Evolution of enhanced innate immune evasion by SARS-CoV-2 LG Thorne, M Bouhaddou, AK Reuschl, L Zuliani-Alvarez, B Polacco, ... Nature 602 (7897), 487-495, 2022 | 408 | 2022 |
SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation LG Thorne, AK Reuschl, L Zuliani‐Alvarez, MVX Whelan, J Turner, ... The EMBO journal 40 (15), e107826, 2021 | 197 | 2021 |
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena, M Laporte, RL Pearl, ... Cell host & microbe 30 (3), 373-387. e7, 2022 | 163 | 2022 |
Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers L Zuliani-Alvarez, AM Marzeda, C Deligne, A Schwenzer, FE McCann, ... Nature communications 8 (1), 1595, 2017 | 98 | 2017 |
Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages AM Piccinini, L Zuliani-Alvarez, JMP Lim, KS Midwood Science signaling 9 (443), ra86-ra86, 2016 | 87 | 2016 |
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... Research square, 2021 | 75 | 2021 |
Disrupting HIV‐1 capsid formation causes cGAS sensing of viral DNA RP Sumner, L Harrison, E Touizer, TP Peacock, M Spencer, ... The EMBO journal 39 (20), e103958, 2020 | 69 | 2020 |
Fibrinogen-related proteins in tissue repair: how a unique domain with a common structure controls diverse aspects of wound healing L Zuliani-Alvarez, KS Midwood Advances in wound care 4 (5), 273-285, 2015 | 63 | 2015 |
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis T Kehrer, A Cupic, C Ye, S Yildiz, M Bouhaddou, NA Crossland, ... Cell Host & Microbe 31 (10), 1668-1684. e12, 2023 | 47 | 2023 |
HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport H Khan, RP Sumner, J Rasaiyaah, CP Tan, MT Rodriguez-Plata, ... Elife 9, e60821, 2020 | 43 | 2020 |
SARS-CoV-2 variants evolve convergent strategies to remodel the host response M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ... Cell 186 (21), 4597-4614. e26, 2023 | 42 | 2023 |
Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4 A Maqbool, EJ Spary, IW Manfield, M Ruhmann, L Zuliani-Alvarez, ... World journal of cardiology 8 (5), 340, 2016 | 38 | 2016 |
TLR4-mediated pathway triggers interferon-independent G0 arrest and antiviral SAMHD1 activity in macrophages P Mlcochova, H Winstone, L Zuliani-Alvarez, RK Gupta Cell reports 30 (12), 3972-3980. e5, 2020 | 37 | 2020 |
Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B. 1.1. 7 variant AK Reuschl, LG Thorne, L Zuliani-Alvarez, M Bouhaddou, K Obernier, ... BioRxiv, 2021 | 36 | 2021 |
Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19 JF Varona, P Landete, JA Lopez-Martin, V Estrada, R Paredes, ... Life science alliance 5 (4), 2022 | 34 | 2022 |
Evasion of cGAS and TRIM5 defines pandemic HIV L Zuliani-Alvarez, ML Govasli, J Rasaiyaah, C Monit, SO Perry, ... Nature microbiology 7 (11), 1762-1776, 2022 | 33 | 2022 |
SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena, RL Pearl, M Laporte, ... bioRxiv, 2021.08. 05.455290, 2021 | 19 | 2021 |
Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets KM Haas, MJ McGregor, M Bouhaddou, BJ Polacco, EY Kim, TT Nguyen, ... Nature communications 14 (1), 6030, 2023 | 13 | 2023 |
Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ... bioRxiv, 2022.10. 19.512927, 2022 | 13 | 2022 |
Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization JF Varona, P Landete, JA Lopez-Martin, V Estrada, R Paredes, ... MedRxiv, 2021.05. 25.21257505, 2021 | 9 | 2021 |