| Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b E Kyriakis, GA Stravodimos, AL Kantsadi, DSM Chatzileontiadou, ... FEBS letters 589 (15), 1787-1794, 2015 | 66 | 2015 |
| Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase AL Kantsadi, A Apostolou, S Theofanous, GA Stravodimos, E Kyriakis, ... Food and chemical toxicology 67, 35-43, 2014 | 60 | 2014 |
| Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver … AL Kantsadi, É Bokor, S Kun, GA Stravodimos, DSM Chatzileontiadou, ... European Journal of Medicinal Chemistry 123, 737-745, 2016 | 53 | 2016 |
| Phytogenic polyphenols as glycogen phosphorylase inhibitors: the potential of triterpenes and flavonoids for glycaemic control in type 2 diabetes G A Stravodimos, B A Chetter, E Kyriakis, A L Kantsadi, ... Current medicinal chemistry 24 (4), 384-403, 2017 | 49 | 2017 |
| A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1, 2, 4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and … S Kun, J Begum, E Kyriakis, ECV Stamati, TA Barkas, E Szennyes, ... European journal of medicinal chemistry 147, 266-278, 2018 | 31 | 2018 |
| Oxidation of human serum albumin exhibits inter-individual variability after an ultra-marathon mountain race Y Spanidis, A Priftis, D Stagos, GA Stravodimos, DD Leonidas, ... Experimental and therapeutic medicine 13 (5), 2382-2390, 2017 | 30 | 2017 |
| Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors E Kyriakis, TGA Solovou, S Kun, K Czifrák, B Szőcs, L Juhász, É Bokor, ... Bioorganic chemistry 77, 485-493, 2018 | 28 | 2018 |
| Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography … E Bokor, E Kyriakis, TGA Solovou, C Koppany, AL Kantsadi, KE Szabo, ... Journal of medicinal chemistry 60 (22), 9251-9262, 2017 | 25 | 2017 |
| van der Waals interactions govern C-β-D-glucopyranosyl triazoles’ nM inhibitory potency in human liver glycogen phosphorylase AL Kantsadi, GA Stravodimos, E Kyriakis, DSM Chatzileontiadou, ... Journal of Structural Biology 199 (1), 57-67, 2017 | 20 | 2017 |
| The ammonium sulfate inhibition of human angiogenin DSM Chatzileontiadou, VG Tsirkone, K Dossi, AG Kassouni, PGV Liggri, ... FEBS letters 590 (17), 3005-3018, 2016 | 18 | 2016 |
| Glucopyranosylidene-spiro-imidazolinones, a new ring system: synthesis and evaluation as glycogen phosphorylase inhibitors by enzyme kinetics and x-ray crystallography KE Szabó, E Kyriakis, AMG Psarra, AG Karra, Á Sipos, T Docsa, ... Journal of Medicinal Chemistry 62 (13), 6116-6136, 2019 | 16 | 2019 |
| Glycogen phosphorylase revisited: extending the resolution of the R-and T-state structures of the free enzyme and in complex with allosteric activators DD Leonidas, SE Zographos, KE Tsitsanou, VT Skamnaki, G Stravodimos, ... Acta Crystallographica Section F: Structural Biology Communications 77 (9 …, 2021 | 14 | 2021 |
| High consistency of structure-based design and X-Ray crystallography: design, synthesis, kinetic evaluation and crystallographic binding mode determination of biphenyl-N-acyl-β … T Fischer, SM Koulas, AS Tsagkarakou, E Kyriakis, GA Stravodimos, ... Molecules 24 (7), 1322, 2019 | 14 | 2019 |
| AtHESPERIN: a novel regulator of circadian rhythms with poly (A)-degrading activity in plants C Delis, A Krokida, A Tomatsidou, D Tsikou, RAA Beta, M Tsioumpekou, ... RNA biology 13 (1), 68-82, 2016 | 14 | 2016 |
| Affinity crystallography reveals the bioactive compounds of industrial juicing byproducts of Punica granatum for glycogen phosphorylase GA Stravodimos, AL Kantsadi, A Apostolou, E Kyriakis, VN Kafaski-Kanelli, ... Current drug discovery technologies 15 (1), 41-53, 2018 | 8 | 2018 |
| Glycogen phosphorylase as a target for type 2 diabetes: Synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(β-D-glucopyranosyl) urea inhibitors A L Kantsadi, V Parmenopoulou, D N Bakalov, L Snelgrove, ... Current Topics in Medicinal Chemistry 15 (23), 2373-2389, 2015 | 4 | 2015 |
| The druggability of the ATP binding site of glycogen phosphorylase kinase probed by coumarin analogues S Alexopoulos, A Gkouskou, G Stravodimos, AS Tsagkarakou, I Tsialtas, ... Current Research in Chemical Biology 2, 100022, 2022 | 3 | 2022 |
| Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its’ potential against … RT Mathomes, SM Koulas, I Tsialtas, G Stravodimos, PJ Welsby, ... Chemico-biological interactions 382, 110568, 2023 | 2 | 2023 |
| Biochemical and Structural Studies of LjSK1, a Lotus japonicus GSK3β/SHAGGY-like Kinase, Reveal Its Functional Role TGA Solovou, G Stravodimos, GE Papadopoulos, VT Skamnaki, ... Journal of Agricultural and Food Chemistry 72 (7), 3763-3772, 2024 | | 2024 |
| Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds L Lázár, AS Tsagkarakou, G Stravodimos, G Kontopidis, H Leffler, ... Journal of Medicinal Chemistry 66 (17), 12420-12431, 2023 | | 2023 |
Demetres LeonidasProfessor of Biochemistry, Department of Biochemistry and Biotechnology, University of Thessaly在 bio.uth.gr 的电子邮件经过验证
