Targeting of ion channels to membrane microdomains: localization of KV channels to lipid rafts JR Martens, K O'Connell, M Tamkun Trends in pharmacological sciences 25 (1), 16-21, 2004 | 221 | 2004 |
Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus SB Baver, K Hope, S Guyot, C Bjørbaek, C Kaczorowski, KMS O'Connell Journal of Neuroscience 34 (16), 5486-5496, 2014 | 212 | 2014 |
Harnessing genetic complexity to enhance translatability of Alzheimer’s disease mouse models: a path toward precision medicine SM Neuner, SE Heuer, MJ Huentelman, KMS O’Connell, CC Kaczorowski Neuron 101 (3), 399-411. e5, 2019 | 182 | 2019 |
Kv2. 1 potassium channels are retained within dynamic cell surface microdomains that are defined by a perimeter fence KMS O'Connell, AS Rolig, JD Whitesell, MM Tamkun Journal of Neuroscience 26 (38), 9609-9618, 2006 | 144 | 2006 |
Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling RG Weiss, KMS O’Connell, BE Flucher, PD Allen, M Grabner, RT Dirksen American Journal of Physiology-Cell Physiology 287 (4), C1094-C1102, 2004 | 144 | 2004 |
Localization-dependent activity of the Kv2. 1 delayed-rectifier K+ channel KMS O'Connell, R Loftus, MM Tamkun Proceedings of the National Academy of Sciences 107 (27), 12351-12356, 2010 | 143 | 2010 |
Targeting of voltage-gated potassium channel isoforms to distinct cell surface microdomains KMS O'Connell, MM Tamkun Journal of cell science 118 (10), 2155-2166, 2005 | 143 | 2005 |
Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease AR Dunn, KMS O’Connell, CC Kaczorowski Neuroscience & Biobehavioral Reviews 103, 73-80, 2019 | 127 | 2019 |
Localization of ion channels to lipid Raft domains within the cardiovascular system KMS O'Connell, JR Martens, MM Tamkun Trends in cardiovascular medicine 14 (2), 37-42, 2004 | 115 | 2004 |
A cytoskeletal-based perimeter fence selectively corrals a sub-population of cell surface Kv2. 1 channels MM Tamkun, KMS O'connell, AS Rolig Journal of cell science 120 (14), 2413-2423, 2007 | 109 | 2007 |
The pore region of the skeletal muscle ryanodine receptor is a primary locus for excitation-contraction uncoupling in central core disease G Avila, KMS O'Connell, RT Dirksen The Journal of general physiology 121 (4), 277-286, 2003 | 90 | 2003 |
TRPC3 channels critically regulate hippocampal excitability and contextual fear memory SM Neuner, LA Wilmott, KA Hope, B Hoffmann, JA Chong, J Abramowitz, ... Behavioural brain research 281, 69-77, 2015 | 68 | 2015 |
Ca2+ release through ryanodine receptors regulates skeletal muscle L-type Ca2+ channel expression G Avila, KMS O'Connell, LA Groom, RT Dirksen Journal of Biological Chemistry 276 (21), 17732-17738, 2001 | 57 | 2001 |
Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice W Wei, K Pham, JW Gammons, D Sutherland, Y Liu, A Smith, ... Scientific reports 5 (1), 16810, 2015 | 54 | 2015 |
Localization and mobility of the delayed-rectifer K+ channel Kv2.1 in adult cardiomyocytes KMS O'Connell, JD Whitesell, MM Tamkun American Journal of Physiology-Heart and Circulatory Physiology 294 (1 …, 2008 | 52 | 2008 |
Calmodulin binding to the 3614–3643 region of RyR1 is not essential for excitation–contraction coupling in skeletal myotubes KMS O'Connell, N Yamaguchi, G Meissner, RT Dirksen The Journal of general physiology 120 (3), 337-347, 2002 | 38 | 2002 |
Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging SM Neuner, BP Garfinkel, LA Wilmott, BM Ignatowska-Jankowska, A Citri, ... Neurobiology of aging 46, 58-67, 2016 | 37 | 2016 |
Translational approaches to understanding resilience to Alzheimer’s disease SM Neuner, M Telpoukhovskaia, V Menon, KMS O’Connell, TJ Hohman, ... Trends in neurosciences 45 (5), 369-383, 2022 | 36 | 2022 |
The C-terminus of neuronal Kv2. 1 channels is required for channel localization and targeting but not for NMDA-receptor-mediated regulation of channel function SB Baver, KMS O’Connell Neuroscience 217, 56-66, 2012 | 27 | 2012 |
Suramin interacts with the calmodulin binding site on the ryanodine receptor, RYR1 RVL Papineni, KMS O'Connell, H Zhang, RT Dirksen, SL Hamilton Journal of Biological Chemistry 277 (51), 49167-49174, 2002 | 27 | 2002 |