Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia X Ma, M Edmonson, D Yergeau, DM Muzny, OA Hampton, M Rusch, ... Nature communications 6 (1), 6604, 2015 | 458 | 2015 |
Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis R Chakraborty, OA Hampton, X Shen, SJ Simko, A Shih, H Abhyankar, ... Blood, The Journal of the American Society of Hematology 124 (19), 3007-3015, 2014 | 437 | 2014 |
A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor S Gadd, V Huff, AL Walz, AHAG Ooms, AE Armstrong, DS Gerhard, ... Nature genetics 49 (10), 1487-1494, 2017 | 309 | 2017 |
Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors AL Walz, A Ooms, S Gadd, DS Gerhard, MA Smith, JMG Auvil, ... Cancer cell 27 (2), 286-297, 2015 | 302 | 2015 |
ReadDepth: a parallel R package for detecting copy number alterations from short sequencing reads CA Miller, O Hampton, C Coarfa, A Milosavljevic PloS one 6 (1), e16327, 2011 | 272 | 2011 |
Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups P Sumazin, Y Chen, LR Treviño, SF Sarabia, OA Hampton, K Patel, ... Hepatology 65 (1), 104-121, 2017 | 200 | 2017 |
Genomic profiling of pediatric acute myeloid leukemia reveals a changing mutational landscape from disease diagnosis to relapse JE Farrar, HL Schuback, RE Ries, D Wai, OA Hampton, LR Trevino, ... Cancer research 76 (8), 2197-2205, 2016 | 161 | 2016 |
Assessing structural variation in a personal genome—towards a human reference diploid genome AC English, WJ Salerno, OA Hampton, C Gonzaga-Jauregui, S Ambreth, ... BMC genomics 16, 1-15, 2015 | 160 | 2015 |
Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis R Chakraborty, TM Burke, OA Hampton, DJ Zinn, KPH Lim, H Abhyankar, ... Blood, The Journal of the American Society of Hematology 128 (21), 2533-2537, 2016 | 152 | 2016 |
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome OA Hampton, P Den Hollander, CA Miller, DA Delgado, J Li, C Coarfa, ... Genome research 19 (2), 167-177, 2009 | 150 | 2009 |
Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney A Roy, V Kumar, B Zorman, E Fang, KM Haines, HV Doddapaneni, ... Nature communications 6 (1), 8891, 2015 | 146 | 2015 |
Ampullary cancers harbor ELF3 tumor suppressor gene mutations and exhibit frequent WNT dysregulation MC Gingras, KR Covington, DK Chang, LA Donehower, AJ Gill, ... Cell reports 14 (4), 907-919, 2016 | 129 | 2016 |
Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group AHAG Ooms, S Gadd, DS Gerhard, MA Smith, JM Guidry Auvil, ... Clinical Cancer Research 22 (22), 5582-5591, 2016 | 106 | 2016 |
Functional annotation of ESR1 gene fusions in estrogen receptor-positive breast cancer JT Lei, J Shao, J Zhang, M Iglesia, DW Chan, J Cao, M Anurag, P Singh, ... Cell reports 24 (6), 1434-1444. e7, 2018 | 105 | 2018 |
MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours EJ Perlman, S Gadd, ST Arold, A Radhakrishnan, DS Gerhard, ... Nature communications 6 (1), 10013, 2015 | 85 | 2015 |
Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673 MA Smith, OA Hampton, CP Reynolds, MH Kang, JM Maris, R Gorlick, ... Pediatric blood & cancer 62 (1), 91-98, 2015 | 84 | 2015 |
Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer B Bissig-Choisat, C Kettlun-Leyton, XD Legras, B Zorman, M Barzi, ... Journal of hepatology 65 (2), 325-333, 2016 | 68 | 2016 |
Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma R Chakraborty, OA Hampton, H Abhyankar, DJ Zinn, A Grimes, B Skull, ... Oncotarget 8 (28), 46065, 2017 | 32 | 2017 |
Long-range massively parallel mate pair sequencing detects distinct mutations and similar patterns of structural mutability in two breast cancer cell lines OA Hampton, CA Miller, M Koriabine, J Li, P Den Hollander, L Carbone, ... Cancer genetics 204 (8), 447-457, 2011 | 28 | 2011 |
Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions B Gao, C Huang, K Kernstine, V Pelekanou, Y Kluger, T Jiang, ... Oncotarget 8 (7), 11114, 2017 | 23 | 2017 |