, CR Chanock, ... Cancer genetics 209 (4), 130-137, 2016 | 85 | 2016 |
Lynch syndrome G Idos, L Valle | 78 | 2021 |
Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the US Multi-Society Task Force on Colorectal Cancer CR Boland, GE Idos, C Durno, FM Giardiello, JC Anderson, CA Burke, ... Gastroenterology 162 (7), 2063-2085, 2022 | 77 | 2022 |
Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function C Müller-Tidow, W Wang, GE Idos, S Diederichs, R Yang, C Readhead, ... Blood, The Journal of the American Society of Hematology 97 (7), 2091-2097, 2001 | 71 | 2001 |
c-myb transactivates the human cyclin A1 promoter and induces cyclin A1 gene expression C Müller, R Yang, G Idos, N Tidow, S Diederichs, OM Koch, W Verbeek, ... Blood, The Journal of the American Society of Hematology 94 (12), 4255-4262, 1999 | 63 | 1999 |
Genetic markers of malignant transformation in intraductal papillary mucinous neoplasm of the pancreas: a meta-analysis S Nissim, GE Idos, B Wu Pancreas 41 (8), 1195-1205, 2012 | 57 | 2012 |
Unexpected CDH1 Mutations Identified on Multigene Panels Pose Clinical Management Challenges K Lowstuter, CR Espenschied, D Sturgeon, C Ricker, R Karam, H LaDuca, ... JCO Precision Oncology 1, 1-12, 2017 | 56 | 2017 |
RARβ2 is a candidate tumor suppressor gene in myelofibrosis with myeloid metaplasia LC Jones, A Tefferi, GE Idos, T Kumagai, WK Hofmann, HP Koeffler Oncogene 23 (47), 7846-7853, 2004 | 56 | 2004 |
Cloning of the cyclin A1 genomic structure and characterization of the promoter region: GC boxes are essential for cell cycle-regulated transcription of the cyclin A1 gene C Müller, R Yang, L Beck-von-Peccoz, G Idos, W Verbeek, HP Koeffler Journal of Biological Chemistry 274 (16), 11220-11228, 1999 | 56 | 1999 |
Novel circulating tumor cell assay for detection of colorectal adenomas and cancer WS Tsai, JF You, HY Hung, PS Hsieh, B Hsieh, HJ Lenz, G Idos, ... Clinical and translational gastroenterology 10 (10), e00088, 2019 | 55 | 2019 |