MUC2 mucin and butyrate contribute to the synthesis of the antimicrobial peptide cathelicidin in response to Entamoeba histolytica-and dextran sodium sulfate-induced colitis ER Cobo, V Kissoon-Singh, F Moreau, R Holani, K Chadee Infection and immunity 85 (3), 10.1128/iai. 00905-16, 2017 | 82 | 2017 |
Proline-arginine rich (PR-39) cathelicidin: structure, expression and functional implication in intestinal health R Holani, C Shah, Q Haji, GD Inglis, RRE Uwiera, ER Cobo Comparative immunology, microbiology and infectious diseases 49, 95-101, 2016 | 38 | 2016 |
Human cathelicidin improves colonic epithelial defenses against Salmonella typhimurium by modulating bacterial invasion, TLR4 and pro-inflammatory cytokines M Marin, R Holani, GAD Blyth, D Drouin, A Odeón, ER Cobo Cell and tissue research 376, 433-442, 2019 | 33 | 2019 |
Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production R Holani, A Babbar, GAD Blyth, F Lopes, H Jijon, DM McKay, ... Gut Microbes 12 (1), 1785802, 2020 | 29 | 2020 |
Cathelicidin modulates synthesis of Toll-like receptors (TLRs) 4 and 9 in colonic epithelium M Marin, R Holani, CB Shah, A Odeón, ER Cobo Molecular immunology 91, 249-258, 2017 | 26 | 2017 |
Synthetic cathelicidin LL-37 reduces Mycobacterium avium subsp. paratuberculosis internalization and pro-inflammatory cytokines in macrophages KM Cirone, P Lahiri, R Holani, YL Tan, R Arrazuria, J De Buck, ... Cell and tissue research 379, 207-217, 2020 | 20 | 2020 |
Characteristic pro-inflammatory cytokines and host defence cathelicidin peptide produced by human monocyte-derived macrophages infected with Neospora caninum E Boucher, M Marin, R Holani, M Young-Speirs, DM Moore, ER Cobo Parasitology 145 (7), 871-884, 2018 | 19 | 2018 |
Entamoeba histolytica alters ileal Paneth cell functions in intact and Muc2 mucin deficiency ER Cobo, R Holani, F Moreau, K Nakamura, T Ayabe, JR Mastroianni, ... Infection and immunity 86 (7), 10.1128/iai. 00208-18, 2018 | 15 | 2018 |
Multiple micronutrient deficiencies in early life cause multi-kingdom alterations in the gut microbiome and intrinsic antibiotic resistance genes in mice PT Littlejohn, A Metcalfe-Roach, E Cardenas Poire, R Holani, ... Nature Microbiology 8 (12), 2392-2405, 2023 | 6 | 2023 |
Multiple micronutrient deficiencies alter energy metabolism in host and gut microbiome in an early-life murine model PT Littlejohn, H Bar-Yoseph, K Edwards, H Li, CY Ramirez-Contreras, ... Frontiers in Nutrition 10, 1151670, 2023 | 6 | 2023 |
Cathelicidins induce toll-interacting protein synthesis to prevent apoptosis in colonic epithelium R Holani, C Rathnayaka, GAD Blyth, A Babbar, P Lahiri, D Young, ... Journal of Innate Immunity 15 (1), 204-221, 2023 | 4 | 2023 |
Host defense peptides as innate immunomodulators in the pathogenesis of colitis R Holani, MS Marin, JP Kastelic, ER Cobo Antimicrobial Peptides in Gastrointestinal Diseases, 133-164, 2018 | 4 | 2018 |
Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins R Roca-Pinilla, R Holani, A López-Cano, C Saubi, R Baltà-Foix, ER Cobo, ... Scientific Reports 11 (1), 23798, 2021 | 3 | 2021 |
Bi-phase Extraction of Partially Purified Solanum tuberosum, Colocasia esculenta, Punica granatum and Phaseolus vulgaris Alkaline Phospahtases K Rani, R Holani, J Dharmwal Journal of Bio-innovation 1 (3), 70-76, 2012 | 3 | 2012 |
A murine model of maternal micronutrient deficiencies and gut inflammatory host-microbe interactions in the offspring R Holani, PT Littlejohn, K Edwards, C Petersen, KM Moon, RG Stacey, ... Cellular and Molecular Gastroenterology and Hepatology 17 (5), 827-852, 2024 | 2 | 2024 |
Cathelicidin Enhances the LPS‐Inducing Synthesis of Toll‐like Receptors 4 in the Colonic Epithelium M Marin, R Holani, C Shah, Q Haji, A Odeón, E Cobo The FASEB Journal 30, 517.2-517.2, 2016 | 2 | 2016 |
Secretory IgA in breast milk protects against asthma through modulation of the gut microbiota K Donald, A Serapio-Palacios, Z Gerbec, T Bozorgmehr, R Holani, ... Cell Reports 43 (10), 2024 | 1 | 2024 |
The effect of nutrient deprivation on early life small intestinal mucosal microbiome and host proteome H Bar-Yoseph, Z Krekhno, M Cirstea, R Holani, KM Moon, LJ Foster, ... The Journal of Nutrition 154 (2), 412-423, 2024 | 1 | 2024 |
Immunomodulatory Role of Cathelicidin at Colonic Epithelium R Holani Veterinary Medicine, 2020 | 1 | 2020 |
Bile acid–induced metabolic changes in the colon promote Enterobacteriaceae expansion and associate with dysbiosis in Crohn’s disease R Holani, H Bar-Yoseph, Z Krekhno, A Serapio-Palacios, KM Moon, ... Science Signaling 17 (867), eadl1786, 2024 | | 2024 |