| Allosteric communication networks in proteins revealed through pocket crosstalk analysis G La Sala, S Decherchi, M De Vivo, W Rocchia ACS central science 3 (9), 949-960, 2017 | 71 | 2017 |
| Discovery of a small molecule drug candidate for selective NKCC1 inhibition in brain disorders A Savardi, M Borgogno, R Narducci, G La Sala, JA Ortega, M Summa, ... Chem 6 (8), 2073-2096, 2020 | 58 | 2020 |
| Structure, thermodynamics, and kinetics of plinabulin binding to two tubulin isotypes G La Sala, N Olieric, A Sharma, F Viti, FAB Perez, L Huang, JR Tonra, ... Chem 5 (11), 2969-2986, 2019 | 41 | 2019 |
| Studies on the ATP binding site of Fyn kinase for the identification of new inhibitors and their evaluation as potential agents against tauopathies and tumors C Tintori, G La Sala, G Vignaroli, L Botta, AL Fallacara, F Falchi, M Radi, ... Journal of Medicinal Chemistry 58 (11), 4590-4609, 2015 | 41 | 2015 |
| HRD motif as the central hub of the signaling network for activation loop autophosphorylation in Abl kinase G La Sala, L Riccardi, R Gaspari, A Cavalli, O Hantschel, M De Vivo Journal of chemical theory and computation 12 (11), 5563-5574, 2016 | 27 | 2016 |
| Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms DP Duarte, AJ Lamontanara, G La Sala, S Jeong, YK Sohn, A Panjkovich, ... Nature communications 11 (1), 2319, 2020 | 26 | 2020 |
| Pharmacophore identification and scaffold exploration to discover novel, potent, and chemically stable inhibitors of acid ceramidase in melanoma cells JA Ortega, JM Arencibia, G La Sala, M Borgogno, I Bauer, L Bono, ... Journal of medicinal chemistry 60 (13), 5800-5815, 2017 | 23 | 2017 |
| Novel bacterial topoisomerase inhibitors exploit Asp83 and the intrinsic flexibility of the DNA gyrase binding site S Franco-Ulloa, G La Sala, GP Miscione, M De Vivo International journal of molecular sciences 19 (2), 453, 2018 | 20 | 2018 |
| Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer S Jahid, JA Ortega, LM Vuong, IM Acquistapace, SJ Hachey, JL Flesher, ... Cell reports 39 (1), 2022 | 13 | 2022 |
| Unraveling the allosteric cross-talk between the coactivator peptide and the ligand-binding site in the glucocorticoid receptor G La Sala, A Gunnarsson, K Edman, C Tyrchan, A Hogner, AI Frolov Journal of Chemical Information and Modeling 61 (7), 3667-3680, 2021 | 13 | 2021 |
| Innovative non-PrP-targeted drug strategy designed to enhance prion clearance A Colini Baldeschi, M Zattoni, S Vanni, L Nikolic, C Ferracin, G La Sala, ... Journal of medicinal chemistry 65 (13), 8998-9010, 2022 | 9 | 2022 |
| Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein–Protein Interaction JS Pallesen, CC Munier, F Bosica, SA Andrei, K Edman, A Gunnarsson, ... Journal of medicinal chemistry 65 (24), 16818-16828, 2022 | 6 | 2022 |
| Combining structural and coevolution information to unveil allosteric sites G La Sala, C Pfleger, H Käck, L Wissler, P Nevin, K Böhm, JP Janet, ... Chemical science 14 (25), 7057-7067, 2023 | 4 | 2023 |
| Unravelling Allosteric Cross-Talk between Co-Activator Peptide and Ligand Binding Site in Glucocorticoid Receptor G La Sala, A Gunnarsson, K Edman, C Tyrchan, A Hogner, A Frolov Biophysical Journal 120 (3), 298a, 2021 | 1 | 2021 |
| Structure-based design of CDC42/RHOJ effector inhibitors for the treatment of cancer JL Flesher, S Jahid, JA Ortega, G La Sala, N Brindani, JM Arencibia, ... Cancer Research 80 (16_Supplement), 5324-5324, 2020 | 1 | 2020 |
| Solving the Tubulin Puzzle through Collaborations G La Sala Chem 5 (11), 2740-2741, 2019 | | 2019 |
| Targeting Allosteric Pockets in Protein Kinases Using Molecular Modeling and Simulations G La Sala alma, 2017 | | 2017 |
| Molecular Simulations to Unravel the Allosteric Interplay between the SH2 Domain and A-loop Plasticity in Protein Kinases G La Sala, L Riccardi, R Gaspari, A Cavalli, O Hantschel, M Dal Peraro, ... Biophysical Journal 112 (3), 32a, 2017 | | 2017 |
| Detection and evolution of allosteric pockets and their networks from MD simulations G La Sala, S Decherchi, W Rocchia, M De Vivo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
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