FSP1 is a glutathione-independent ferroptosis suppressor S Doll, FP Freitas, R Shah, M Aldrovandi, MC da Silva, I Ingold, ... Nature 575 (7784), 693-698, 2019 | 2078 | 2019 |
Filamins: promiscuous organizers of the cytoskeleton GM Popowicz, M Schleicher, AA Noegel, TA Holak Trends in biochemical sciences 31 (7), 411-419, 2006 | 346 | 2006 |
Structure of the stapled p53 peptide bound to Mdm2 S Baek, PS Kutchukian, GL Verdine, R Huber, TA Holak, KW Lee, ... Journal of the American Chemical Society 134 (1), 103-106, 2012 | 296 | 2012 |
Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery GM Popowicz, A Czarna, S Wolf, K Wang, W Wang, A Dömling, TA Holak Cell cycle 9 (6), 1104-1111, 2010 | 290 | 2010 |
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain G Popowicz, A Czarna, T Holak Cell cycle 7 (15), 2441-2443, 2008 | 229 | 2008 |
The structure‐based design of MDM2/MDMX–p53 inhibitors gets serious GM Popowicz, A Dömling, TA Holak Angewandte Chemie International Edition 50 (12), 2680-2688, 2011 | 193 | 2011 |
Molecular basis for the inhibition of p53 by Mdmx GM Popowicz, A Czarna, U Rothweiler, A Szwagierczak, M Krajewski, ... Cell cycle 6 (19), 2386-2392, 2007 | 178 | 2007 |
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins T Sitar, GM Popowicz, I Siwanowicz, R Huber, TA Holak Proceedings of the National Academy of Sciences 103 (35), 13028-13033, 2006 | 171 | 2006 |
Robust generation of lead compounds for protein-protein interactions by computational and MCR chemistry: p53-Hdm2 antagonists A Czarna, B Beck, S Srivastava, G Popowicz, S Wolf, Y Huang, M Bista, ... Angewandte Chemie (International ed. in English) 49 (31), 5352, 2010 | 162 | 2010 |
The crystal structure of the non-liganded 14-3-3σ protein: insights into determinants of isoform specific ligand binding and dimerization A Benzinger, GM Popowicz, JK Joy, S Majumdar, TA Holak, H Hermeking Cell research 15 (4), 219-227, 2005 | 154 | 2005 |
High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx A Czarna, GM Popowicz, A Pecak, S Wolf, G Dubin, TA Holak Cell cycle 8 (8), 1176-1184, 2009 | 127 | 2009 |
Structural basis for the assembly of the Sxl–Unr translation regulatory complex J Hennig, C Militti, GM Popowicz, I Wang, M Sonntag, A Geerlof, F Gabel, ... Nature 515 (7526), 287-290, 2014 | 123 | 2014 |
Enabling large-scale design, synthesis and validation of small molecule protein-protein antagonists D Koes, K Khoury, Y Huang, W Wang, M Bista, GM Popowicz, S Wolf, ... PloS one 7 (3), e32839, 2012 | 120 | 2012 |
Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing SK Mishra, T Ammon, GM Popowicz, M Krajewski, RJ Nagel, M Ares, ... Nature 474 (7350), 173-178, 2011 | 109 | 2011 |
Structural basis for the regulation of insulin-like growth factors by IGF binding proteins I Siwanowicz, GM Popowicz, M Wisniewska, R Huber, KP Kuenkele, ... Structure 13 (1), 155-167, 2005 | 109 | 2005 |
The p53-MDM2/MDMX axis–A chemotype perspective K Khoury, GM Popowicz, TA Holak, A Dömling MedChemComm 2 (4), 246-260, 2011 | 86 | 2011 |
HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs M Pabis, GM Popowicz, R Stehle, D Fernández-Ramos, S Asami, ... Nucleic acids research 47 (2), 1011-1029, 2019 | 82 | 2019 |
Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites M Dawidowski, L Emmanouilidis, VC Kalel, K Tripsianes, K Schorpp, ... Science 355 (6332), 1416-1420, 2017 | 81 | 2017 |
Transient protein states in designing inhibitors of the MDM2-p53 interaction M Bista, S Wolf, K Khoury, K Kowalska, Y Huang, E Wrona, M Arciniega, ... Structure 21 (12), 2143-2151, 2013 | 81 | 2013 |
Functional and structural characterization of Spl proteases from Staphylococcus aureus GM Popowicz, G Dubin, J Stec-Niemczyk, A Czarna, A Dubin, J Potempa, ... Journal of molecular biology 358 (1), 270-279, 2006 | 80 | 2006 |