| How many human proteoforms are there? R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ... Nature chemical biology 14 (3), 206-214, 2018 | 869 | 2018 |
| Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects MM Yore, I Syed, PM Moraes-Vieira, T Zhang, MA Herman, EA Homan, ... Cell 159 (2), 318-332, 2014 | 801 | 2014 |
| Peptidomic discovery of short open reading frame–encoded peptides in human cells SA Slavoff, AJ Mitchell, AG Schwaid, MN Cabili, J Ma, JZ Levin, ... Nature chemical biology 9 (1), 59-64, 2013 | 685 | 2013 |
| Toddler: an embryonic signal that promotes cell movement via Apelin receptors A Pauli, ML Norris, E Valen, GL Chew, JA Gagnon, S Zimmerman, ... Science 343 (6172), 1248636, 2014 | 660 | 2014 |
| The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 651 | 2014 |
| Identification of protein pheromones that promote aggressive behaviour P Chamero, TF Marton, DW Logan, K Flanagan, JR Cruz, A Saghatelian, ... Nature 450 (7171), 899-902, 2007 | 613 | 2007 |
| mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide A Matsumoto, A Pasut, M Matsumoto, R Yamashita, J Fung, E Monteleone, ... Nature 541 (7636), 228-232, 2017 | 600 | 2017 |
| Activity-based probes for the proteomic profiling of metalloproteases A Saghatelian, N Jessani, A Joseph, M Humphrey, BF Cravatt Proceedings of the National Academy of Sciences 101 (27), 10000-10005, 2004 | 563 | 2004 |
| Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism A Zarrinpar, A Chaix, ZZ Xu, MW Chang, CA Marotz, A Saghatelian, ... Nature communications 9 (1), 2872, 2018 | 460 | 2018 |
| Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models RU Svensson, SJ Parker, LJ Eichner, MJ Kolar, M Wallace, SN Brun, ... Nature medicine 22 (10), 1108-1119, 2016 | 458 | 2016 |
| Inactivation of N-Acyl Phosphatidylethanolamine Phospholipase D Reveals Multiple Mechanisms for the Biosynthesis of Endocannabinoids D Leung, A Saghatelian, GM Simon, BF Cravatt Biochemistry 45 (15), 4720-4726, 2006 | 431 | 2006 |
| Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex JJ Howell, K Hellberg, M Turner, G Talbott, MJ Kolar, DS Ross, G Hoxhaj, ... Cell metabolism 25 (2), 463-471, 2017 | 382 | 2017 |
| Assignment of endogenous substrates to enzymes by global metabolite profiling A Saghatelian, SA Trauger, EJ Want, EG Hawkins, G Siuzdak, BF Cravatt Biochemistry 43 (45), 14332-14339, 2004 | 382 | 2004 |
| Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity AH Lichtman, D Leung, CC Shelton, A Saghatelian, C Hardouin, ... Journal of Pharmacology and Experimental Therapeutics 311 (2), 441-448, 2004 | 382 | 2004 |
| Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis P Chen, H Zuo, H Xiong, MJ Kolar, Q Chu, A Saghatelian, DJ Siegwart, ... Proceedings of the National Academy of Sciences 114 (3), 580-585, 2017 | 373 | 2017 |
| A chiroselective peptide replicator A Saghatelian, Y Yokobayashi, K Soltani, MR Ghadiri Nature 409 (6822), 797-801, 2001 | 358 | 2001 |
| Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence G Sulli, A Rommel, X Wang, MJ Kolar, F Puca, A Saghatelian, MV Plikus, ... Nature 553 (7688), 351-355, 2018 | 336 | 2018 |
| Defining the metabolome: size, flux, and regulation N Zamboni, A Saghatelian, GJ Patti Molecular cell 58 (4), 699-706, 2015 | 320 | 2015 |
| SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism Y Oishi, NJ Spann, VM Link, ED Muse, T Strid, C Edillor, MJ Kolar, ... Cell metabolism 25 (2), 412-427, 2017 | 311 | 2017 |
| Desorption/ionization on silicon nanowires EP Go, JV Apon, G Luo, A Saghatelian, RH Daniels, V Sahi, R Dubrow, ... Analytical chemistry 77 (6), 1641-1646, 2005 | 310 | 2005 |
