Upstream open reading frames differentially regulate gene-specific translation in the integrated stress response SK Young, RC Wek Journal of Biological Chemistry 291 (33), 16927-16935, 2016 | 377 | 2016 |
CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis JA Willy, SK Young, JL Stevens, HC Masuoka, RC Wek Molecular biology of the cell 26 (12), 2190-2204, 2015 | 140 | 2015 |
Polyamine control of translation elongation regulates start site selection on antizyme inhibitor mRNA via ribosome queuing IP Ivanov, BS Shin, G Loughran, I Tzani, SK Young-Baird, C Cao, ... Molecular cell 70 (2), 254-264. e6, 2018 | 130 | 2018 |
Ribosome reinitiation directs gene-specific translation and regulates the integrated stress response SK Young, JA Willy, C Wu, MS Sachs, RC Wek Journal of Biological Chemistry 290 (47), 28257-28271, 2015 | 100 | 2015 |
Ribosome elongation stall directs gene-specific translation in the integrated stress response SK Young, LR Palam, C Wu, MS Sachs, RC Wek Journal of Biological Chemistry 291 (12), 6546-6558, 2016 | 74 | 2016 |
Spiteful interactions between sympatric natural isolates of Xenorhabdus bovienii benefit kin and reduce virulence F Bashey, SK Young, H Hawlena, CM Lively Journal of evolutionary biology 25 (3), 431-437, 2012 | 45 | 2012 |
Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation LC Gregory, CB Ferreira, SK Young-Baird, HJ Williams, M Harakalova, ... EBioMedicine 42, 470-480, 2019 | 44 | 2019 |
Translation regulation of the glutamyl-prolyl-tRNA synthetase gene EPRS through bypass of upstream open reading frames with noncanonical initiation codons SK Young, TD Baird, RC Wek Journal of Biological Chemistry 291 (20), 10824-10835, 2016 | 40 | 2016 |
Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB SK Young-Baird, MB Lourenço, MK Elder, E Klann, S Liebau, TE Dever Molecular Cell 77 (4), 875-886. e7, 2020 | 39 | 2020 |
Bmi1 promotes erythroid development through regulating ribosome biogenesis R Gao, S Chen, M Kobayashi, H Yu, Y Zhang, Y Wan, SK Young, A Soltis, ... Stem cells 33 (3), 925-938, 2015 | 37 | 2015 |
MEHMO syndrome mutation EIF2S3-I259M impairs initiator Met-tRNAiMet binding to eukaryotic translation initiation factor eIF2 SK Young-Baird, BS Shin, TE Dever Nucleic acids research 47 (2), 855-867, 2018 | 28 | 2018 |
Nuclear matrix protein 4 is a novel regulator of ribosome biogenesis and controls the unfolded protein response via repression of Gadd34 expression SK Young, Y Shao, JP Bidwell, RC Wek Journal of Biological Chemistry 291 (26), 13780-13788, 2016 | 24 | 2016 |
Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response JA Willy, SK Young, AL Mosley, S Gawrieh, JL Stevens, HC Masuoka, ... Journal of Biological Chemistry 292 (34), 14050-14065, 2017 | 23 | 2017 |
Virulence and competitive ability in an obligately killing parasite F Bashey, C Reynolds, T Sarin, SK Young Oikos 120 (10), 1539-1545, 2011 | 23 | 2011 |
Eltrombopag Improves Erythroid Differentiation in a Human Induced Pluripotent Stem Cell Model of Diamond Blackfan Anemia H Qanash, Y Li, RH Smith, K Linask, S Young-Baird, W Hakami, ... Cells 10 (4), 734, 2021 | 12 | 2021 |
Novel pathogenic EIF2S3 missense variants causing clinically variable MEHMO syndrome with impaired eIF2γ translational function, and literature review U Kotzaeridou, SK Young‐Baird, V Suckow, AG Thornburg, M Wagner, ... Clinical Genetics 98 (5), 507-514, 2020 | 12 | 2020 |
Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell–extrinsic contributions to erythropoiesis RT Doty, X Fan, DJ Young, J Liang, K Singh, Z Pakbaz, R Desmond, ... Blood, The Journal of the American Society of Hematology 139 (23), 3439-3449, 2022 | 11 | 2022 |
Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes SK Young-Baird Journal of Biological Chemistry 299 (1), 2023 | 1 | 2023 |