53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks SF Bunting, E Callén, N Wong, HT Chen, F Polato, A Gunn, A Bothmer, ... Cell 141 (2), 243-254, 2010 | 1827 | 2010 |
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair N Bennardo, A Cheng, N Huang, JM Stark PLoS genetics 4 (6), e1000110, 2008 | 995 | 2008 |
Genetic steps of mammalian homologous repair with distinct mutagenic consequences JM Stark, AJ Pierce, J Oh, A Pastink, M Jasin Molecular and cellular biology, 2004 | 607 | 2004 |
Regulation of single-strand annealing and its role in genome maintenance R Bhargava, DO Onyango, JM Stark Trends in Genetics 32 (9), 566-575, 2016 | 542 | 2016 |
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments Y Hu, S Raynard, MG Sehorn, X Lu, W Bussen, L Zheng, JM Stark, ... Genes & development 21 (23), 3073-3084, 2007 | 364 | 2007 |
I-SceI-based assays to examine distinct repair outcomes of mammalian chromosomal double strand breaks A Gunn, JM Stark DNA repair protocols, 379-391, 2012 | 360 | 2012 |
Double-strand breaks and tumorigenesis AJ Pierce, JM Stark, FD Araujo, ME Moynahan, M Berwick, M Jasin Trends in cell biology 11 (11), S52-S59, 2001 | 332 | 2001 |
Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability C Richardson, JM Stark, M Ommundsen, M Jasin Oncogene 23 (2), 546-553, 2004 | 313 | 2004 |
RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells B Budke, HL Logan, JH Kalin, AS Zelivianskaia, W Cameron McGuire, ... Nucleic acids research 40 (15), 7347-7357, 2012 | 195 | 2012 |
Heavy metal exposure influences double strand break DNA repair outcomes ME Morales, RS Derbes, CM Ade, JC Ortego, J Stark, PL Deininger, ... PloS one 11 (3), e0151367, 2016 | 178 | 2016 |
ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair JM Stark, P Hu, AJ Pierce, ME Moynahan, N Ellis, M Jasin Journal of Biological Chemistry 277 (23), 20185-20194, 2002 | 178 | 2002 |
DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining SM Howard, DA Yanez, JM Stark PLoS genetics 11 (1), e1004943, 2015 | 161 | 2015 |
Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks JM Stark, M Jasin Molecular and cellular biology, 2003 | 148 | 2003 |
Limiting the persistence of a chromosome break diminishes its mutagenic potential N Bennardo, A Gunn, A Cheng, P Hasty, JM Stark PLoS genetics 5 (10), e1000683, 2009 | 131 | 2009 |
Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription … A Gunn, N Bennardo, A Cheng, JM Stark Journal of Biological Chemistry 286 (49), 42470-42482, 2011 | 125 | 2011 |
A dual role for UVRAG in maintaining chromosomal stability independent of autophagy Z Zhao, S Oh, D Li, D Ni, SD Pirooz, JH Lee, S Yang, JY Lee, I Ghozalli, ... Developmental cell 22 (5), 1001-1016, 2012 | 123 | 2012 |
SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells Z Wang, H Yuan, M Roth, JM Stark, R Bhatia, WY Chen Oncogene 32 (5), 589-598, 2013 | 119 | 2013 |
Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks FD Araujo, AJ Pierce, JM Stark, M Jasin Oncogene 21 (26), 4176-4180, 2002 | 119 | 2002 |
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions H Saeki, N Siaud, N Christ, WW Wiegant, PPW Van Buul, M Han, ... Proceedings of the National Academy of Sciences 103 (23), 8768-8773, 2006 | 117 | 2006 |
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity S Schwendener, S Raynard, S Paliwal, A Cheng, R Kanagaraj, I Shevelev, ... Journal of Biological Chemistry 285 (21), 15739-15745, 2010 | 112 | 2010 |