Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function K Yoshioka, K Yoshida, H Cui, T Wakayama, N Takuwa, Y Okamoto, ... Nature medicine 18 (10), 1560-1569, 2012 | 235 | 2012 |
S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species N Takuwa, SI Ohkura, SI Takashima, K Ohtani, Y Okamoto, T Tanaka, ... Cardiovascular research 85 (3), 484-493, 2010 | 163 | 2010 |
S1P2, the G protein–coupled receptor for Sphingosine-1-Phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice W Du, N Takuwa, K Yoshioka, Y Okamoto, K Gonda, K Sugihara, ... Cancer research 70 (2), 772-781, 2010 | 161 | 2010 |
Roles of sphingosine-1-phosphate signaling in angiogenesis Y Takuwa, W Du, X Qi, Y Okamoto, N Takuwa, K Yoshioka World journal of biological chemistry 1 (10), 298, 2010 | 129 | 2010 |
Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice F Wang, Y Okamoto, I Inoki, K Yoshioka, W Du, X Qi, N Takuwa, K Gonda, ... The Journal of clinical investigation 120 (11), 3979-3995, 2010 | 104 | 2010 |
Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms YF Haocheng Lu, Wa Du, Lu Ren, Milton H. Hamblin, Richard C. Becker, Y ... Journal of American Heart Association, 2021 | 99 | 2021 |
Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1—Jekyll Hidden behind Hyde N Takuwa, W Du, E Kaneko, Y Okamoto, K Yoshioka, Y Takuwa American journal of cancer research 1 (4), 460, 2011 | 89 | 2011 |
Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice H Cui, Y Okamoto, K Yoshioka, W Du, N Takuwa, W Zhang, M Asano, ... Journal of allergy and clinical immunology 132 (5), 1205-1214. e9, 2013 | 60 | 2013 |
Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth TL Phung, W Du, Q Xue, S Ayyaswamy, D Gerald, Z Antonello, S Nhek, ... Cancer research 75 (1), 40-50, 2015 | 52 | 2015 |
Vascular tumors have increased p70 S6-kinase activation and are inhibited by topical rapamycin W Du, D Gerald, CA Perruzzi, P Rodriguez-Waitkus, L Enayati, B Krishnan, ... Laboratory investigation 93 (10), 1115-1127, 2013 | 52 | 2013 |
Sustained delivery of sphingosine-1-phosphate using poly (lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation … X Qi, Y Okamoto, T Murakawa, F Wang, O Oyama, R Ohkawa, K Yoshioka, ... European journal of pharmacology 634 (1-3), 121-131, 2010 | 52 | 2010 |
Advances in the medical management of vascular anomalies KW Ricci Seminars in interventional radiology 34 (03), 239-249, 2017 | 42 | 2017 |
Endothelial cell glucose metabolism and angiogenesis W Du, L Ren, MH Hamblin, Y Fan Biomedicines 9 (2), 147, 2021 | 41 | 2021 |
Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice L Ren, W Du, D Song, H Lu, MH Hamblin, C Wang, C Du, GC Fan, ... Iscience 26 (1), 2023 | 5 | 2023 |
Krüppel-like factor 4 supports the expansion of leukemia stem cells in MLL-AF9-driven acute myeloid leukemia AH Lewis, CS Bridges, DN Moorshead, TJ Chen, W Du, B Zorman, ... Stem Cells 40 (8), 736-750, 2022 | 5 | 2022 |
Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia TJ Chen, W Du, JJ Junco, CS Bridges, Y Shen, M Puppi, KR Rabin, ... Oncotarget 12 (18), 1787, 2021 | 5 | 2021 |
Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LRP2-Ssh1 signaling pathway GCF Hongyan Zhao, Peng Wang, Xiaohong Wang, Wa Du, Hui-Hui Yang, Yueying Liu ... Cardiovascular Research, 2023 | 2* | 2023 |
Loss of H2R Signaling Disrupts Neutrophil Homeostasis and Promotes Inflammation-Associated Colonic Tumorigenesis in Mice Z Shi, Y Mori-Akiyama, W Du, R Fultz, Y Zhao, W Ruan, S Venable, ... Cellular and Molecular Gastroenterology and Hepatology 13 (3), 717-737, 2022 | 2 | 2022 |
Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury. FGC Wang X, Du W, Li Y, Yang HH, Zhang Y, Akbar R, Morgan H, Peng T, Chen J ... JCI Insight, 2024 | 1 | 2024 |
Endothelial Cell Glucose Metabolism and Angiogenesis. Biomedicines. 2021; 9: 147 W Du, L Ren, MH Hamblin, Y Fan Endothelial Dysfunction, 67, 2021 | 1 | 2021 |