关注
Arvin Iracheta-Vellve
Arvin Iracheta-Vellve
Senior Scientist
在 umassmed.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
5212019
STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
J Petrasek, A Iracheta-Vellve, T Csak, A Satishchandran, K Kodys, ...
Proceedings of the National Academy of Sciences 110 (41), 16544-16549, 2013
3982013
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ...
Nature 595 (7866), 309-314, 2021
2282021
Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol‐induced liver damage, steatosis, and inflammation in mice
A Ambade, P Lowe, K Kodys, D Catalano, B Gyongyosi, Y Cho, ...
Hepatology 69 (3), 1105-1121, 2019
1752019
Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease
J Petrasek, A Iracheta-Vellve, B Saha, A Satishchandran, K Kodys, ...
Journal of Leucocyte Biology 98 (2), 249-256, 2015
1702015
Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via stimulator of interferon genes
A Iracheta-Vellve, J Petrasek, B Gyongyosi, A Satishchandran, P Lowe, ...
Journal of Biological Chemistry 291 (52), 26794-26805, 2016
1432016
MicroRNA 122, regulated by GRLH2, protects livers of mice and patients from ethanol-induced liver disease
A Satishchandran, A Ambade, S Rao, YC Hsueh, A Iracheta-Vellve, ...
Gastroenterology 154 (1), 238-252. e7, 2018
1412018
Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice
A Iracheta-Vellve, J Petrasek, A Satishchandran, B Gyongyosi, B Saha, ...
Journal of hepatology 63 (5), 1147-1155, 2015
1402015
Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure
SJ Patel, JM Milwid, KR King, S Bohr, A Iracheta-Vellve, M Li, A Vitalo, ...
Nature biotechnology 30 (2), 179-183, 2012
1402012
Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use
TN Bukong, Y Cho, A Iracheta-Vellve, B Saha, P Lowe, A Adejumo, I Furi, ...
Journal of Hepatology 69 (5), 1145-1154, 2018
1232018
Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90
B Saha, F Momen‐Heravi, I Furi, K Kodys, D Catalano, A Gangopadhyay, ...
Hepatology 67 (5), 1986-2000, 2018
1172018
Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice
PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, A Ambade, ...
PloS one 12 (3), e0174544, 2017
1172017
Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression
PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, Y Cho, ...
Journal of neuroinflammation 15, 1-12, 2018
1112018
Macrophage‐specific hypoxia‐inducible factor‐1α contributes to impaired autophagic flux in nonalcoholic steatohepatitis
X Wang, M de Carvalho Ribeiro, A Iracheta‐Vellve, P Lowe, A Ambade, ...
Hepatology 69 (2), 545-563, 2019
1022019
MicroRNA-155 deficiency attenuates liver steatosis and fibrosis without reducing inflammation in a mouse model of steatohepatitis
T Csak, S Bala, D Lippai, K Kodys, D Catalano, A Iracheta-Vellve, ...
PLoS One 10 (6), e0129251, 2015
972015
FXR and TGR5 agonists ameliorate liver injury, steatosis, and inflammation after binge or prolonged alcohol feeding in mice
A Iracheta‐Vellve, CD Calenda, J Petrasek, A Ambade, K Kodys, ...
Hepatology communications 2 (11), 1379-1391, 2018
912018
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
J Dubrot, PP Du, SK Lane-Reticker, EA Kessler, AJ Muscato, A Mehta, ...
Nature Immunology 23 (10), 1495-1506, 2022
882022
Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease
S Bala, T Csak, K Kodys, D Catalano, A Ambade, I Furi, P Lowe, Y Cho, ...
Journal of Leukocyte Biology 102 (2), 487-498, 2017
862017
Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease
TN Bukong, A Iracheta‐Vellve, B Saha, A Ambade, A Satishchandran, ...
Hepatology 64 (4), 1057-1071, 2016
712016
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma
J Dubrot, SK Lane-Reticker, EA Kessler, A Ayer, G Mishra, CH Wolfe, ...
Immunity 54 (3), 571-585. e6, 2021
662021
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