Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens F Wegmann, KH Gartlan, AM Harandi, SA Brinckmann, M Coccia, ... Nature biotechnology 30 (9), 883-888, 2012 | 222 | 2012 |
Nanomaterials for T-cell cancer immunotherapy N Gong, NC Sheppard, MM Billingsley, CH June, MJ Mitchell Nature Nanotechnology 16 (1), 25-36, 2021 | 208 | 2021 |
Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity L Kong, NC Sheppard, GBE Stewart-Jones, CL Robson, H Chen, X Xu, ... Journal of molecular biology 403 (1), 131-147, 2010 | 119 | 2010 |
HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates RB Jones, KE Garrison, S Mujib, V Mihajlovic, N Aidarus, DV Hunter, ... The Journal of clinical investigation 122 (12), 2012 | 102 | 2012 |
Genetic engineering of T cells for immunotherapy GI Ellis, NC Sheppard, JL Riley Nature Reviews Genetics 22 (7), 427-447, 2021 | 90 | 2021 |
Orthogonal design of experiments for optimization of lipid nanoparticles for mRNA engineering of CAR T cells MM Billingsley, AG Hamilton, D Mai, SK Patel, KL Swingle, NC Sheppard, ... Nano letters 22 (1), 533-542, 2021 | 77 | 2021 |
EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium PA Bart, R Goodall, T Barber, A Harari, A Guimaraes-Walker, M Khonkarly, ... Vaccine 26 (25), 3153-3161, 2008 | 77 | 2008 |
Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens NC Sheppard, SA Brinckmann, KH Gartlan, M Puthia, C Svanborg, ... International immunology 26 (10), 531-538, 2014 | 72 | 2014 |
Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates BE Verstrepen, AD Bins, CS Rollier, P Mooij, G Koopman, NC Sheppard, ... Vaccine 26 (26), 3346-3351, 2008 | 72 | 2008 |
The TRIM5α genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge MR Reynolds, JB Sacha, AM Weiler, GJ Borchardt, CE Glidden, ... Journal of virology 85 (18), 9637-9640, 2011 | 67 | 2011 |
Vaccination with cancer-and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic JB Sacha, IJ Kim, L Chen, JH Ullah, DA Goodwin, HA Simmons, ... The Journal of Immunology 189 (3), 1467-1479, 2012 | 62 | 2012 |
Comparison of human and rhesus macaque T-cell responses elicited by boosting with NYVAC encoding human immunodeficiency virus type 1 clade C immunogens P Mooij, SS Balla-Jhagjhoorsingh, N Beenhakker, P van Haaften, I Baak, ... Journal of virology 83 (11), 5881-5889, 2009 | 40 | 2009 |
Combined disruption of T cell inflammatory regulators Regnase-1 and Roquin-1 enhances antitumor activity of engineered human T cells D Mai, O Johnson, J Reff, TJ Fan, J Scholler, NC Sheppard, CH June Proceedings of the National Academy of Sciences 120 (12), e2218632120, 2023 | 28 | 2023 |
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering AG Hamilton, KL Swingle, RA Joseph, D Mai, N Gong, MM Billingsley, ... Advanced Healthcare Materials 12 (30), 2301515, 2023 | 16 | 2023 |
Human endogenous retrovirus K (HML-2) Gag-and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening RB Jones, VM John, DV Hunter, E Martin, S Mujib, V Mihajlovic, ... Clinical and Vaccine Immunology 19 (2), 288-292, 2012 | 15 | 2012 |
Adjuvant Q Sattentau, N Sheppard US Patent App. 12/293,380, 2009 | 15 | 2009 |
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells AR Haas, RJ Golden, LA Litzky, B Engels, L Zhao, F Xu, JA Taraszka, ... Molecular Therapy 31 (8), 2309-2325, 2023 | 14 | 2023 |
A functional human IgM response to HIV-1 Env after immunization with NYVAC HIV C NC Sheppard, AC Bates, QJ Sattentau Aids 21 (4), 524-527, 2007 | 14 | 2007 |
In vivo screen of genetically conserved Streptococcus pneumoniae proteins for protective immunogenicity RJ Anderson, S Guru, R Weeratna, S Makinen, DJ Falconer, ... Vaccine 34 (50), 6292-6300, 2016 | 11 | 2016 |
Vaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replication NC Sheppard, RB Jones, BJ Burwitz, FA Nimityongskul, LP Newman, ... PLoS One 9 (3), e92012, 2014 | 11 | 2014 |