| Strategies for MMP inhibition in cancer: innovations for the post-trial era CM Overall, C López-Otín Nature Reviews Cancer 2 (9), 657-672, 2002 | 1708 | 2002 |
| Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy CM Overall, O Kleifeld Nature Reviews Cancer 6 (3), 227-239, 2006 | 1423 | 2006 |
| Human and mouse proteases: a comparative genomic approach XS Puente, LM Sánchez, CM Overall, C López-Otín Nature Reviews Genetics 4 (7), 544-558, 2003 | 1267 | 2003 |
| Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion K Wolf, YI Wu, Y Liu, J Geiger, E Tam, C Overall, MS Stack, P Friedl Nature cell biology 9 (8), 893-904, 2007 | 1224 | 2007 |
| Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3 GA McQuibban, JH Gong, EM Tam, CAG McCulloch, I Clark-Lewis, ... Science 289 (5482), 1202-1206, 2000 | 973 | 2000 |
| Protease degradomics: a new challenge for proteomics C López-Otín, CM Overall Nature reviews Molecular cell biology 3 (7), 509-519, 2002 | 954 | 2002 |
| Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-β CM Overall, JL Wrana, J Sodek Journal of Biological Chemistry 264 (3), 1860-1869, 1989 | 844 | 1989 |
| Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1 GA McQuibban, GS Butler, JH Gong, L Bendall, C Power, I Clark-Lewis, ... Journal of Biological Chemistry 276 (47), 43503-43508, 2001 | 790 | 2001 |
| Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 776 | 2011 |
| Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo GA McQuibban, JH Gong, JP Wong, JL Wallace, I Clark-Lewis, ... Blood, The Journal of the American Society of Hematology 100 (4), 1160-1167, 2002 | 768 | 2002 |
| Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics D Rodríguez, CJ Morrison, CM Overall Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (1), 39-54, 2010 | 706 | 2010 |
| Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites CM Overall Molecular biotechnology 22, 51-86, 2002 | 662 | 2002 |
| Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with … CM Overall, JL Wrana, J Sodek Journal of Biological Chemistry 266 (21), 14064-14071, 1991 | 615 | 1991 |
| Loss of collagenase-2 confers increased skin tumor susceptibility to male mice M Balbín, A Fueyo, AM Tester, AM Pendás, AS Pitiot, A Astudillo, ... Nature genetics 35 (3), 252-257, 2003 | 596 | 2003 |
| Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells R Khokha, P Waterhouse, S Yagel, PK Lala, CM Overall, G Norton, ... Science 243 (4893), 947-950, 1989 | 587 | 1989 |
| Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products O Kleifeld, A Doucet, U auf dem Keller, A Prudova, O Schilling, ... Nature biotechnology 28 (3), 281-288, 2010 | 566 | 2010 |
| Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: a comparison of sites in edentulous and partially edentulous patients P Apse, RP Ellen, CM Overall, GA Zarb Journal of periodontal research 24 (2), 96-105, 1989 | 524 | 1989 |
| Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites O Schilling, CM Overall Nature biotechnology 26 (6), 685-694, 2008 | 444 | 2008 |
| Towards third generation matrix metalloproteinase inhibitors for cancer therapy CM Overall, O Kleifeld British journal of cancer 94 (7), 941-946, 2006 | 422 | 2006 |
| Proteolytic host cell enzymes in gingival crevice fluid. VJ Uitto, CM Overall, C McCulloch Periodontology 2000 31 (1), 2003 | 413 | 2003 |
Georgina S. ButlerResearch Associate, Center for Blood Research, University of British Columbia, Canada.在 ubc.ca 的电子邮件经过验证
