Senescence in post-mitotic cells: a driver of aging? T von Zglinicki, T Wan, S Miwa Antioxidants & redox signaling 34 (4), 308-323, 2021 | 150 | 2021 |
Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria S Miwa, R Czapiewski, T Wan, A Bell, KN Hill, T von Zglinicki, G Saretzki Aging (Albany NY) 8 (10), 2551, 2016 | 95 | 2016 |
Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagy T Wan, EJ Weir, M Johnson, VI Korolchuk, GC Saretzki Progress in neurobiology 199, 101953, 2021 | 49 | 2021 |
Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice E Fielder, T Wan, G Alimohammadiha, A Ishaq, E Low, BM Weigand, ... Elife 11, e75492, 2022 | 44 | 2022 |
iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors D Melguizo-Sanchis, Y Xu, D Taheem, M Yu, K Tilgner, T Barta, ... Cell death & disease 9 (2), 128, 2018 | 38 | 2018 |
Telomerase in brain: The new kid on the block and its role in neurodegenerative diseases G Saretzki, T Wan Biomedicines 9 (5), 490, 2021 | 28 | 2021 |
Dietary restriction mitigates age-related accumulation of DNA damage, but not all changes in mouse corneal epithelium D Hallam, T Wan, G Saretzki Experimental Gerontology 67, 72-79, 2015 | 6 | 2015 |
Characterisation of oxidative stress, DNA damage and inflammation in a cellular model of Parkinson’s disease A Khan, T Wan, C Hunter, P Schweizer, S Nagarathanam, J Morris, ... OBM Neurobiology 3 (3), 1-21, 2019 | 1 | 2019 |
Cell senescence is a cause of frailty T Wan, S Miwa, T von Zglinicki Cellular Senescence in Disease, 383-422, 2022 | | 2022 |
Telomerase Improves PD Symptoms and Pathology T Wan, EJ Weir, M Johnson, VI Korolchuk, GC Saretzki BP International, 2021 | | 2021 |