Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease R Balez, N Steiner, M Engel, SS Muñoz, JS Lum, Y Wu, D Wang, ... Scientific reports 6 (1), 31450, 2016 | 247 | 2016 |
Negativity towards negative results: a discussion of the disconnect between scientific worth and scientific culture N Matosin, E Frank, M Engel, JS Lum, KA Newell Disease models & mechanisms 7 (2), 171-173, 2014 | 241 | 2014 |
Molecular evidence of synaptic pathology in the CA1 region in schizophrenia N Matosin, F Fernandez-Enright, JS Lum, M Engel, JL Andrews, ... npj Schizophrenia 2 (1), 1-8, 2016 | 78 | 2016 |
Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research M Engel, D Do-Ha, S Sanz Munoz, L Ooi Cellular and Molecular Life Sciences, 2016 | 75 | 2016 |
Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway C Deng, B Pan, M Engel, XF Huang Psychopharmacology 226, 201-215, 2013 | 73 | 2013 |
Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway UA Bommer, V Iadevaia, J Chen, B Knoch, M Engel, CG Proud Cellular signalling 27 (8), 1557-1568, 2015 | 50 | 2015 |
Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin UA Bommer, KL Vine, P Puri, M Engel, L Belfiore, K Fildes, M Batterham, ... Cell Communication and Signaling 15, 1-15, 2017 | 49 | 2017 |
Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation N Matosin, F Fernandez-Enright, SJ Fung, JS Lum, M Engel, JL Andrews, ... Acta neuropathologica 130, 119-129, 2015 | 45 | 2015 |
Generation and analysis of 3D cell culture models for drug discovery L Belfiore, B Aghaei, AMK Law, JC Dobrowolski, LJ Raftery, AD Tjandra, ... European Journal of Pharmaceutical Sciences 163, 105876, 2021 | 42 | 2021 |
The ubiquitin proteasome system is a key regulator of pluripotent stem cell survival and motor neuron differentiation M Bax, J McKenna, D Do-Ha, CH Stevens, S Higginbottom, R Balez, ... Cells 8 (6), 581, 2019 | 41 | 2019 |
Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats I Babic, A Gorak, M Engel, D Sellers, P Else, AL Osborne, N Pai, ... Journal of Psychopharmacology 32 (5), 578-590, 2018 | 38 | 2018 |
A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer’s Disease and Frontotemporal … SS Muñoz, M Engel, R Balez, D Do-Ha, MC Cabral-da-Silva, ... Cells 9 (9), 2018, 2020 | 37 | 2020 |
Enabling high throughput drug discovery in 3D cell cultures through a novel bioprinting workflow M Engel, L Belfiore, B Aghaei, M Sutija SLAS technology 27 (1), 32-38, 2022 | 32 | 2022 |
A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability MS Jung, JN Skhinas, EY Du, MAK Tolentino, RH Utama, M Engel, ... Biomaterials Science 10 (20), 5876-5887, 2022 | 30 | 2022 |
If human brain organoids are the answer to understanding dementia, what are the questions? L Ooi, M Dottori, AL Cook, M Engel, V Gautam, A Grubman, D Hernández, ... The Neuroscientist 26 (5-6), 438-454, 2020 | 29 | 2020 |
Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia N Matosin, F Fernandez-Enright, JS Lum, JL Andrews, M Engel, ... Schizophrenia research 166 (1-3), 212-218, 2015 | 29 | 2015 |
Advanced Spheroid, Tumouroid and 3D Bioprinted In-Vitro Models of Adult and Paediatric Glioblastoma L Orcheston-Findlay, S Bax, R Utama, M Engel, D Govender, G O’Neill International Journal of Molecular Sciences 22 (6), 2962, 2021 | 22 | 2021 |
Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing … SS Muñoz, R Balez, T Berg, M Engel, M Bax, D Do-Ha, CH Stevens, ... Stem cell research 31, 227-230, 2018 | 18 | 2018 |
Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice M Engel, P Snikeris, A Jenner, T Karl, XF Huang, E Frank International Journal of Neuropsychopharmacology, 2014 | 18 | 2014 |
Novel dual‐action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine‐specific histone demethylase 1A inhibitor M Engel, YS Gee, D Cross, A Maccarone, B Heng, A Hulme, G Smith, ... Journal of neurochemistry 149 (4), 535-550, 2019 | 17 | 2019 |