Reducing endogenous tau ameliorates amyloid ß-induced deficits in an Alzheimer's disease mouse model ED Roberson, K Scearce-Levie, JJ Palop, F Yan, IH Cheng, T Wu, ... Science 316 (5825), 750-754, 2007 | 2308 | 2007 |
The effect of large-scale anti-contagion policies on the COVID-19 pandemic S Hsiang, D Allen, S Annan-Phan, K Bell, I Bolliger, T Chong, ... Nature 584 (7820), 262-267, 2020 | 1614 | 2020 |
Amyloid-β/Fyn–induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease ED Roberson, B Halabisky, JW Yoo, J Yao, J Chin, F Yan, T Wu, P Hamto, ... Journal of Neuroscience 31 (2), 700-711, 2011 | 742 | 2011 |
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration D Zwilling, SY Huang, KV Sathyasaikumar, FM Notarangelo, P Guidetti, ... Cell 145 (6), 863-874, 2011 | 517 | 2011 |
Changes in the synaptic proteome in tauopathy and rescue of tau-induced synapse loss by C1q antibodies B Dejanovic, MA Huntley, A De Mazière, WJ Meilandt, T Wu, K Srinivasan, ... Neuron 100 (6), 1322-1336. e7, 2018 | 366 | 2018 |
Complement C3 is activated in human AD brain and is required for neurodegeneration in mouse models of amyloidosis and tauopathy T Wu, B Dejanovic, VD Gandham, A Gogineni, R Edmonds, S Schauer, ... Cell reports 28 (8), 2111-2123. e6, 2019 | 313 | 2019 |
Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Aβ oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice WJ Meilandt, M Cisse, K Ho, T Wu, LA Esposito, K Scearce-Levie, ... Journal of Neuroscience 29 (7), 1977-1986, 2009 | 186 | 2009 |
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimer … WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ... Journal of Neuroscience 40 (9), 1956-1974, 2020 | 129 | 2020 |
Reversal-specific learning impairments after a binge regimen of methamphetamine in rats: possible involvement of striatal dopamine A Izquierdo, AM Belcher, L Scott, VA Cazares, J Chen, SJ O'dell, ... Neuropsychopharmacology 35 (2), 505-514, 2010 | 119 | 2010 |
First 12 patients with coronavirus disease 2019 (COVID-19) in the United States COVID-19 Investigation Team, SA Kujawski, KK Wong, JP Collins, ... MedRxiv, 2020.03. 09.20032896, 2020 | 110 | 2020 |
Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease WJ Meilandt, GQ Yu, J Chin, ED Roberson, JJ Palop, T Wu, ... Journal of Neuroscience 28 (19), 5007-5017, 2008 | 107 | 2008 |
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models B Dejanovic, T Wu, MC Tsai, D Graykowski, VD Gandham, CM Rose, ... Nature aging 2 (9), 837-850, 2022 | 71 | 2022 |
Cognitive deficits, changes in synaptic function, and brain pathology in a mouse model of normal aging M Weber, T Wu, JE Hanson, NM Alam, H Solanoy, H Ngu, BE Lauffer, ... ENeuro 2 (5), 2015 | 67 | 2015 |
Inflammatory and noninflammatory itch: implications in pathophysiology-directed treatments LS Wong, T Wu, CH Lee International journal of molecular sciences 18 (7), 1485, 2017 | 59 | 2017 |
Role of membrane-tension gated Ca2+ flux in cell mechanosensation L He, J Tao, D Maity, F Si, Y Wu, T Wu, V Prasath, D Wirtz, SX Sun Journal of cell science 131 (4), jcs208470, 2018 | 57 | 2018 |
GluN2B antagonism affects interneurons and leads to immediate and persistent changes in synaptic plasticity, oscillations, and behavior JE Hanson, M Weber, WJ Meilandt, T Wu, T Luu, L Deng, M Shamloo, ... Neuropsychopharmacology 38 (7), 1221-1233, 2013 | 56 | 2013 |
A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in … DY Kallop, WJ Meilandt, A Gogineni, C Easley-Neal, T Wu, AM Jubb, ... Journal of Neuroscience 34 (19), 6425-6437, 2014 | 45 | 2014 |
Functional tunability from a distance: Rheostat positions influence allosteric coupling between two distant binding sites T Wu, L Swint-Kruse, AW Fenton Scientific reports 9 (1), 16957, 2019 | 18 | 2019 |
BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats M Weber, T Wu, WJ Meilandt, SL Dominguez, HO Solanoy, JA Maloney, ... Scientific Reports 7 (1), 44249, 2017 | 18 | 2017 |
Publisher Correction: The effect of large-scale anti-contagion policies on the COVID-19 pandemic S Hsiang, D Allen, S Annan-Phan, K Bell, I Bolliger, T Chong, ... Nature 585 (7824), E7, 2020 | 16 | 2020 |