All tangled up: how cells direct, manage and exploit topoisomerase function SM Vos, EM Tretter, BH Schmidt, JM Berger Nature reviews Molecular cell biology 12 (12), 827-841, 2011 | 689 | 2011 |
Structure of activated transcription complex Pol II–DSIF–PAF–SPT6 SM Vos, L Farnung, M Boehning, C Wigge, A Linden, H Urlaub, P Cramer Nature 560 (7720), 607-612, 2018 | 372 | 2018 |
Structure of paused transcription complex Pol II–DSIF–NELF SM Vos, L Farnung, H Urlaub, P Cramer Nature 560 (7720), 601-606, 2018 | 335 | 2018 |
Nucleosome–Chd1 structure and implications for chromatin remodelling L Farnung, SM Vos, C Wigge, P Cramer Nature 550 (7677), 539-542, 2017 | 235 | 2017 |
MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation A Baluapuri, J Hofstetter, ND Stankovic, T Endres, P Bhandare, SM Vos, ... Molecular cell 74 (4), 674-687. e11, 2019 | 123 | 2019 |
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction Y Li, NK Stewart, AJ Berger, S Vos, AJ Schoeffler, JM Berger, BT Chait, ... Proceedings of the National Academy of Sciences 107 (44), 18832-18837, 2010 | 120 | 2010 |
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation SM Vos, L Farnung, A Linden, H Urlaub, P Cramer Nature Structural & Molecular Biology 27 (7), 668-677, 2020 | 118 | 2020 |
Structure of transcribing RNA polymerase II-nucleosome complex L Farnung, SM Vos, P Cramer Nature communications 9 (1), 5432, 2018 | 101 | 2018 |
Stress-induced nuclear condensation of NELF drives transcriptional downregulation P Rawat, M Boehning, B Hummel, F Aprile-Garcia, AS Pandit, ... Molecular cell 81 (5), 1013-1026. e11, 2021 | 93 | 2021 |
Structure of a transcribing RNA polymerase II–U1 snRNP complex S Zhang, S Aibara, SM Vos, DE Agafonov, R Lührmann, P Cramer Science 371 (6526), 305-309, 2021 | 86 | 2021 |
Architecture and RNA binding of the human negative elongation factor SM Vos, D Pöllmann, L Caizzi, KB Hofmann, P Rombaut, T Zimniak, ... Elife 5, e14981, 2016 | 72 | 2016 |
RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases S Battaglia, M Lidschreiber, C Baejen, P Torkler, SM Vos, P Cramer Elife 6, e25637, 2017 | 61 | 2017 |
Structural basis of nucleosome retention during transcription elongation M Filipovski, JHM Soffers, SM Vos, L Farnung Science 376 (6599), 1313-1316, 2022 | 49 | 2022 |
Structure of a backtracked hexasomal intermediate of nucleosome transcription L Farnung, M Ochmann, G Garg, SM Vos, P Cramer Molecular Cell 82 (17), 3126-3134. e7, 2022 | 41 | 2022 |
Drugging the “undruggable” MYCN oncogenic transcription factor: overcoming previous obstacles to impact childhood cancers AJ Wolpaw, R Bayliss, G Büchel, CV Dang, M Eilers, WC Gustafson, ... Cancer research 81 (7), 1627-1632, 2021 | 40 | 2021 |
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters T Endres, D Solvie, JB Heidelberger, V Andrioletti, A Baluapuri, CP Ade, ... Molecular cell 81 (4), 830-844. e13, 2021 | 36 | 2021 |
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts D Papadopoulos, D Solvie, A Baluapuri, T Endres, SA Ha, S Herold, ... Molecular cell 82 (1), 159-176. e12, 2022 | 34 | 2022 |
Structural basis for the MukB‐topoisomerase IV interaction and its functional implications in vivo SM Vos, NK Stewart, MG Oakley, JM Berger The EMBO journal 32 (22), 2950-2962, 2013 | 33 | 2013 |
Assembly of RNA polymerase II transcription initiation complexes L Farnung, SM Vos Current opinion in structural biology 73, 102335, 2022 | 27 | 2022 |
Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein SM Vos, AY Lyubimov, DM Hershey, AJ Schoeffler, S Sengupta, ... Genes & development 28 (13), 1485-1497, 2014 | 23 | 2014 |