Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system DL Akey, WC Brown, S Dutta, J Konwerski, J Jose, TJ Jurkiw, ... Science 343 (6173), 881-885, 2014 | 413 | 2014 |
Extended surface for membrane association in Zika virus NS1 structure WC Brown, DL Akey, JR Konwerski, JT Tarrasch, G Skiniotis, RJ Kuhn, ... Nature structural & molecular biology 23 (9), 865-867, 2016 | 191 | 2016 |
Buried Polar Residues in Coiled-Coil Interfaces, DL Akey, VN Malashkevich, PS Kim Biochemistry 40 (21), 6352-6360, 2001 | 171 | 2001 |
Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway DL Akey, JR Razelun, J Tehranisa, DH Sherman, WH Gerwick, JL Smith Structure 18 (1), 94-105, 2010 | 152 | 2010 |
Structural basis for macrolactonization by the pikromycin thioesterase DL Akey, JD Kittendorf, JW Giraldes, RA Fecik, DH Sherman, JL Smith Nature chemical biology 2 (10), 537-542, 2006 | 144 | 2006 |
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis JD Mougous, CJ Petzold, RH Senaratne, DH Lee, DL Akey, FL Lin, ... Nature structural & molecular biology 11 (8), 721-729, 2004 | 126 | 2004 |
Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels JW Giraldes, DL Akey, JD Kittendorf, DH Sherman, JL Smith, RA Fecik Nature Chemical Biology 2 (10), 531-536, 2006 | 108 | 2006 |
Structure‐guided insights on the role of NS1 in flavivirus infection DL Akey, WC Brown, J Jose, RJ Kuhn, JL Smith Bioessays 37 (5), 489-494, 2015 | 107 | 2015 |
Structure and functional analysis of RifR, the type II thioesterase from the rifamycin biosynthetic pathway HB Claxton, DL Akey, MK Silver, SJ Admiraal, JL Smith Journal of Biological Chemistry 284 (8), 5021-5029, 2009 | 99 | 2009 |
Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction SB Biering, DL Akey, MP Wong, WC Brown, NTN Lo, H Puerta-Guardo, ... Science 371 (6525), 194-200, 2021 | 98 | 2021 |
The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins R Fennell‐Fezzie, SD Gradia, D Akey, JM Berger The EMBO journal 24 (11), 1921-1930, 2005 | 90 | 2005 |
A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules R Sanishvili, V Nagarajan, D Yoder, M Becker, S Xu, S Corcoran, DL Akey, ... Acta Crystallographica Section D: Biological Crystallography 64 (4), 425-435, 2008 | 85 | 2008 |
The oligomeric state of CtBP determines its role as a transcriptional co‐activator and co‐repressor of Wingless targets C Bhambhani, JL Chang, DL Akey, KM Cadigan The EMBO journal 30 (10), 2031-2043, 2011 | 75 | 2011 |
Thiosulfate sulfurtransferase-like domain–containing 1 protein interacts with thioredoxin M Libiad, N Motl, DL Akey, N Sakamoto, ER Fearon, JL Smith, R Banerjee Journal of Biological Chemistry 293 (8), 2675-2686, 2018 | 73 | 2018 |
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor JA Chemler, TJ Buchholz, TW Geders, DL Akey, CM Rath, GE Chlipala, ... Journal of the American Chemical Society 134 (17), 7359-7366, 2012 | 73 | 2012 |
Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D D Akey, A Martins, J Aniukwu, MS Glickman, S Shuman, JM Berger Journal of Biological Chemistry 281 (19), 13412-13423, 2006 | 73 | 2006 |
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase JB Scaglione, DL Akey, R Sullivan, JD Kittendorf, CM Rath, ES Kim, ... Angewandte Chemie (International ed. in English) 49 (33), 5726, 2010 | 69 | 2010 |
Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å DL Akey, JM Berger Protein science 14 (10), 2744-2750, 2005 | 44 | 2005 |
Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing TC Terwilliger, G Bunkóczi, LW Hung, PH Zwart, JL Smith, DL Akey, ... Acta Crystallographica Section D: Structural Biology 72 (3), 346-358, 2016 | 35 | 2016 |
Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal TC Terwilliger, G Bunkóczi, LW Hung, PH Zwart, JL Smith, DL Akey, ... Acta Crystallographica Section D: Structural Biology 72 (3), 359-374, 2016 | 33 | 2016 |