Enantioselective hydrogenation of olefins with iridium–phosphanodihydrooxazole catalysts A Lightfoot, P Schnider, A Pfaltz Angewandte Chemie International Edition 37 (20), 2897-2899, 1998 | 624 | 1998 |
Enantioselective hydrogenation of imines with chiral (phosphanodihydrooxazole) iridium catalysts P Schnider, G Koch, R Prétôt, G Wang, FM Bohnen, C Krüger, A Pfaltz Chemistry–A European Journal 3 (6), 887-892, 1997 | 348 | 1997 |
Pharmacological promiscuity: dependence on compound properties and target specificity in a set of recent Roche compounds JU Peters, P Schnider, P Mattei, M Kansy ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 680-686, 2009 | 176 | 2009 |
Enantioselective hydrogenation of olefins with phosphinooxazoline‐iridium catalysts DG Blackmond, A Lightfoot, A Pfaltz, T Rosner, P Schnider, ... Chirality: The Pharmacological, Biological, and Chemical Consequences of …, 2000 | 166 | 2000 |
Enantioselektive Hydrierung von Olefinen mit Phosphandihydrooxazol‐Iridium‐Katalysatoren A Lightfoot, P Schnider, A Pfaltz Angewandte Chemie 110 (20), 3047-3050, 1998 | 143 | 1998 |
Greatly Simplified Procedures for the Synthesis of α-Amino Acids by the Direct Alkylation of Pseudoephedrine Glycinamide Hydrate AG Myers, P Schnider, S Kwon, DW Kung The Journal of organic chemistry 64 (9), 3322-3327, 1999 | 107 | 1999 |
Synthesis of chiral (phosphinoaryl) oxazolines, a versatile class of ligands for asymmetric catalysis G Koch, GC Lloyd‐Jones, O Loiseleur, A Pfaltz, R Prétôt, S Schaffner, ... Recueil des Travaux Chimiques des Pays‐Bas 114 (4‐5), 206-210, 1995 | 100 | 1995 |
4-phenyl-pyridine derivatives M Bös, Q Branca, G Galley, T Godel, T Hoffmann, W Hunkeler, P Schnider, ... US Patent 6,297,375, 2001 | 72 | 2001 |
4-phenyl-pyridine derivatives M Bös, Q Branca, G Galley, T Godel, T Hoffmann, W Hunkeler, P Schnider, ... US Patent 6,479,483, 2002 | 68 | 2002 |
NK-1 receptor active amine oxide prodrugs T Hoffmann, SM Poli, P Schnider, A Sleight US Patent 6,593,472, 2003 | 59 | 2003 |
Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists T Hoffmann, M Bös, H Stadler, P Schnider, W Hunkeler, T Godel, G Galley, ... Bioorganic & medicinal chemistry letters 16 (5), 1362-1365, 2006 | 55 | 2006 |
Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder P Schnider, C Bissantz, A Bruns, C Dolente, E Goetschi, R Jakob-Roetne, ... Journal of Medicinal Chemistry 63 (4), 1511-1525, 2020 | 54 | 2020 |
Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach H Ratni, M Rogers-Evans, C Bissantz, C Grundschober, JL Moreau, ... Journal of medicinal chemistry 58 (5), 2275-2289, 2015 | 52 | 2015 |
Substituted 4-phenyl-pyridine compounds with activity as antagonists of neurokinin 1 receptors T Godel, T Hoffmann, P Schnider, H Stadler US Patent 6,770,637, 2004 | 45 | 2004 |
Process for the preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carbocyclic acids S Bachmann, M Scalone, P Schnider US Patent App. 11/731,191, 2007 | 43 | 2007 |
Indol-3-y-carbonyl-piperidin and piperazin-derivatives C Bissantz, C Grundschober, H Ratni, M Rogers-Evans, P Schnider US Patent 7,781,436, 2010 | 24 | 2010 |
Indol-3-yl-carbonyl-spiro-piperidine derivatives C Bissantz, C Grundschober, H Ratni, M Rogers-Evans, P Schnider US Patent 7,351,706, 2008 | 22 | 2008 |
t, G. Wang, FM Bohnen, C. Kr∏ ger, A. Pfaltz P Schnider, G Koch, R Pre Chem. Eur. J 3, 887-892, 1997 | 21 | 1997 |
ROCK: the Roche medicinal chemistry knowledge application–design, use and impact A Mayweg, U Hofer, P Schnider, F Agnetti, G Galley, P Mattei, M Lucas, ... Drug discovery today 16 (15-16), 691-696, 2011 | 20 | 2011 |
Indol-3-y-carbonyl-piperidin and piperazin-derivatives C Bissantz, C Grundschober, H Ratni, M Rogers-Evans, P Schnider US Patent App. 12/779,099, 2010 | 19 | 2010 |