Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ... Science 357 (6357), 1255-1261, 2017 | 742 | 2017 |
Mitochondria: the calcium connection L Contreras, I Drago, E Zampese, T Pozzan Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 607-618, 2010 | 452 | 2010 |
Disruption of mitochondrial complex I induces progressive parkinsonism P González-Rodríguez, E Zampese, KA Stout, JN Guzman, E Ilijic, B Yang, ... Nature 599 (7886), 650-656, 2021 | 326 | 2021 |
Presenilin 2 modulates endoplasmic reticulum (ER)–mitochondria interactions and Ca2+ cross-talk E Zampese, C Fasolato, MJ Kipanyula, M Bortolozzi, T Pozzan, P Pizzo Proceedings of the National Academy of Sciences 108 (7), 2777-2782, 2011 | 304 | 2011 |
Calcium and Parkinson's disease DJ Surmeier, PT Schumacker, JD Guzman, E Ilijic, B Yang, E Zampese Biochemical and biophysical research communications 483 (4), 1013-1019, 2017 | 216 | 2017 |
Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain SM Graves, Z Xie, KA Stout, E Zampese, LF Burbulla, JC Shih, ... Nature neuroscience 23 (1), 15-20, 2020 | 129 | 2020 |
Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2 MJ Kipanyula, L Contreras, E Zampese, C Lazzari, AKC Wong, P Pizzo, ... Aging cell 11 (5), 885-893, 2012 | 110 | 2012 |
Presenilin‐2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake L Brunello, E Zampese, C Florean, T Pozzan, P Pizzo, C Fasolato Journal of cellular and molecular medicine 13 (9b), 3358-3369, 2009 | 102 | 2009 |
Intracellular organelles in the saga of Ca2+ homeostasis: different molecules for different purposes? E Zampese, P Pizzo Cellular and Molecular Life Sciences 69, 1077-1104, 2012 | 68 | 2012 |
α-Synuclein-dependent calcium entry underlies differential sensitivity of cultured SN and VTA dopaminergic neurons to a parkinsonian neurotoxin OJ Lieberman, SJ Choi, E Kanter, A Saverchenko, MD Frier, GM Fiore, ... Eneuro 4 (6), 2017 | 66 | 2017 |
Calcium, bioenergetics, and Parkinson’s disease E Zampese, DJ Surmeier Cells 9 (9), 2045, 2020 | 61 | 2020 |
Selective neuronal vulnerability in Parkinson's disease P Gonzalez-Rodriguez, E Zampese, DJ Surmeier Progress in brain research 252, 61-89, 2020 | 57 | 2020 |
Presenilin-2 modulation of ER-mitochondria interactions: FAD mutations, mechanisms and pathological consequences E Zampese, C Fasolato, T Pozzan, P Pizzo Communicative & integrative biology 4 (3), 357-360, 2011 | 44 | 2011 |
Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons E Zampese, DL Wokosin, P Gonzalez-Rodriguez, JN Guzman, T Tkatch, ... Science Advances 8 (39), eabp8701, 2022 | 35 | 2022 |
High content analysis of γ-secretase activity reveals variable dominance of presenilin mutations linked to familial Alzheimer's disease C Florean, E Zampese, M Zanese, L Brunello, F Ichas, F De Giorgi, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (8), 1551-1560, 2008 | 27 | 2008 |
Transient Activation of GABAB Receptors Suppresses SK Channel Currents in Substantia Nigra Pars Compacta Dopaminergic Neurons CM Estep, DJ Galtieri, E Zampese, JA Goldberg, L Brichta, P Greengard, ... PLoS One 11 (12), e0169044, 2016 | 17 | 2016 |
Endoplasmic reticulum-mitochondria connections, calcium cross-talk and cell fate: a closer inspection R Filadi, E Zampese, T Pozzan, P Pizzo, C Fasolato Endoplasmic Reticulum Stress in Health and Disease, 75-106, 2012 | 7 | 2012 |
Methamphetamine‐induced mitochondrial oxidant stress mediated by monoamine oxidase metabolism of dopamine SM Graves, Z Xie, E Zampese, KA Stout, RA Tai, SE Schwarzschild, ... The FASEB Journal 31, 987.3-987.3, 2017 | 6 | 2017 |
Ca2+ dysregulation mediated by presenilins in Familial Alzheimer’s Disease: Causing or modulating factor? E Zampese, L Brunello, C Fasolato, P Pizzo Current Trends in Neurology 3, 1-14, 2009 | 6 | 2009 |
Alpha-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinsons disease FF Geibl, MT Henrich, Z Xie, E Zampese, T Tkatch, DL Wokosin, E Nasiri, ... bioRxiv, 2023.12. 11.571045, 2023 | 5 | 2023 |