Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA JCC Lorenzi*, YZ Cohen*, LB Cohn, EF Kreider, JP Barton, GH Learn, ... Proceedings of the National Academy of Sciences 113 (49), E7908–E7916, 2016 | 194 | 2016 |
The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing JK Mann*, JP Barton*, AL Ferguson*, S Omarjee, BD Walker, ... PLoS Computational Biology 10 (8), e1003776, 2014 | 161 | 2014 |
Deconstruction of the Ras switching cycle through saturation mutagenesis P Bandaru, NH Shah, M Bhattacharyya, JP Barton, Y Kondo, JC Cofsky, ... Elife 6, e27810, 2017 | 118 | 2017 |
Fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies RHY Louie*, KJ Kaczorowski*, JP Barton, AK Chakraborty, MR McKay Proceedings of the National Academy of Sciences, 201717765, 2018 | 111 | 2018 |
Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable JP Barton, N Goonetilleke, TC Butler, BD Walker, AJ McMichael, ... Nature Communications 7, 11660, 2016 | 108 | 2016 |
Relationship between latent and rebound viruses in a clinical trial of anti–HIV-1 antibody 3BNC117 YZ Cohen, JCC Lorenzi, L Krassnig, JP Barton, L Burke, J Pai, CL Lu, ... Journal of Experimental Medicine 215 (9), 2311-2324, 2018 | 105 | 2018 |
ACE: adaptive cluster expansion for maximum entropy graphical model inference JP Barton†, E De Leonardis, A Coucke, S Cocco† Bioinformatics 32 (20), 3089-3097, 2016 | 104 | 2016 |
Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies V Ovchinnikov*, JE Louveau*, JP Barton*, M Karplus, AK Chakraborty eLife 7, e33038, 2018 | 95 | 2018 |
Dietary supplements and nutraceuticals under investigation for COVID-19 prevention and treatment R Lordan, HM Rando, CS Greene Msystems 6 (3), 10.1128/msystems. 00122-21, 2021 | 93 | 2021 |
Spin models inferred from patient-derived viral sequence data faithfully describe HIV fitness landscapes K Shekhar, CF Ruberman, AL Ferguson, JP Barton, M Kardar, ... Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 88 (6 …, 2013 | 89 | 2013 |
Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruption CL Lu, JA Pai, L Nogueira, P Mendoza, H Gruell, TY Oliveira, J Barton, ... Proceedings of the National Academy of Sciences 115 (48), E11341-E11348, 2018 | 76 | 2018 |
Characterization of intact proviruses in blood and lymph node from HIV-infected individuals undergoing analytical treatment interruption LK Vibholm, JCC Lorenzi, JA Pai, YZ Cohen, TY Oliveira, JP Barton, ... Journal of Virology 93 (8), 2019 | 65 | 2019 |
Ising models for neural activity inferred via selective cluster expansion: structural and coding properties J Barton, S Cocco Journal of Statistical Mechanics: Theory and Experiment 2013 (03), P03002, 2013 | 47 | 2013 |
Scaling laws describe memories of host–pathogen riposte in the HIV population JP Barton, M Kardar, AK Chakraborty Proceedings of the National Academy of Sciences 112 (7), 1965-1970, 2015 | 37 | 2015 |
Large pseudocounts and L2-norm penalties are necessary for the mean-field inference of Ising and Potts models JP Barton, S Cocco, E De Leonardis, R Monasson Physical Review E 90 (1), 012132, 2014 | 36 | 2014 |
Pathogenesis, symptomatology, and transmission of SARS-CoV-2 through analysis of viral genomics and structure HM Rando, AL MacLean, AJ Lee, R Lordan, S Ray, V Bansal, AN Skelly, ... MSystems 6 (5), 10.1128/msystems. 00095-21, 2021 | 35* | 2021 |
Deconvolving mutational patterns of poliovirus outbreaks reveals its intrinsic fitness landscape AA Quadeer, JP Barton, AK Chakraborty, MR McKay Nature communications 11 (1), 377, 2020 | 33 | 2020 |
Identification of drug resistance mutations in HIV from constraints on natural evolution TC Butler*, JP Barton*, M Kardar, AK Chakraborty Physical Review E 93 (2), 022412, 2016 | 33 | 2016 |
MPL resolves genetic linkage in fitness inference from complex evolutionary histories MS Sohail, RHY Louie, MR McKay, JP Barton Nature Biotechnology 39 (4), 472-479, 2021 | 28 | 2021 |
The energy costs of insulators in biochemical networks JP Barton, ED Sontag Biophysical Journal 104 (6), 1380-1390, 2013 | 28 | 2013 |