Cu (II) mediates kinetically distinct, non-amyloidogenic aggregation of amyloid-β peptides JT Pedersen, J Østergaard, N Rozlosnik, B Gammelgaard, ... Journal of Biological Chemistry 286 (30), 26952-26963, 2011 | 146 | 2011 |
Analysis of Protein Aggregation in Neurodegenerative Disease JT Pedersen, NHH Heegaard Analytical Chemistry, 2013 | 122 | 2013 |
Rapid formation of a preoligomeric peptide–metal–peptide complex following copper (II) binding to amyloid β peptides JT Pedersen, K Teilum, NHH Heegaard, J Østergaard, HW Adolph, ... Angewandte Chemie 11 (123), 2580-2583, 2011 | 85 | 2011 |
Amyloid-β and α-synuclein decrease the level of metal-catalyzed reactive oxygen species by radical scavenging and redox silencing JT Pedersen, SW Chen, CB Borg, S Ness, JM Bahl, NHH Heegaard, ... Journal of the American Chemical Society 138 (12), 3966-3969, 2016 | 82 | 2016 |
Rapid Exchange of Metal between Zn7–Metallothionein-3 and Amyloid-β Peptide Promotes Amyloid-Related Structural Changes JT Pedersen, C Hureau, L Hemmingsen, NHH Heegaard, J Østergaard, ... Biochemistry 51 (8), 1697-1706, 2012 | 74 | 2012 |
A new water-soluble Cu (II) chelator that retrieves Cu from Cu (Amyloid-β) species, stops associated ROS production and prevents Cu (II) induced Aβ aggregation S Noël, F Perez, JT Pedersen, B Alies, S Ladeira, S Sayen, E Guillon, ... Journal of Inorganic Biochemistry 117, 322-325, 2012 | 44 | 2012 |
The pKa Value and Accessibility of Cysteine Residues Are Key Determinants for Protein Substrate Discrimination by Glutaredoxin KS Jensen, JT Pedersen, JR Winther, K Teilum Biochemistry 53 (15), 2533-2540, 2014 | 42 | 2014 |
Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties. M Jensen, A Canning, S Chiha, P Bouquerel, JT Pedersen, J Østergaard, ... Chemistry (Weinheim an der Bergstrasse, Germany) 18 (16), 4836-4839, 2012 | 37 | 2012 |
Aggregation‐Prone Amyloid‐β⋅ CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions JT Pedersen, CB Borg, TCT Michaels, TPJ Knowles, P Faller, K Teilum, ... ChemBioChem 16 (9), 1293-1297, 2015 | 29 | 2015 |
Affinity capillary electrophoresis for identification and investigation of human Gc‐globulin (vitamin D‐binding protein) and its isoforms interacting with G‐actin JT Pedersen, J Østergaard, G Houen, NHH Heegaard Electrophoresis 29 (8), 1723-1733, 2008 | 26 | 2008 |
Nanosecond dynamics at protein metal sites: an application of perturbed angular correlation (PAC) of γ-rays spectroscopy S Chakraborty, S Pallada, JT Pedersen, A Jancso, JG Correia, ... Accounts of chemical research 50 (9), 2225-2232, 2017 | 9 | 2017 |
pH dependence of amyloid-beta-Cu (II) binding and oligomerization kinetics JT Pedersen, CB Borg, K Teilum, L Hemmingsen JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S755-S755, 2014 | | 2014 |
Binding of Cu2+ to the islet amyloid polypeptide (IAPP) J Andersen-Usaj, AC Bonde, J Pihl, MLF Thomsen, M Shavit, ... JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S812-S812, 2014 | | 2014 |
Islet amyloid polypeptide (IAPP)-Structural effects of Zn2+ M Shavit, AC Bonde, J Pihl, MLF Thomsen, JT Pedersen, ... JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S813-S813, 2014 | | 2014 |
Role of Cu 2+ in oligomerization and aggregation of alzheimer's amyloid-ß peptides JT Pedersen PhD thesis, University of Copenhagen, 2011 | | 2011 |