MyD88-dependent expansion of an immature GR-1+ CD11b+ population induces T cell suppression and Th2 polarization in sepsis MJ Delano, PO Scumpia, JS Weinstein, D Coco, S Nagaraj, ... The Journal of experimental medicine 204 (6), 1463, 2007 | 819 | 2007 |
The immune system's role in sepsis progression, resolution, and long‐term outcome MJ Delano, PA Ward Immunological reviews 274 (1), 330-353, 2016 | 722 | 2016 |
Emerging implications of nanotechnology on cancer diagnostics and therapeutics AG Cuenca, H Jiang, SN Hochwald, M Delano, WG Cance, SR Grobmyer Cancer 107 (3), 459-466, 2006 | 677 | 2006 |
Sepsis-induced immune dysfunction: can immune therapies reduce mortality? MJ Delano, PA Ward The Journal of clinical investigation 126 (1), 23-31, 2016 | 632 | 2016 |
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma AG Cuenca, MJ Delano, KM Kelly-Scumpia, C Moreno, PO Scumpia, ... Molecular medicine 17, 281-292, 2011 | 410 | 2011 |
Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality LM Frydrych, G Bian, DE O’Lone, PA Ward, MJ Delano Journal of leukocyte Biology 104 (3), 525-534, 2018 | 304 | 2018 |
The origins of cachexia in acute and chronic inflammatory diseases MJ Delano, LL Moldawer Nutrition in clinical practice 21 (1), 68-81, 2006 | 261 | 2006 |
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection MJ Delano, T Thayer, S Gabrilovich, KM Kelly-Scumpia, RD Winfield, ... The Journal of Immunology 186 (1), 195-202, 2011 | 206 | 2011 |
B cells enhance early innate immune responses during bacterial sepsis KM Kelly-Scumpia, PO Scumpia, JS Weinstein, MJ Delano, AG Cuenca, ... The Journal of experimental medicine 208 (8), 1673, 2011 | 203 | 2011 |
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists JL Wynn, PO Scumpia, RD Winfield, MJ Delano, K Kelly-Scumpia, ... Blood, The Journal of the American Society of Hematology 112 (5), 1750-1758, 2008 | 189 | 2008 |
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis JL Wynn, PO Scumpia, MJ Delano, KA O'Malley, R Ungaro, A Abouhamze, ... Shock 28 (6), 675-683, 2007 | 172 | 2007 |
Increased natural CD4+ CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis PO Scumpia, MJ Delano, KM Kelly, KA O’Malley, PA Efron, PF McAuliffe, ... The Journal of Immunology 177 (11), 7943-7949, 2006 | 172 | 2006 |
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling MJ Delano, KM Kelly-Scumpia, TC Thayer, RD Winfield, PO Scumpia, ... The Journal of Immunology 187 (2), 911-918, 2011 | 168 | 2011 |
Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling PO Scumpia, KM Kelly-Scumpia, MJ Delano, JS Weinstein, AG Cuenca, ... The Journal of Immunology 184 (5), 2247-2251, 2010 | 162 | 2010 |
Incidence, clinical predictors, genomics, and outcome of acute kidney injury among trauma patients A Bihorac, MJ Delano, JD Schold, MC Lopez, AB Nathens, RV Maier, ... Annals of surgery 252 (1), 158-165, 2010 | 161 | 2010 |
Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab RS Hotchkiss, E Colston, S Yende, ED Crouser, GS Martin, T Albertson, ... Intensive care medicine 45, 1360-1371, 2019 | 156 | 2019 |
Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10 KM Kelly-Scumpia, PO Scumpia, MJ Delano, JS Weinstein, AG Cuenca, ... The Journal of experimental medicine 207 (2), 319, 2010 | 154 | 2010 |
Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes TC Thayer, M Delano, C Liu, J Chen, LE Padgett, HM Tse, M Annamali, ... Diabetes 60 (8), 2144-2151, 2011 | 121 | 2011 |
Diabetes and sepsis: risk, recurrence, and ruination LM Frydrych, F Fattahi, K He, PA Ward, MJ Delano Frontiers in endocrinology 8, 271, 2017 | 104 | 2017 |
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis PO Scumpia, MJ Delano, KM Kelly-Scumpia, JS Weinstein, JL Wynn, ... Blood, The Journal of the American Society of Hematology 110 (10), 3673-3681, 2007 | 97 | 2007 |