Replication fork stability confers chemoresistance in BRCA-deficient cells A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ... Nature 535 (7612), 382-387, 2016 | 874 | 2016 |
p38 Mitogen-Activated Protein Kinase- and HuR-Dependent Stabilization of p21Cip1 mRNA Mediates the G1/S Checkpoint V Lafarga, A Cuadrado, I Lopez de Silanes, R Bengoechea, ... Molecular and cellular biology 29 (16), 4341-4351, 2009 | 302 | 2009 |
The complex G protein‐coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets P Penela, C Murga, C Ribas, V Lafarga, F Mayor Jr British journal of pharmacology 160 (4), 821-832, 2010 | 264 | 2010 |
A genome-wide CRISPR screen identifies CDC25A as a determinant of sensitivity to ATR inhibitors S Ruiz, C Mayor-Ruiz, V Lafarga, M Murga, M Vega-Sendino, S Ortega, ... Molecular cell 62 (2), 307-313, 2016 | 205 | 2016 |
A novel GRK2/HDAC6 interaction modulates cell spreading and motility V Lafarga, I Aymerich, O Tapia, F Mayor Jr, P Penela The EMBO journal 31 (4), 856-869, 2012 | 134 | 2012 |
A new p38 MAP kinase‐regulated transcriptional coactivator that stimulates p53‐dependent apoptosis A Cuadrado, V Lafarga, PCF Cheung, I Dolado, S Llanos, P Cohen, ... The EMBO journal 26 (8), 2115-2126, 2007 | 114 | 2007 |
Essential role of p18Hamlet/SRCAP‐mediated histone H2A. Z chromatin incorporation in muscle differentiation A Cuadrado, N Corrado, E Perdiguero, V Lafarga, P Muñoz‐Canoves, ... The EMBO journal 29 (12), 2014-2025, 2010 | 84 | 2010 |
Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML I Morgado-Palacin, A Day, M Murga, V Lafarga, ME Anton, A Tubbs, ... Science signaling 9 (445), ra91-ra91, 2016 | 75 | 2016 |
G protein-coupled receptor kinase 2 (GRK2) promotes breast tumorigenesis through a HDAC6-Pin1 axis L Nogués, C Reglero, V Rivas, A Salcedo, V Lafarga, M Neves, P Ramos, ... EBioMedicine 13, 132-145, 2016 | 72 | 2016 |
Efficacy of ATR inhibitors as single agents in Ewing sarcoma M Nieto-Soler, I Morgado-Palacin, V Lafarga, E Lecona, M Murga, ... Oncotarget 7 (37), 58759, 2016 | 72 | 2016 |
PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection C Morales, M Ruiz-Torres, S Rodríguez-Acebes, V Lafarga, ... Journal of Biological Chemistry 295 (1), 146-157, 2020 | 53 | 2020 |
Purkinje cell degeneration in pcd mice reveals large scale chromatin reorganization and gene silencing linked to defective DNA repair FC Baltanás, I Casafont, V Lafarga, E Weruaga, JR Alonso, MT Berciano, ... Journal of Biological Chemistry 286 (32), 28287-28302, 2011 | 52 | 2011 |
Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland E García-Zaragoza, R Pérez-Tavarez, A Ballester, V Lafarga, ... Developmental biology 372 (1), 28-44, 2012 | 51 | 2012 |
Effect of ionizing radiation in sensory ganglion neurons: organization and dynamics of nuclear compartments of DNA damage/repair and their relationship with transcription and … I Casafont, A Palanca, V Lafarga, MT Berciano, M Lafarga Acta neuropathologica 122, 481-493, 2011 | 47 | 2011 |
The SMN Tudor SIM-like domain is key to SmD1 and coilin interactions and to Cajal body biogenesis O Tapia, V Lafarga, R Bengoechea, A Palanca, M Lafarga, MT Berciano Journal of cell science 127 (5), 939-946, 2014 | 33 | 2014 |
Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility P Penela, V Lafarga, O Tapia, V Rivas, L Nogués, E Lucas, ... Science Signaling 5 (224), pt3-pt3, 2012 | 32 | 2012 |
Targeting the nucleolus as a therapeutic strategy in human disease A Corman, O Sirozh, V Lafarga, O Fernandez-Capetillo Trends in Biochemical Sciences 48 (3), 274-287, 2023 | 31 | 2023 |
USP7 limits CDK1 activity throughout the cell cycle A Galarreta, P Valledor, P Ubieto‐Capella, V Lafarga, E Zarzuela, ... The EMBO Journal 40 (11), e99692, 2021 | 31 | 2021 |
The interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility V Lafarga, F Mayor, Jr, P Penela Cell adhesion & migration 6 (6), 495-501, 2012 | 27 | 2012 |
Widespread displacement of DNA‐and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides V Lafarga, O Sirozh, I Díaz‐López, A Galarreta, M Hisaoka, E Zarzuela, ... The EMBO Journal 40 (13), e103311, 2021 | 26 | 2021 |