A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research SJ Rihn, A Merits, S Bakshi, ML Turnbull, A Wickenhagen, AJT Alexander, ... PLoS biology 19 (2), e3001091, 2021 | 191 | 2021 |
A prenylated dsRNA sensor protects against severe COVID-19 A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ... Science 374 (6567), eabj3624, 2021 | 161 | 2021 |
A 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site Mutagenesis T Naqvi, AC Warden, N French, E Sugrue, PD Carr, CJ Jackson, C Scott PloS one 9 (4), e94177, 2014 | 43 | 2014 |
TRIM69 inhibits vesicular stomatitis Indiana virus SJ Rihn, MA Aziz, DG Stewart, J Hughes, ML Turnbull, M Varela, ... Journal of virology 93 (20), 10.1128/jvi. 00951-19, 2019 | 37 | 2019 |
Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron E Sugrue, NJ Fraser, DH Hopkins, PD Carr, JL Khurana, JG Oakeshott, ... Applied and environmental microbiology 81 (7), 2612-2624, 2015 | 32 | 2015 |
The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting AE Shaw, SJ Rihn, N Mollentze, A Wickenhagen, DG Stewart, RJ Orton, ... PLoS Biology 19 (9), e3001352, 2021 | 20 | 2021 |
300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization CJ Jackson, CW Coppin, PD Carr, A Aleksandrov, M Wilding, E Sugrue, ... Applied and Environmental Microbiology 80 (13), 4003-4011, 2014 | 19 | 2014 |
A prenylated dsRNA sensor protects against severe COVID-19. Science 374, eabj3624 A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ... | 15 | 2021 |
Constrained evolution of a bispecific enzyme: lessons for biocatalyst design E Sugrue, C Scott, CJ Jackson Organic & biomolecular chemistry 15 (4), 937-946, 2017 | 14 | 2017 |
Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases E Sugrue, PD Carr, C Scott, CJ Jackson Biochemistry 55 (45), 6304-6313, 2016 | 14 | 2016 |
Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application L Esquirol, TS Peat, E Sugrue, S Balotra, S Rottet, AC Warden, M Wilding, ... Advances in Microbial Physiology 76, 129-186, 2020 | 13 | 2020 |
The Evolution of New Catalytic Mechanisms for Xenobiotic Hydrolysis in Bacterial Metalloenzymes E Sugrue, C Hartley, C Scott, C Jackson Australian Journal of Chemistry, 2016 | 7 | 2016 |
The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness E Sugrue, A Wickenhagen, N Mollentze, MA Aziz, VB Sreenu, S Truxa, ... PLoS pathogens 18 (11), e1010973, 2022 | 6 | 2022 |
The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase E Sugrue, D Coombes, D Wood, T Zhu, KA Donovan, RCJ Dobson European Biophysics Journal 49 (8), 761-772, 2020 | 5 | 2020 |
Synthesis, Enantiomeric Resolution and Biological Evaluation of HIV Capsid Inhibition Activity for Racemic,(S)-and (R)-PF74 S Ruddell, E Sugrue, S Memarzadeh, LM Hellam, SJ Wilson, DJ France Molecules 26 (13), 3919, 2021 | 2 | 2021 |
Resurrection of 2′-5′-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication S Lytras, A Wickenhagen, E Sugrue, DG Stewart, S Swingler, A Sims, ... Plos Biology 21 (11), e3002398, 2023 | 1 | 2023 |