The UK‐PBC risk scores: derivation and validation of a scoring system for long‐term prediction of end‐stage liver disease in primary biliary cholangitis M Carbone, SJ Sharp, S Flack, D Paximadas, K Spiess, C Adgey, ... Hepatology 63 (3), 930-950, 2016 | 381 | 2016 |
Genetic architecture of subcortical brain structures in 38,851 individuals CL Satizabal, HHH Adams, DP Hibar, CC White, MJ Knol, JL Stein, ... Nature genetics 51 (11), 1624-1636, 2019 | 260 | 2019 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 215 | 2020 |
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states L LeBon, TV Lee, D Sprinzak, H Jafar-Nejad, MB Elowitz elife 3, e02950, 2014 | 160 | 2014 |
Inactivation of effector caspases through nondegradative polyubiquitylation M Ditzel, M Broemer, T Tenev, C Bolduc, TV Lee, KTG Rigbolt, R Elliott, ... Molecular cell 32 (4), 540-553, 2008 | 150 | 2008 |
Genetic control of programmed cell death (apoptosis) in Drosophila D Xu, SE Woodfield, TV Lee, Y Fan, C Antonio, A Bergmann Fly 3 (1), 78-90, 2009 | 140 | 2009 |
Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score M Carbone, A Nardi, S Flack, G Carpino, N Varvaropoulou, C Gavrila, ... The Lancet Gastroenterology & Hepatology 3 (9), 626-634, 2018 | 132 | 2018 |
Negative regulation of notch signaling by xylose TV Lee, MK Sethi, J Leonardi, NA Rana, FFR Buettner, RS Haltiwanger, ... PLoS genetics 9 (6), e1003547, 2013 | 109 | 2013 |
A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss E Servián‐Morilla, H Takeuchi, TV Lee, J Clarimon, F Mavillard, ... EMBO molecular medicine 8 (11), 1289-1309, 2016 | 97 | 2016 |
Genetic control of programmed cell death in Drosophila melanogaster P Cashio, TV Lee, A Bergmann Seminars in cell & developmental biology 16 (2), 225-235, 2005 | 92 | 2005 |
Vaccine implications of folate binding protein, a novel cytotoxic T lymphocyte-recognized antigen system in epithelial cancers GE Peoples, BW Anderson, TV Lee, JL Murray, AP Kudelka, JT Wharton, ... Clinical cancer research 5 (12), 4214-4223, 1999 | 89 | 1999 |
Dual roles of Drosophila p53 in cell death and cell differentiation Y Fan, TV Lee, D Xu, Z Chen, AF Lamblin, H Steller, A Bergmann Cell Death & Differentiation 17 (6), 912-921, 2010 | 87 | 2010 |
The E1 ubiquitin-activating enzyme Uba1 in Drosophila controls apoptosis autonomously and tissue growth non-autonomously TV Lee, T Ding, Z Chen, V Rajendran, H Scherr, M Lackey, C Bolduc, ... Oxford University Press for The Company of Biologists Limited 135 (1), 43-52, 2008 | 70 | 2008 |
Drosophila IAP1-Mediated Ubiquitylation Controls Activation of the Initiator Caspase DRONC Independent of Protein Degradation TV Lee, Y Fan, S Wang, M Srivastava, M Broemer, P Meier, A Bergmann PLoS genetics 7 (9), e1002261, 2011 | 63 | 2011 |
Prevalence of type 2 diabetes in children in Birmingham S Ehtisham, J Kirk, A McEvilly, N Shaw, S Jones, S Rose, K Matyka, T Lee, ... BMJ 322 (7299), 1428, 2001 | 59 | 2001 |
Folate binding protein peptide 191-199 presented on dendritic cells can stimulate CTL from ovarian and breast cancer patients. DK Kim, TV Lee, A Castilleja, BW Anderson, GE Peoples, AP Kudelka, ... Anticancer research 19 (4B), 2907-2916, 1999 | 56 | 1999 |
Greater transplant-free survival in patients receiving obeticholic acid for primary biliary cholangitis in a clinical trial setting compared to real-world external controls CFM Perez, H Fisher, S Hiu, D Kareithi, F Adekunle, T Mayne, E Malecha, ... Gastroenterology 163 (6), 1630-1642. e3, 2022 | 42 | 2022 |
A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke J Szostak, ET Wong, B Titz, T Lee, SK Wong, T Low, KM Lee, J Zhang, ... American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020 | 41 | 2020 |
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version … BW Phillips, WK Schlage, B Titz, U Kogel, D Sciuscio, F Martin, P Leroy, ... Food and Chemical Toxicology 116, 388-413, 2018 | 39 | 2018 |
X chromosome contribution to the genetic architecture of primary biliary cholangitis R Asselta, EM Paraboschi, A Gerussi, HJ Cordell, GF Mells, RN Sandford, ... Gastroenterology 160 (7), 2483-2495. e26, 2021 | 38 | 2021 |