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David Akey
David Akey
在 umich.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system
DL Akey, WC Brown, S Dutta, J Konwerski, J Jose, TJ Jurkiw, ...
Science 343 (6173), 881-885, 2014
4132014
Extended surface for membrane association in Zika virus NS1 structure
WC Brown, DL Akey, JR Konwerski, JT Tarrasch, G Skiniotis, RJ Kuhn, ...
Nature structural & molecular biology 23 (9), 865-867, 2016
1912016
Buried Polar Residues in Coiled-Coil Interfaces,
DL Akey, VN Malashkevich, PS Kim
Biochemistry 40 (21), 6352-6360, 2001
1712001
Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway
DL Akey, JR Razelun, J Tehranisa, DH Sherman, WH Gerwick, JL Smith
Structure 18 (1), 94-105, 2010
1522010
Structural basis for macrolactonization by the pikromycin thioesterase
DL Akey, JD Kittendorf, JW Giraldes, RA Fecik, DH Sherman, JL Smith
Nature chemical biology 2 (10), 537-542, 2006
1442006
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis
JD Mougous, CJ Petzold, RH Senaratne, DH Lee, DL Akey, FL Lin, ...
Nature structural & molecular biology 11 (8), 721-729, 2004
1262004
Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels
JW Giraldes, DL Akey, JD Kittendorf, DH Sherman, JL Smith, RA Fecik
Nature Chemical Biology 2 (10), 531-536, 2006
1082006
Structure‐guided insights on the role of NS1 in flavivirus infection
DL Akey, WC Brown, J Jose, RJ Kuhn, JL Smith
Bioessays 37 (5), 489-494, 2015
1072015
Structure and functional analysis of RifR, the type II thioesterase from the rifamycin biosynthetic pathway
HB Claxton, DL Akey, MK Silver, SJ Admiraal, JL Smith
Journal of Biological Chemistry 284 (8), 5021-5029, 2009
992009
Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction
SB Biering, DL Akey, MP Wong, WC Brown, NTN Lo, H Puerta-Guardo, ...
Science 371 (6525), 194-200, 2021
982021
The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins
R Fennell‐Fezzie, SD Gradia, D Akey, JM Berger
The EMBO journal 24 (11), 1921-1930, 2005
902005
A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules
R Sanishvili, V Nagarajan, D Yoder, M Becker, S Xu, S Corcoran, DL Akey, ...
Acta Crystallographica Section D: Biological Crystallography 64 (4), 425-435, 2008
852008
The oligomeric state of CtBP determines its role as a transcriptional co‐activator and co‐repressor of Wingless targets
C Bhambhani, JL Chang, DL Akey, KM Cadigan
The EMBO journal 30 (10), 2031-2043, 2011
752011
Thiosulfate sulfurtransferase-like domain–containing 1 protein interacts with thioredoxin
M Libiad, N Motl, DL Akey, N Sakamoto, ER Fearon, JL Smith, R Banerjee
Journal of Biological Chemistry 293 (8), 2675-2686, 2018
732018
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor
JA Chemler, TJ Buchholz, TW Geders, DL Akey, CM Rath, GE Chlipala, ...
Journal of the American Chemical Society 134 (17), 7359-7366, 2012
732012
Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D
D Akey, A Martins, J Aniukwu, MS Glickman, S Shuman, JM Berger
Journal of Biological Chemistry 281 (19), 13412-13423, 2006
732006
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase
JB Scaglione, DL Akey, R Sullivan, JD Kittendorf, CM Rath, ES Kim, ...
Angewandte Chemie (International ed. in English) 49 (33), 5726, 2010
692010
Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å
DL Akey, JM Berger
Protein science 14 (10), 2744-2750, 2005
442005
Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing
TC Terwilliger, G Bunkóczi, LW Hung, PH Zwart, JL Smith, DL Akey, ...
Acta Crystallographica Section D: Structural Biology 72 (3), 346-358, 2016
352016
Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal
TC Terwilliger, G Bunkóczi, LW Hung, PH Zwart, JL Smith, DL Akey, ...
Acta Crystallographica Section D: Structural Biology 72 (3), 359-374, 2016
332016
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