Chemogenetics revealed: DREADD occupancy and activation via converted clozapine JL Gomez, J Bonaventura, W Lesniak, WB Mathews, P Sysa-Shah, ... Science 357 (6350), 503-507, 2017 | 993 | 2017 |
Parkin‐independent mitophagy requires D rp1 and maintains the integrity of mammalian heart and brain Y Kageyama, M Hoshijima, K Seo, D Bedja, P Sysa‐Shah, SA Andrabi, ... The EMBO journal 33 (23), 2798-2813, 2014 | 431 | 2014 |
A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors S Chatterjee, WG Lesniak, M Gabrielson, A Lisok, B Wharram, ... Oncotarget 7 (9), 10215, 2016 | 197 | 2016 |
Peptide-based PET quantifies target engagement of PD-L1 therapeutics D Kumar, A Lisok, E Dahmane, M McCoy, S Shelake, S Chatterjee, V Allaj, ... The Journal of clinical investigation 129 (2), 616-630, 2019 | 114 | 2019 |
Imaging CAR T cell therapy with PSMA-targeted positron emission tomography I Minn, DJ Huss, HH Ahn, TM Chinn, A Park, J Jones, M Brummet, ... Science advances 5 (7), eaaw5096, 2019 | 112 | 2019 |
ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity F Belmonte, S Das, P Sysa-Shah, V Sivakumaran, B Stanley, X Guo, ... American Journal of Physiology-Heart and Circulatory Physiology 309 (8 …, 2015 | 108 | 2015 |
A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy D Pramanik, NR Campbell, S Das, S Gupta, V Chenna, S Bisht, ... Oncotarget 3 (6), 640, 2012 | 103 | 2012 |
Transforming growth factor-β1 up-regulation of human α1 (I) collagen is mediated by Sp1 and Smad2 transacting factors P Sysa, JJ Potter, X Liu, E Mezey DNA and cell biology 28 (9), 425-434, 2009 | 76 | 2009 |
Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice P Sysa-Shah, Y Xu, X Guo, F Belmonte, B Kang, D Bedja, S Pin, ... Public Library of Science 7 (8), e42805, 2012 | 65 | 2012 |
[64Cu] XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma I Minn, SM Koo, HS Lee, M Brummet, SP Rowe, MA Gorin, P Sysa-Shah, ... Oncotarget 7 (35), 56471, 2016 | 59 | 2016 |
Imaging of carbonic anhydrase IX with an 111In-labeled dual-motif inhibitor X Yang, I Minn, SP Rowe, SR Banerjee, MA Gorin, M Brummet, HS Lee, ... Oncotarget 6 (32), 33733, 2015 | 53 | 2015 |
Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways P Sysa-Shah, CG Tocchetti, M Gupta, PP Rainer, X Shen, BH Kang, ... Cardiovascular research 109 (3), 358-373, 2016 | 52 | 2016 |
Electrocardiographic characterization of cardiac hypertrophy in mice that overexpress the ErbB2 receptor tyrosine kinase P Sysa-Shah, LL Sørensen, MR Abraham, KL Gabrielson Comparative medicine 65 (4), 295-307, 2015 | 32 | 2015 |
Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis KL Yap, P Sysa-Shah, B Bolon, RC Wu, M Gao, AL Herlinger, F Wang, ... PloS one 8 (7), e69099, 2013 | 25 | 2013 |
Geranylgeranylacetone blocks doxorubicin-induced cardiac toxicity and reduces cancer cell growth and invasion through RHO pathway inhibition P Sysa-Shah, Y Xu, X Guo, S Pin, D Bedja, R Bartock, A Tsao, A Hsieh, ... Molecular cancer therapeutics 13 (7), 1717-1728, 2014 | 21 | 2014 |
Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection FJ Mahmud, Y Du, E Greif, T Boucher, RF Dannals, WB Mathews, ... Journal of Neuroinflammation 17, 1-16, 2020 | 19 | 2020 |
In vivo imaging with confirmation by histopathology for increased rigor and reproducibility in translational research: A review of examples, options, and resources K Gabrielson, R Maronpot, S Monette, C Mlynarczyk, Y Ramot, A Nyska, ... ILAR journal 59 (1), 80-98, 2018 | 17 | 2018 |
Echocardiographic characterization of a murine model of hypertrophic obstructive cardiomyopathy induced by cardiac-specific overexpression of epidermal growth factor receptor 2 LL Sørensen, D Bedja, P Sysa-Shah, H Liu, A Maxwell, X Yi, I Pozios, ... Comparative medicine 66 (4), 268-277, 2016 | 15 | 2016 |
Regulatory Forum Opinion Piece*: Imaging Applications in Toxicologic Pathology—Recommendations for Use in Regulated Nonclinical Toxicity Studies RR Maronpot, A Nyska, SP Troth, K Gabrielson, P Sysa-Shah, ... Toxicologic pathology 45 (4), 444-471, 2017 | 13 | 2017 |
Prenatal stress enhances NNK-induced lung tumors in A/J mice T Ito, H Saeki, X Guo, P Sysa-Shah, J Coulter, KLK Tamashiro, RS Lee, ... Carcinogenesis 41 (12), 1713-1723, 2020 | 6 | 2020 |