Cysteine scanning of CFTR’s first transmembrane segment reveals its plausible roles in gating and permeation X Gao, Y Bai, TC Hwang Biophysical journal 104 (4), 786-797, 2013 | 55 | 2013 |
An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel A Marchesi, X Gao, R Adaixo, J Rheinberger, H Stahlberg, C Nimigean, ... Nature communications 9 (1), 3978, 2018 | 51 | 2018 |
Localizing a gate in CFTR X Gao, TC Hwang Proceedings of the National Academy of Sciences 112 (8), 2461-2466, 2015 | 50 | 2015 |
Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures J Rheinberger, X Gao, PAM Schmidpeter, CM Nimigean Elife 7, e39775, 2018 | 46 | 2018 |
Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK PAM Schmidpeter, X Gao, V Uphadyay, J Rheinberger, CM Nimigean Journal of General Physiology 150 (6), 821-834, 2018 | 28 | 2018 |
Correlation of membrane protein conformational and functional dynamics RR Sanganna Gari, JJ Montalvo‐Acosta, GR Heath, Y Jiang, X Gao, ... Nature Communications 12 (1), 4363, 2021 | 18 | 2021 |
Spatial positioning of CFTR’s pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway X Gao, TC Hwang Journal of General Physiology 147 (5), 407-422, 2016 | 14 | 2016 |
Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel X Gao, PAM Schmidpeter, V Berka, RJ Durham, C Fan, V Jayaraman, ... Nature Communications 13 (1), 6919, 2022 | 5 | 2022 |