Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system A Taly, PJ Corringer, D Guedin, P Lestage, JP Changeux Nature reviews Drug discovery 8 (9), 733-750, 2009 | 831 | 2009 |
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family N Bocquet, L Prado de Carvalho, J Cartaud, J Neyton, C Le Poupon, ... Nature 445 (7123), 116-119, 2007 | 350 | 2007 |
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism A Taly, M Delarue, T Grutter, M Nilges, N Le Novere, PJ Corringer, ... Biophysical journal 88 (6), 3954-3965, 2005 | 233 | 2005 |
Ligand-gated ion channels: new insights into neurological disorders and ligand recognition D Lemoine, R Jiang, A Taly, T Chataigneau, A Specht, T Grutter Chemical reviews 112 (12), 6285-6318, 2012 | 184 | 2012 |
The plastid terminal oxidase: its elusive function points to multiple contributions to plastid physiology WJ Nawrocki, NJ Tourasse, A Taly, F Rappaport, FA Wollman Annual review of plant biology 66, 49-74, 2015 | 175 | 2015 |
A gating mechanism of pentameric ligand-gated ion channels N Calimet, M Simoes, JP Changeux, M Karplus, A Taly, M Cecchini Proceedings of the National Academy of Sciences 110 (42), E3987-E3996, 2013 | 160 | 2013 |
Nicotinic receptors, allosteric proteins and medicine JP Changeux, A Taly Trends in molecular medicine 14 (3), 93-102, 2008 | 149 | 2008 |
Molecular tuning of fast gating in pentameric ligand-gated ion channels T Grutter, LP de Carvalho, V Dufresne, A Taly, SJ Edelstein, JP Changeux Proceedings of the National Academy of Sciences 102 (50), 18207-18212, 2005 | 136 | 2005 |
Evolution of pentameric ligand-gated ion channels: Pro-loop receptors M Jaiteh, A Taly, J Hénin PloS one 11 (3), e0151934, 2016 | 118 | 2016 |
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors A Taly, PJ Corringer, T Grutter, LP de Carvalho, M Karplus, JP Changeux Proceedings of the National Academy of Sciences 103 (45), 16965-16970, 2006 | 109 | 2006 |
Tightening of the ATP‐binding sites induces the opening of P2X receptor channels R Jiang, A Taly, D Lemoine, A Martz, O Cunrath, T Grutter The EMBO Journal 31 (9), 2134-2143, 2012 | 92 | 2012 |
XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy V Camus, H Miloudi, A Taly, B Sola, F Jardin Journal of Hematology & Oncology 10 (47), 1-13, 2017 | 86 | 2017 |
Moving through the gate in ATP-activated P2X receptors R Jiang, A Taly, T Grutter Trends in biochemical sciences 38 (1), 20-29, 2013 | 83 | 2013 |
Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor É Lörinczi, Y Bhargava, SF Marino, A Taly, K Kaczmarek-Hájek, ... Proceedings of the National Academy of Sciences 109 (28), 11396-11401, 2012 | 78 | 2012 |
Optical control of an ion channel gate D Lemoine, C Habermacher, A Martz, PF Méry, N Bouquier, F Diverchy, ... Proceedings of the National Academy of Sciences 110 (51), 20813-20818, 2013 | 74 | 2013 |
Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain S Zhu, D Stroebel, CA Yao, A Taly, P Paoletti Nature structural & molecular biology 20 (4), 477-485, 2013 | 68 | 2013 |
Agonist trapped in ATP-binding sites of the P2X2 receptor R Jiang, D Lemoine, A Martz, A Taly, S Gonin, L Prado de Carvalho, ... Proceedings of the National Academy of Sciences 108 (22), 9066-9071, 2011 | 60 | 2011 |
Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure G Moraga-Cid, L Sauguet, C Huon, L Malherbe, C Girard-Blanc, S Petres, ... Proceedings of the National Academy of Sciences 112 (9), 2865-2870, 2015 | 57 | 2015 |
A mutation causes MuSK reduced sensitivity to agrin and congenital myasthenia A Ben Ammar, P Soltanzadeh, S Bauché, P Richard, E Goillot, R Herbst, ... PLoS One 8 (1), e53826, 2013 | 52 | 2013 |
A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor R Jiang, A Martz, S Gonin, A Taly, LP de Carvalho, T Grutter Journal of biological chemistry 285 (21), 15805-15815, 2010 | 49 | 2010 |