Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion Y Lan, M Moustafa, M Knoll, C Xu, J Furkel, A Lazorchak, TL Yeung, ... Cancer cell 39 (10), 1388-1403. e10, 2021 | 129 | 2021 |
Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche S Chiblak, Z Tang, D Lemke, M Knoll, I Dokic, R Warta, M Moustafa, ... JCI insight 4 (2), 2019 | 66 | 2019 |
Synergistic effects of crizotinib and radiotherapy in experimental EML4–ALK fusion positive lung cancer Y Dai, Q Wei, C Schwager, M Moustafa, C Zhou, KE Lipson, W Weichert, ... Radiotherapy and Oncology 114 (2), 173-181, 2015 | 52 | 2015 |
Identification of KIF11 as a novel target in meningioma G Jungwirth, T Yu, M Moustafa, C Rapp, R Warta, C Jungk, F Sahm, ... Cancers 11 (4), 545, 2019 | 40 | 2019 |
Quantitative assessment of radiation dose and fractionation effects on normal tissue by utilizing a novel lung fibrosis index model C Zhou, B Jones, M Moustafa, C Schwager, J Bauer, B Yang, L Cao, M Jia, ... Radiation oncology 12, 1-8, 2017 | 29 | 2017 |
Neuroprotective effects of ultra-high dose rate FLASH Bragg peak proton irradiation I Dokic, S Meister, J Bojcevski, T Tessonnier, D Walsh, M Knoll, S Mein, ... International Journal of Radiation Oncology* Biology* Physics 113 (3), 614-623, 2022 | 28 | 2022 |
KIF11 inhibitors filanesib and ispinesib inhibit meningioma growth in vitro and in vivo G Jungwirth, T Yu, J Cao, MA Eddine, M Moustafa, R Warta, J Debus, ... Cancer Letters 506, 1-10, 2021 | 23 | 2021 |
Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines L Hartmann, P Schröter, W Osen, D Baumann, R Offringa, M Moustafa, ... Scientific reports 10 (1), 21517, 2020 | 15 | 2020 |
Modeling and multiscale characterization of the quantitative imaging based fibrosis index reveals pathophysiological, transcriptome and proteomic correlates of lung fibrosis … C Zhou, MR Moustafa, L Cao, M Kriegsmann, M Winter, C Schwager, ... International journal of cancer 144 (12), 3160-3173, 2019 | 14 | 2019 |
Pharmacological landscape of FDA-approved anticancer drugs reveals sensitivities to ixabepilone, romidepsin, omacetaxine, and carfilzomib in aggressive meningiomas G Jungwirth, T Yu, F Liu, J Cao, M Alaa Eddine, M Moustafa, A Abdollahi, ... Clinical Cancer Research 29 (1), 233-243, 2023 | 12 | 2023 |
Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model L Hartmann, W Osen, OL Eichmüller, T Kordaß, J Furkel, E Dickes, C Reid, ... Cancer Letters 550, 215928, 2022 | 12 | 2022 |
Determining RBE for development of lung fibrosis induced by fractionated irradiation with carbon ions utilizing fibrosis index and high-LET BED model C Zhou, B Jones, M Moustafa, B Yang, S Brons, L Cao, Y Dai, ... Clinical and Translational Radiation Oncology 14, 25-32, 2019 | 12 | 2019 |
Deep Learning–based Automatic Lung Segmentation on Multiresolution CT Scans from Healthy and Fibrotic Lungs in Mice F Sforazzini, P Salome, M Moustafa, C Zhou, C Schwager, K Rein, ... Radiology: Artificial Intelligence 4 (2), e210095, 2022 | 9 | 2022 |
Receptor-tyrosine kinase inhibitor ponatinib inhibits meningioma growth in vitro and in vivo T Yu, J Cao, M Alaa Eddine, M Moustafa, A Mock, C Erkut, A Abdollahi, ... Cancers 13 (23), 5898, 2021 | 9 | 2021 |
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model M Simovic, M Bolkestein, M Moustafa, JKL Wong, V Körber, S Benedetto, ... Neuro-oncology 23 (12), 2028-2041, 2021 | 6 | 2021 |
Therapeutic pamrevlumab (FG-3019) is more effective than pirfenidone or nintedanib in a mouse radiation-induced lung fibrosis model K Lipson, M Moustafa, M Akbarpour, S Fouse, M Kriegsmann, C Zhou, ... European Respiratory Journal 50 (suppl 61), 2017 | 4 | 2017 |
Late intervention with radiation-induced lung fibrosis-comparing Pamrevlumab anti-CTGF therapy vs. Pirfenidone vs. Nintedanib as mono-, dual-and triple-therapy combinations M Moustafa, KE Lipson, M Akbarpour, S Fouse, M Kriegsmann, C Zhou, ... International Journal of Radiation Oncology, Biology, Physics 108 (3), S76, 2020 | 1 | 2020 |
Relative biological effectiveness (RBE) for development of lung fibrosis after single dose carbon ion radiotherapy (CIRT) C Zhou, M Moustafa, Z Zhou, B Jones, S Brons, C Schwager, ... International Journal of Radiation Oncology, Biology, Physics 105 (1), E644-E645, 2019 | 1 | 2019 |
Discovery of histone demethylase KDM5C inactivation as a novel mechanism for tumors resistant to VEGF RTKi via genome-wide in-vivo RNAi A Fahim Golestaneh, M Sun, C Schwager, Z Tang, S Macher-Goeppinger, ... Cancer Research 76 (14_Supplement), 3254-3254, 2016 | 1 | 2016 |
Discovery of histone demethylase KDM5C inactivation as a novel mechanism for tumors resistant to VEGF RTKi via genome-wide in-vivo RNAi AF Golestaneh, M Sun, C Schwager, Z Tang, S Macher-Goeppinger, L Ma, ... CANCER RESEARCH 76, 2016 | 1 | 2016 |