A Transient Receptor Potential Ion Channel in Chlamydomonas Shares Key Features with Sensory Transduction-Associated TRP Channels in Mammals L Arias-Darraz, D Cabezas, CK Colenso, M Alegría-Arcos, ... The Plant Cell 27 (1), 177-188, 2015 | 59 | 2015 |
A physicochemical and conformational study of co-solvent effect on the molecular interactions between similarly charged protein surfactant (BSA-SDBS) system V Sharma, O Yañez, M Alegría-Arcos, A Kumar, RC Thakur, ... The Journal of Chemical Thermodynamics 142, 106022, 2020 | 38 | 2020 |
Participation of the Salmonella OmpD Porin in the Infection of RAW264.7 Macrophages and BALB/c Mice CPS Francisco Ipinza , Bernardo Collao , Debbie Monsalva, Victor H ... PLoS ONE 9 (10), e111062, 2014 | 38 | 2014 |
Penicillium purpurogenum produces two GH family 43 enzymes with β-xylosidase activity, one monofunctional and the other bifunctional: Biochemical and structural analyses … MC Ravanal, M Alegría-Arcos, FD Gonzalez-Nilo, J Eyzaguirre Archives of Biochemistry and Biophysics 540 (1-2), 117-124, 2013 | 31 | 2013 |
Analysis of the Zonula occludens Toxin Found in the Genome of the Chilean Non-toxigenic Vibrio parahaemolyticus Strain PMC53.7 D Pérez-Reytor, A Pavón, C Lopez-Joven, S Ramírez-Araya, ... Frontiers in cellular and infection microbiology 10, 482, 2020 | 21 | 2020 |
Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors L Gallego-Yerga, R Ochoa, I Lans, C Peña-Varas, M Alegría-Arcos, ... Computational and Structural Biotechnology Journal 19, 4360-4372, 2021 | 18 | 2021 |
PSC-db: a structured and searchable 3D-database for plant secondary compounds A Valdés-Jiménez, C Peña-Varas, P Borrego-Muñoz, L Arrue, ... Molecules 26 (4), 1124, 2021 | 16 | 2021 |
IR and NMR spectroscopic correlation of enterobactin by DFT M Moreno, A Zacarias, A Porzel, L Velasquez, G Gonzalez, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 198, 264-277, 2018 | 14 | 2018 |
Network pharmacology reveals multitarget mechanism of action of drugs to be repurposed for COVID-19 M Alegría-Arcos, T Barbosa, F Sepúlveda, G Combariza, J González, ... Frontiers in Pharmacology, 2022 | 12 | 2022 |
Unnexins: Homologs of innexin proteins in Trypanosomatidae parasites J Güiza, A García, J Arriagada, C Gutiérrez, J González, ... Journal of Cellular Physiology 237 (2), 1547-1560, 2022 | 5 | 2022 |
Calcium-alginate-chitosan nanoparticle as a potential solution for pesticide removal, a computational approach O Yáñez, M Alegría-Arcos, R Suardiaz, L Morales-Quintana, RI Castro, ... Polymers 15 (14), 3020, 2023 | 4 | 2023 |
Method and system for characterization of metabolism-associated conditions, including diagnostics and therapies, based on bioinformatics approach Z Apte, J Richman, D Almonacid, I Pedroso, V Dumas, V Marquez, I Araya, ... US Patent App. 16/755,233, 2021 | 3 | 2021 |
Unveiling Novel Urease Inhibitors for Helicobacter pylori: A Multi-Methodological Approach from Virtual Screening and ADME to Molecular Dynamics Simulations P Valenzuela-Hormazabal, RV Sepúlveda, M Alegría-Arcos, ... International journal of molecular sciences 25 (4), 1968, 2024 | 2 | 2024 |
Rieske-type oxygenase/reductase targeted drugs for diagnostic and treatment of diseases Z Apte, J Richman, D Almonacid, V Marquez, I Araya, M Alegria, ... US Patent App. 16/103,830, 2019 | 2 | 2019 |
IDH1 and IDH2 mutants identified in cancer lose inhibition by isocitrate because of a change in their binding sites JP Bascur, M Alegría-Arcos, I Araya-Durán, EI Juritz, FD González-Nilo, ... bioRxiv, 425025, 2018 | 2 | 2018 |
A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel CA Amaya-Rodriguez, K Carvajal-Zamorano, D Bustos, M Alegría-Arcos, ... Frontiers in Pharmacology 14, 1251061, 2024 | 1 | 2024 |
Open protocols for docking and MD-based scoring of peptide substrates R Ochoa, Á Santiago, M Alegría-Arcos Artificial Intelligence in the Life Sciences 2, 100044, 2022 | 1 | 2022 |
From Proteome to Potential Drugs: Integration of Subtractive Proteomics and Ensemble Docking for Drug Repurposing against Pseudomonas aeruginosa RND … G Urra, E Valdés-Muñoz, R Suardiaz, EW Hernández-Rodríguez, ... International Journal of Molecular Sciences 25 (15), 8027, 2024 | | 2024 |
Prophages carrying Zot toxins on different Vibrio genomes: A comprehensive assessment using multilayer networks EF Soto, M Alegría, F Sepúlveda, K García, G Higuera, D Castillo, ... Environmental Microbiology 26 (5), e16654, 2024 | | 2024 |
Therapeutic and diagnostics compositions targeting toll-like receptors and methods thereof Z Apte, J Richman, D Almonacid, M Alegria, V Marquez, E Morales, ... US Patent 11,931,400, 2024 | | 2024 |