Most LQT2 mutations reduce Kv11. 1 (hERG) current by a class 2 (trafficking-deficient) mechanism CL Anderson, BP Delisle, BD Anson, JA Kilby, ML Will, DJ Tester, Q Gong, ... Circulation 113 (3), 365-373, 2006 | 500 | 2006 |
Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine S Rajamani, LL Eckhardt, CR Valdivia, CA Klemens, BM Gillman, ... British journal of pharmacology 149 (5), 481-489, 2006 | 237 | 2006 |
Role of glycosylation in cell surface expression and stability of HERG potassium channels Q Gong, CL Anderson, CT January, Z Zhou American Journal of Physiology-Heart and Circulatory Physiology 283 (1), H77-H84, 2002 | 194 | 2002 |
Pharmacological Rescue of Human K+ Channel Long-QT2 Mutations: Human Ether-a-Go-Go-Related Gene Rescue Without Block S Rajamani, CL Anderson, BD Anson, CT January Circulation 105 (24), 2830-2835, 2002 | 176 | 2002 |
Large-scale mutational analysis of Kv11.1 reveals molecular insights into type 2 long QT syndrome CL Anderson, CE Kuzmicki, RR Childs, H CJ, D BP, J CT Nature Communications 5 (5535), 2014 | 175 | 2014 |
Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels BD Anson, MJ Ackerman, DJ Tester, ML Will, BP Delisle, CL Anderson, ... American Journal of Physiology-Heart and Circulatory Physiology 286 (6 …, 2004 | 149 | 2004 |
Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C BP Delisle, CL Anderson, RC Balijepalli, BD Anson, TJ Kamp, CT January Journal of Biological Chemistry 278 (37), 35749-35754, 2003 | 116 | 2003 |
Molecular pathogenesis of long QT syndrome type 2 J Smith, C Anderson, D Burgess, C Elayi, C January, B Delisle Journal of Arrhythmia, 2016 | 100 | 2016 |
Cell‐free complements in vivo expression of the E. coli membrane proteome DF Savage, CL Anderson, Y Robles‐Colmenares, ZE Newby, RM Stroud Protein Science 16 (5), 966-976, 2007 | 74 | 2007 |
Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits Q Gong, CL Anderson, CT January, Z Zhou American Journal of Physiology-Heart and Circulatory Physiology 287 (2 …, 2004 | 60 | 2004 |
Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and IKr S Rajamani, CL Anderson, CR Valdivia, LL Eckhardt, JD Foell, ... American Journal of Physiology-Heart and Circulatory Physiology 290 (3 …, 2006 | 56 | 2006 |
Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 KCNH2 (hERG) Mutations and Identifying New Patients M Ono, DE Burgess, EA Schroder, CS Elayi, CL Anderson, CT January, ... Biomolecules 10 (8), 1144, 2020 | 38 | 2020 |
Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic … JL Smith, AR Reloj, PS Nataraj, DC Bartos, EA Schroder, AJ Moss, ... American Journal of Physiology-Cell Physiology 305 (9), C919-C930, 2013 | 37 | 2013 |
HYDROLYTIC SELECTIVITY OF PATATIN (LIPID ACYL HYDROLASE) FROM POTATO (SOLANUM TUBEROSUM L.) TUBERS TOWARD VARIOUS LIPIDS C ANDERSON, P PINSIRODOM, KL PARKIN Journal of Food Biochemistry 26 (1), 63-74, 2002 | 31 | 2002 |
Intragenic suppression of trafficking-defective KCNH2 channels associated with long QT syndrome BP Delisle, JK Slind, JA Kilby, CL Anderson, BD Anson, RC Balijepalli, ... Molecular pharmacology 68 (1), 233-240, 2005 | 29 | 2005 |
Rescue of mutated cardiac ion channels in inherited arrhythmia syndromes SY Balijepalli, CL Anderson, EC Lin, CT January Journal of cardiovascular pharmacology 56 (2), 113-122, 2010 | 26 | 2010 |
Most myopathic lamin variants aggregate: A functional genomics approach for assessing variants of uncertain significance CL Anderson, ER Langer, TC Routes, SF McWilliams, I Bereslavskyy, ... NPJ Genomic Medicine 6 (1), 103, 2021 | 15 | 2021 |
Long QT Syndrome KCNH2 Variant Induces hERG1a/1b Subunit Imbalance in Patient-Specific Induced Pluripotent Stem Cell–Derived Cardiomyocytes L Feng, J Zhang, CH Lee, G Kim, F Liu, AJ Petersen, E Lim, CL Anderson, ... Circulation: Arrhythmia and Electrophysiology 14 (4), e009343, 2021 | 13 | 2021 |
How functional genomics can keep pace with VUS identification CL Anderson, S Munawar, L Reilly, TJ Kamp, CT January, BP Delisle, ... Frontiers in Cardiovascular Medicine 9, 900431, 2022 | 11 | 2022 |
Genetic basis for the origin of cardiac arrhythmias: implications for therapy M Mbai, S Rajamani, BP Delisle, BD Anson, C Anderson, JC Makielski, ... Current Cardiology Reports 4, 411-417, 2002 | 10 | 2002 |