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Karishma Dhuri
Karishma Dhuri
在 abbvie.com 的电子邮件经过验证
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Antisense oligonucleotides: an emerging area in drug discovery and development
K Dhuri, C Bechtold, E Quijano, H Pham, A Gupta, A Vikram, R Bahal
Journal of clinical medicine 9 (6), 2004, 2020
4062020
Role of lipid-based and polymer-based non-viral vectors in nucleic acid delivery for next-generation gene therapy
A Wahane, A Waghmode, A Kapphahn, K Dhuri, A Gupta, R Bahal
Molecules 25 (12), 2866, 2020
1812020
Nanoparticle delivered anti-miR-141-3p for stroke therapy
K Dhuri, RN Vyas, L Blumenfeld, R Verma, R Bahal
Cells 10 (5), 1011, 2021
402021
Therapeutic potential of chemically modified, synthetic, triplex peptide nucleic acid–based oncomir inhibitors for cancer therapy
K Dhuri, RR Gaddam, A Vikram, FJ Slack, R Bahal
Cancer research 81 (22), 5613-5624, 2021
262021
Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice
RR Gaddam, VP Jacobsen, YR Kim, M Gabani, JS Jacobs, K Dhuri, ...
Scientific reports 10 (1), 10065, 2020
152020
γ peptide nucleic acid-based miR-122 inhibition rescues vascular endothelial dysfunction in mice fed a high-fat diet
RR Gaddam, K Dhuri, YR Kim, JS Jacobs, V Kumar, Q Li, K Irani, R Bahal, ...
Journal of medicinal chemistry 65 (4), 3332-3342, 2022
102022
Simultaneous targeting of multiple oncomiRs with phosphorothioate or PNA-based anti-miRs in lymphoma cell lines
K Dhuri, SP Pradeep, J Shi, E Anastasiadou, FJ Slack, A Gupta, X Zhong, ...
Pharmaceutical research 39 (11), 2709-2720, 2022
82022
An Emerging Area in Drug Discovery and Development., 2020, 9, 2004
K Dhuri, C Bechtold, E Quijano, H Pham, A Gupta, A Vikram, ...
DOI: https://doi. org/10.3390/jcm9062004, 0
8
Head-to-head comparison of in vitro and in vivo efficacy of pHLIP-conjugated anti-seed gamma peptide nucleic acids
K Dhuri, T Duran, B Chaudhuri, FJ Slack, A Vikram, PM Glazer, R Bahal
Cell Reports Physical Science 4 (10), 2023
42023
Serine-γPNA, Invader probes, and chimeras thereof: Three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA
RG Emehiser, K Dhuri, C Shepard, S Karmakar, R Bahal, PJ Hrdlicka
Organic & biomolecular chemistry 20 (44), 8714-8724, 2022
32022
Exploring the therapeutic potential of sγPNA-141: Pharmacodynamics and mechanistic insights during ischemic stroke recovery
SK Yadav, K Dhuri, D Gamiotea-Turro, MK Cormier, V Patel, AK Yadawa, ...
Molecular Therapy Nucleic Acids 35 (4), 2024
2024
Abstract We129: Endothelium-Targeted MiR-122 Inhibition Improves Vascular Endothelial Function In a High-Fat Diet Fed mice
R Gaddam, K Dhuri, M Pathuri, V Amalkar, YRAE Kim, J Jacobs, VK Sali, ...
Circulation Research 135 (Suppl_1), AWe129-AWe129, 2024
2024
Abstract WP315: Pharmacological Validation of Advanced Gamma Peptide Nucleic Acid (PNA) Based miR Inhibitors for Ischemic Stroke Treatment
SK Yadav, D Gamiotea Turro, V Patel, K Dhuri, R Bahal, R Verma
Stroke 55 (Suppl_1), AWP315-AWP315, 2024
2024
Methods and compositions comprising therapeutic gamma peptide nucleic acid-based molecules
A Vikram, K Irani, RR Gaddam, R Bahal, K Dhuri
US Patent App. 18/165,809, 2023
2023
Next Generation Oncogenic MicroRNAs Inhibitors for Cancer Therapeutics
A Gupta, F Iqbal, K Dhuri, R Bahal
American Journal of Pharmaceutical Education 87 (8), 100156, 2023
2023
Abstract P3013: MicroRNA-122 Targeting With Gamma Peptide Nucleic Acid Inhibitor Improves Vascular Endothelial Dysfunction In Pre-diabetic Mice.
RR Gaddam, K Dhuri, YR Kim, JS Jacobs, V Kumar, Q Li, K Irani, R Bahal, ...
Circulation Research 131 (Suppl_1), AP3013-AP3013, 2022
2022
MicroRNA-122 Targeting With Gamma Peptide Nucleic Acid Inhibitor Improves Vascular Endothelial Dysfunction In Pre-diabetic Mice.
RR Gaddam, K Dhuri, YR Kim, JS Jacobs, V Kumar, Q Li, K Irani, R Bahal, ...
CIRCULATION RESEARCH 131, 2022
2022
Abstract P774: Therapeutic Efficacy of Next Generation Anti-miR-141-3p for Ischemic Stroke
K Dhuri, L Blumenfeld, R Bahal, R Verma
Stroke 52 (Suppl_1), AP774-AP774, 2021
2021
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